Don’t know if anyone has ever been in a similar situation cushings

[Tigercocolove718648]

My dog has cushings and is currently pretty sick. I gave her a 5mg vetoryl pill this morning. Except she did not swallow it she chewed it and the contents inside spilled everywhere! Currently very nervous for my exposure to it!

[Tigercocolove718648]

My dog is also extremely sick. She’s very shaky doesn’t want to eat. Very lethargic. Her vet wants her on vetoryl a couple of days before I bring her back in

[labblab]

Hello and welcome! You are correct that there are warnings against directly handling the capsule contents, especially for pregnant women. However, I doubt that one isolated instance of contact poses a significant risk, especially if you washed your hands thoroughly after getting any powder on them. It might be a good idea to keep some disposable medical gloves on hand, though, just in the event of a repeat. That way you can protect your hands from direct exposure during administration of the capsule or during any necessary cleanup. You can buy boxes of gloves quite inexpensively at grocery stores or pharmacies.

Can you tell us more about your girl? I’m so sorry that she’s not doing well right now. Has she been taking the Vetoryl for long? How about the symptoms that led to the Cushing’s diagnosis? Anything that you care to share about her overall health history will be a help to us, as well as the specifics associated with her Cushing’s treatment. We’re really glad you’ve found us and once we learn more about your girl, we’ll do our best to offer you our thoughts and suggestions.

Marianne

[Squirt's Mom]

As long as you are not pregnant nor trying to get pregnant you should be fine. If either of those two factors is present I would call the doc in the morning and tell them what happened. Make sure you can estimate about how much got on your hands and for how long. They will also want to know the dose she is taking. But I wouldn't panic. I think it would take a heavy exposure several times to do any real harm so try to breath for now. IF either of those two things is true for you then call in the morning but I think you will find it's nothing to worry about.

Now about your baby....when you say "pretty sick" what do you mean by that? Is she vomiting? diarrhea? coughing? Can you describe what you are seeing that makes you think she is pretty sick?

How long has she been on treatment? What dose is she taking and how much does she weigh? I am asking trying to make sure the cortisol hasn't dropped too low.

Glad you found us!
Hugs,
Leslie

[labblab]

My dog is also extremely sick. She’s very shaky doesn’t want to eat. Very lethargic. Her vet wants her on vetoryl a couple of days before I bring her back in
I think we were all three writing at the same time earlier. But based on these symptoms I’m terribly worried about your vet’s instructions to keep on giving the Vetoryl!! These can be classic symptoms of drug overdose, and if so, continuing to give the Vetoryl can cause a life-threatening situation.

How long has she been taking the Vetoryl?

[Tigercocolove718648]

Hi! Thanks for the responses! She is on 5mg! The thing is he took her off two months ago bc even though her tests came back good her BUN was through the roof, after two weeks off vetoryl all
Her levels went back to normal. Flash forward two months and she’s worst than she’s ever been, so he put her on 5mg instead of 10mg she has adrenal dependent cushings and I just feel it’s not good. My heart hurts so bad bc I feel I may lose her. I can’t even really think straight honestly! We are trying to conceive �� mostly the reason I worried.

[labblab]

How many doses has she had now that she’s started back? Regardless, I don’t think it’s safe to continue giving Vetoryl to a dog who is shaking, lethargic and won’t eat. I’m not a vet, so all I can give you is my personal opinion. But in terms of triggering an acute crisis, I think it’s more dangerous for a dog’s cortisol level to drop too low than it is for it to run higher. And especially if your dog developed kidney issues while taking the Vetoryl before, I don’t think it’s safe to continue to give it to her when she’s acting so ill again.

I’m so sorry that she’s doing so poorly!! I totally understand your worry and confusion about all this. But if she was my dog, I’d tell the vet that you don’t feel safe giving her any more Vetoryl and you want her to be re-examined *now.*

If she does have an adrenal tumor, it’s sadly possible that it could be growing and/or cancerous, and that could account for her turn for the worse. An abdominal ultrasound could let you know more about the status of the tumor, or issues with other organs such as her kidneys. Or if she’s not had bloodwork done recently, that would be important to repeat now, too. So I’d want the vet to actually see her before giving any more Vetoryl at all.

As far as your exposure to the powder, you can always call your doctor to put your mind at ease. Or you could try contacting Dechra, the maker of Vetoryl. The link below gives you contact info for their U.S. office. But I doubt that a single instance like this should be too worrisome.

https://www.dechra-us.com/contact/technical-support

Please do keep us updated, OK?
Marianne

[Tigercocolove718648]

Also, I don’t know if I actually touched any but I don’t know! I cleaned it with a wipe anywhere I saw it and threw it away immediately and washed my hands, I also gave my dog a bath after and in the bath the other half of the pill came out of her mouth! :eek: and I grabbed it with tissue and flushed it down the toilet. My poor coco
Has been through so much. I did wash my hands And took of my clothes and I thought I saw specs of the medicine on my clothes I just don’t know. I also have a little baby and I’m worried some got on her. I know I may be overthinking. Bc if overthinking was a sport I’d win gold medals. But also I’m just nervous for my exposure and then I’m also so nervous about cocos health bc she really doesn’t look good at all.

[Tigercocolove718648]

It is adrenal dependent. It was confirmed on an ultrasound. She had bloodwork
On Monday and I think everythjng was fine except her liver enzymes were very very high. I’m thinking the worse. I just emailed her vet bc I’m afraid she’s going to die.

[labblab]

I totally understand!! I’m the queen of worrying!! But it sounds to me as though you took good care of cleaning everything and the tiny bit of powder that might still have been clinging anywhere wouldn’t be enough to be harmful.

I’m just so sorry about little Coco not doing well, though. I know she’s your canine baby, and all this has got to be so upsetting :-(((((. We’ll stick right here by your side, truly, so just keep writing any time you want, OK?

[Tigercocolove718648]

Thank you. Her vet told me to bring her in first thing in the morning. All she has done all day is sleep. She woke up one time only to drink water. She’s very weak. And I’ve her for 12 years and I love her so much

[labblab]

I wish I could give you a giant hug in person, but I’m sending one flying to you across the miles! There’s nothing worse than feeling helpless when a soul you love so dearly is struggling. It just rips your heart wide open! But you’re doing the very best thing for Coco, and above all, you’re loving her. That’s the greatest gift you can possibly give her. Fingers crossed for you both tomorrow. And no matter what, we’ll be here for you.

[Tigercocolove718648]

Thank you <3

[labblab]

Surely hoping for some better news about sweet Coco today. Whenever you’re ready to give an update, we’ll be so anxious to hear.

Marianne

[Tigercocolove718648]

Hi!! So she’s doing better they gave her iv fluids and she’s finally eating today. Still really slow. And shaking a lot. Her vet really thinks she should continue on the 5mg. I just am nervous! Her liver enzymes are very very high ( don’t know the number but it was very high)she’s still very slow. He suggested another ultrasound since her last one was 4 months ago.

[Tigercocolove718648]

Coco is not doing well it’s midnight and she can’t walk at all. She breathing very weird.

[Tigercocolove718648]

She’s sleeping now. Taking her at 7am to the vet.

[Joan2517]

Don't even try to give her the Vetoryl, no matter what the vet says. We refrain from giving it when they are not well and especially not eating. I hope the vet visit this morning brings some relief to both of you.

[labblab]

Oh, I’m hoping so, too! Sending more healing thoughts to little Coco as we await news this morning.

[Squirt's Mom]

Please let us know what you learn!
Hugs
Leslie

[Tigercocolove718648]

Hi guys! So coco is doing much better! She started the vetoryl 5mg except it makes her kidneys go crazy. So now she has to to stop. And idk �� I also don’t know if this is a good Place to ask, but we have a brand new bottle of liquid 5mg vetoryl, literally never been used. Do you think the vet can take it back? Since it’s compounded to liquid it’s way more expensive than the pill ($156.17)

[Squirt's Mom]

I would certainly ask the vet if they could pass it on to an elderly patient and if that's not an option for them, check with your local Humane Society or local rescues to see if they can use it.

When you say it made her kidneys "go crazy" can you tell us what that means? What happened with the kidneys on this medicine?