Suki - New diagnosis

[Shiloh25]

Hello. I have a scheduled LDDS test on Saturday for my 6.5 year old French Bulldog Suki. Vet is 99% sure it's cushings. She has the common signs of increased water intake/increased peeing and accidents in the house, loss of hair on top of her head, behind, back legs and tummy. She had a UTI in Nov of 2016 and was fine until this past Dec. Had another one (always had a bit of hair loss on top o her head and always thougt that was just her) and 4 weeks ago the increased water intake and peeing problems got worse and I noticed the more hair loss above.

Here results from blood work and urine test from two weeks ago are as follows: Her Thyroid test came back normal accept a 2+ Result on her Hemolysis everything else in in range

CTHY1 - CANINE COMPREHENSIVE SENIOR WELLNESS
Biochemistry
NAME RESULT RANGE UNITS
A/G RATIO 1.31 0.60-1.90
ALBUMIN 38.0 26.0-44.0 g/L
GIOBULIN 29.0 18.0-38.0 g/L
PROTEIN(T) 67 51-74 g/L
BILLRUBIN(T) 3.1 0.0-4.5 UMOL/L
BILLRUBIN(C) 0.0 0.0-2.0 UMOL/L
ALP 77 5-141 U/L
ALT 142 6-118 U/L FLAGGED AS HIGH
AST 45 5-71 U/L
CREATINE KINASE(CK) 201 35-528 U/L
Amylase 97 280-1400 U/L
LIPASE 487 20-560 UMOL/L
CHOLESTORAL 7.00 2.50-9.90 MMOL/L
GLUCOSE 3.8 3.0-7.0 MMOL.L
UREA 5.2 3.0-11.5 MMOL/L
CREATINE 47 24-140 UMOL/L
NA/K RATIO 32 24-45
POTASSIUM 4.7 3.6-6.0 MMOL/L
SODIUM 151 144-162 MMOL/L
CHLORIDE 114 106-126 MMOL/L
CALCIUM 1.80 2.04-3.04 MMO;/L FLAGGED AS LOW
PHOSPHORUS 1.76 0.70-2.50 MMOL/L
HEMOLYSIS 2+ BOLDED ON REPORT
LIPEMIA NORMAL
ICTERUS NORMAL

ENDOCRINOLOGY
FREE T4 15.3 10.0-45.0 PMOL/L

HEMOTOLOGY
RBC 7.4 5.4-9.0 10^12/L
HGB 186 127-203 G/L
HCT 0.51 0.35-0.60 L/L
MCV 68.5 56-0.77-10 FL
MCH 25.1 19.5-28.0 PG
MCHC 366 300-405 G/L
PLATELETS 323 143-550 10^9/L
WBC 8.00 5.20-17.10 10^9/L
BAND NEUTRO. 0.00 0.00-0.90 10^9/L
SEG. NEUTRO 6.80 3.00-11.50 10^9/L
LYMPHOCYTES 0.72 0.90-4.66 10^9/L FLAGGED AS LOW
MONOCYTES 0.57 0.10-204 10^9/L
EOSINOPHILS 0.08 0.00-1.95 10^9/L
BASOPILS 0.05 0.00-0.25 10^9/L
RBC MORPHOLOGY NORMAL
PIT'S MORPHOLOGY NORMAL
WBC MORPHOLOGY NORMAL

URINE URCC CORTISOL/CREATINE RATIO 79.18X 10^(-6) COMMENT SAID 1
RESULT INTERPRETATIONS OF 1 =
URINARY CORTISOL/CREATINE RATION
NORMAL DOGS : CORTISOL/CREATINE RATIO <10 X 10^(-6)
ADRENOCORTICAL HYPERFUNCTION: CORTISOL/CREATINE RATIO >10 X 10^(-6)

THE REST OF THE URINE TEST
APPEARENCE CLEAR
COLOR PALE YELLOW
PH 8.0
SPECIFIC GRAVITY 1.005 THIS IS BOLDED
GLUCOSE NEGATIVE
NITRITE NEGATIVE
BLOOD NEGATIVE
BILIRUBIN NEGATIVE
UROBILINOGEN NEGATIVE
KETONES NEGATIVE
PROTEIN NEGATIVE
LEUKOCYTES NEGATIVE

URINALYSIS- MICROSCOPY
CASTS NONE SEEN
EPHITHELIAL CELLS NONE SEEN
FAT DROPLETS NONE SEEN
RBC NONE SEEN
WBC NONE SEEN
BACTERIA NONE SEEN
YEAST NONE SEEN

Is it easy to tell if this is the beginning stages and I've caught it early enough as her blood work from Nov 2016 don't show the same results. I'm hoping we can manage this and she can still have a long life ahead

TIA Tina

[Squirt's Mom]

Hi Tina and welcome to you and Suki! :)

I've approved your post so members can see it and start replying when they can. You might want to check your spam or junk folder for a message from K9Cushings that you can reply to that will set up your post to go right thru from now on. ;)

Why does your vet think she has Cushing's? From the lab work so far I don't really see anything that indicates Cushing's. We typically see VERY high values for ALP and hers are normal as are the CHOL and TRIG as well as the T4. What is a bit concerning are the low lymphocytes as this can be an indication of Lymphoma and Bulldogs are among the breeds prone to this disease. The signs you mention are in keeping with Cushing's tho in spite of the lab work. I would want to ask the vet about the possibility of Lymphoma when you see her Sat just to ease your mind (and mine! :D I'm a big ole worry wort!)

I'm glad you found us and look forward to learning more about your sweet girl! You need to know that you and Suki now belong to our little family here and we will be with you every step of the way - no matter what.

Hugs,
Leslie

PS I took the liberty of adding Suki's name to the title so you can find her thread more easily. We like to keep all posts about each pup in one thread. It's easier to keep up with the history that way.

[Harley PoMMom]

Hi and welcome from me as well!

I have only a moment to post but I wanted to let you know that I went ahead and manually approved your membership so please just disregard the validation email that was sent to you from k9cushings. :)

Lori

[molly muffin]

Hello and welcome from me too. Do let us know what the LDDS test results are. (there will be 3 values, a pre, 4 hour and 8 hour result)

It is possible that it is cushings and the LDDS should tell us more. Have you discussed possible treatment options with the vet if the results are positive?