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Kota&HursMom
12-31-2016, 08:54 PM
Hello all!

I found your forum about two months ago, before my dog's diagnosis (but my intuition believed she had Cushings), but waited to join until it was a definite diagnosis. Dakota was diagnosed in December. She just turned 8 on Nov. 11th.

A bit of a back story...

In August I moved back to California from Omaha for a teaching position. Unfortunately the moved happened at an inconvenient time, husband had just moved back to California and we were depleted, so I moved into a RV until I could find a better living situation.

In September, I noticed that she was peeing inside the RV during the day. She had never done this and I was alarmed. At first I chalked it up to the fact that she was living in a new area in a small living situation. Unfortunately she continued so about two weeks later we took her to the vet. The vet was at a loss, because at this point the only symptom was the excessive water intake and urination. I thought it might be a urinary tract infection, so I requested pills.

The vet suggested that we get an ultrasound done to see if it was a a kidney infection or worse. Because I just started my new job, we waited until October to have the ultrasound done. The ultrasound showed nothing. The vet then believed it could be leptospirosis or diabetes, even saying there was a very small chance that it was Cushings because nothing was found on the adrenal glands (course, now I know most Cushings is by a tumor in the pituitary gland). By this time, she was in a crate during the day getting bathed daily because she continued to pee during the day. I started waking up two times a night to let her out. I started doing my own research and really had decided that she might have Cushings. Only having my gut and her excessive urination to go on, I didn't fully trust myself (as a vet should know better).

The vet took her blood shortly after ultrasound, in November sometime, and concluded that she had leptospirosis. We put her on the medication for it. After we started the medication the vet wanted to do another blood test, to see what they leptospirosis was doing. That blood test showed that her liver levels were high and then the vet asked for a urine test, thinking it was diabetes. Then she noticed in that test, a count was high, so the vet suggested a cortisol test. By this time, my mother in law passed from stage four liver cancer and Dakota's vet visits were paused until beginning of December.

We took her in December for the cortisol test and on December 13, we received a phone call that she did in fact have Cushings. Because of the high chance of overdose, I started her on the meds - Vetoryl 60mg - on Saturday when I was home for winter break.

She has had a complete turnaround with water intake and urination. However two days ago I noticed that she was extremely wobbly and her equilibrium seemed off. Took her to the vet today and found out she has an ear infection for probably a while as Cushings dropped her immune system. So now we're combating Cushings and her ear infection.

I have done as much research as I could trying to make sure I know all the possible side effects of Vetoryl and make sure I am advocating as best as I can for Cushings in Dakota.

I'm hoping that I caught it early enough that she still has quite a life to live. My husband and I will be switching vets within the year (as we're moving to a more affordable location and not happy with the one we have) so hoping that she continues to improve and her tests results are easily transferred.

I'm hoping that joining this forum will make me a better advocate for her condition and make me more aware of the disease. I've scared myself with research but I want to be prepared for worst case and live with best case.

labblab
12-31-2016, 09:11 PM
Hello and welcome to you and sweet Dakota! We are so glad you've joined our family, and kudos to you for working so hard to advocate for your girl under some very trying circumstances.

There will be much for us to talk over in the days to come, but whenever folks tell us that their dogs are acting weak or wobbly after starting Vetoryl treatment, I always worry about overdose. It may certainly be the case that an ear infection could account for problems with equilibrium. But it is also possible that Dakota's cortisol level may have dropped abruptly enough to be causing her some problems. After two weeks of Vetoryl treatment and the presence of these issues, it would be desirable to have her adrenal response to the medication evaluated with an ACTH blood test. Has your vet talked with you about testing her cortisol level? It is really important to do so, especially when a dog is acting unwell. Unfortunately, an ACTH test is fairly expensive, but even a basic resting cortisol level could give you an idea as to whether or not Dakota's cortisol has dropped too low.

How much does Dakota weigh? I ask because current recommendations are to begin dosing at no more than 1 mg. per pound as a daily total. So if Dakota's starting dose exceeds that ratio, that would give even more reason for concern about a possible overdose.

Thanks in advance for any additional info, and once again, welcome!

Marianne

Kota&HursMom
01-01-2017, 12:24 PM
She was scheduled for an ACTH blood test yesterday but I was nervous about an overdose so I gave her prednisone on Friday night and did not give her Vetroyl yesterday morning. Because she didn't have it in her system, we couldn't do the test. Prednisone did nothing to help her wobbliness unfortunately - that's why I did not believe it was the Vetroyl.

She goes back on Friday for the ACTH test. We got her insurance before all of this happened so as of right now, everything is covered with only a slight hiccup.

Yesterday when she went to the vet, she was at 59.6.

molly muffin
01-09-2017, 11:48 PM
Hello and welcome from me too.

Did you have the ACTH on Friday? do you have the results yet? Should be a pre and a post result.

Was she on vetroyl when having the ACTH if she had it?

Is the ear infection cleared up?
How is she doing with the peeing/drinking?

Oh my you have had a rough go of it lately. I am sorry. When it rains it pours it seems like. :(

Let us know how things are going with you and Dakota.