Cushing's, PTE, vetoryl and apoquel

[T4nia]

Hi everyone,

Hope you have been having a nice week.

My 10-year-old, 7.2-kg (15.9-lb) lhasa apso named Mika was diagnosed with Cushing's and has been taking vetoryl (trilostane) for a year and half now (19mg/day). Mika also suffers from atopic dermatitis and has been taking cyclosporine (50mg/day). Mika has been having more skin lesions lately. She constantly scratches and licks them.

A vet suspects that cyclosporine might have ceased to be effective and recommended switching to Apoquel (oclacitinib maleate). Mika takes a lot of medications everyday (she has had a PTE, pulmonary thromboembolism. I can provide the full list of medications) and I am not sure whether Vetoryl and Apoquel can be administered together. The vet said that no research has been done on the interaction of Vetoryl and Apoquel and, therefore, I should decide what to do...

I really do not know how to proceed and would appreciate any advice on the matter. Please help me help Mika. :confused:

Thank you,

Tania
Brazil

[Squirt's Mom]

Hi and welcome to you and Mika!

The first thing I would do is see a dermatologist if you haven't already to make absolutely sure this is not CC - Calcinosis cutis - instead of atopic dermatitis. CC is an uncommon complication with Cushing's and a derm vet can tell you pretty quickly if your baby has this or not. If it truly is atopic dermatitis, as far as I know there is no problem using Apoquel along with Vetoryl (Trilostane). Some of the others may have more info on that that I and I am sure they will be along soon to talk with you.

Hugs,
Leslie and the gang

PS. Here is a link with some pics of CC (they are pretty graphic so fair warning)
https://www.google.com/search?q=calcinosis+cutis+dog&client=ubuntu&hs=dVg&sa=X&channel=fs&biw=1264&bih=556&tbm=isch&tbo=u&source=univ&ved=0ahUKEwjMxe-C7OvNAhVX7WMKHWSzARIQsAQIMQ