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Masonsjourney9915
04-19-2016, 09:38 AM
Good Morning All. I can't believe that I am here and I apologize for my ignorance as we were just told our puppy has a confirmed diagnosis of Atypical Cushing's disease and I have little to no knowledge about this disease.

Some background on our little man Mason -- he is 7.5 MONTHS old and has been struggling with health issues almost the entire time we have had him. He is a lab/beagle/?? mix and was 9 weeks old when we adopted him. He was the best puppy when we brought him home. Always slept through the night in his crate and never complained about going in, was easily house broken and training has been going well. When he was about 4.5 months old he refused to go into his crate, stopped sleeping through the night and was coughing/sneezing regularly. We brought him to the vet and he was diagnosed with bronchitis. This was beyond upsetting to us since he was given all of his vaccinations in a timely manner. Luck of the draw I guess! He was prescribed antibiotics and I could tell he was feeling better as he was going back in his crate happily, playing and overall just acting like a puppy. He was also given drops for a yeast infection in both of his ears.

When he turned 6 months he was neutered and that was a longggg 10 days in a cone with a wild puppy! But during this time his appetite diminished but we chalked it up to the surgery and everything. His stitches were removed on a Monday and by Thursday we were back at the vet. Mason was refusing to eat but drinking a significant amount of water and peeing all the time. He was not sleeping through the night and was just overall not himself. Our vet did some blood work and noticed that Mason's Cortisol levels were extremely low. With that being said he decided he wanted to test him for Addison's. We dropped him off on a Saturday for the test and when the results came back we had no answer as he did not test positive for Addison's.

At this point Mason still hadn't eaten a full days worth of meals for almost 3 weeks. He was acting 'cranky' drinking a lot of water still, acting extremely restless and showing signs of distress (excessive panting, whining, etc) Our vet was determined to figure out what was wrong with him. He had an ultrasound done on his abdomen and told us that although extremely rare in such a young dog, he wanted to test for Cushing's.

Low and behold, yesterday we got the phone call that Mason has Atypical Cushings. We are going to sit down with the vet either this afternoon or tomorrow to go over the disease itself as I would really like to understand it more with numbers and see his actual results.

I guess the whole point of my post right now isn't really to ask any questions but more or less just type out my story and get it out there and try to make sense of the fact that our little 7.5 MONTH old puppy was just diagnosed with something he will have to deal with for the rest of his life. Heartbreaking. I don't even know what the prognosis for a dog his age is. Everything I've read has dogs being diagnosed much much much later in life.

Has anyone here heard of a puppy having Atypical Cushings?

Thanks for listening all!

Harley PoMMom
04-19-2016, 04:27 PM
Hi and welcome to you and Mason!

I am so sorry to hear that your poor sweet Mason is having such a tough time, and he is a very lucky boy to have you as his pet parents.

I've been on this forum for 7 years now and have never seen a dog of Mason's age being diagnosed with Atypical Cushing's. Atypical Cushing's is when the cortisol is normal but one or more of the adrenal sex hormones are elevated, and to me, since Mason is so so young I believe he would have an abnormal level of these sex hormones, was this diagnosis made from the adrenal panel that was sent to the University of Tennessee lab?

Dog's with Atypical Cushing's generally have the same symptoms of a dog with conventional Cushing's, and a lack of appetite is not normally seen. Was a chemistry and CBC blood panel done and if so could you post anything there that is marked abnormal and please include the normal reference ranges...thanks! Could you tell us what test the vet performed that showed Mason's cortisol was low, and could you post those results?

We have a ton of information regarding Atypical Cushing's in our Helpful Resource Forum and I'm including a link that will take you there: http://www.k9cushings.com/forum/showthread.php?t=198

If you have any questions please do not hesitate to ask them and know we are here to help in any way we can.

Hugs, Lori

labblab
04-19-2016, 05:42 PM
Hello, and welcome from me, too! Lori has given you a great introduction, and I agree 100% with the things she has written. Personally, instead of Cushing's, I would be far more suspicious that something went awry in conjunction with the neutering surgery. It just seems like too big a coincidence that the problems all arose at that time.


When he turned 6 months he was neutered and that was a longggg 10 days in a cone with a wild puppy! But during this time his appetite diminished but we chalked it up to the surgery and everything. His stitches were removed on a Monday and by Thursday we were back at the vet. Mason was refusing to eat but drinking a significant amount of water and peeing all the time. He was not sleeping through the night and was just overall not himself.
We'll look forward to getting additional info about the Atypical Diagnosis. But I believe I'd welcome a second opinion from another vet as to whether or not the surgery could have affected Mason's hormone profile, general physiology, or behavior in an unexpected way...

Marianne

molly muffin
04-19-2016, 09:55 PM
Hello and welcome from me too.

First off lets talk about what atypical cushings actually is. It's when at least 2 of the sex hormones are elevated but not the cortisol. The only place that does this diagnostic test is the university of tenn. You should have results from them if that test was done. Atypical causes some of the same symptoms as cushings, such as hair loss, thinning skin, drinking, etc.

The treatment for it is rather benign, in that it is melatonin and lignans. However, moving on from that, he just underwent neutering so those hormones might be off at the moment, but it seems likely that something involved with that surgery could have caused some of the problems and if it were me I would see an Internal Medicine Specialist to get that sorted out for sure. I have never heard of a puppy that young having any type of cushings, be it regular or atypical.

Next thought is allergies. It is not uncommon to bring home a puppy that has a bunch of allergies that show up in things like ear infections, scratching, infections, etc. and could also account for the bronchitis in one so young.
Same thing, see a doggie dermatologist and get thorough allergy testing. This might prevent a host of problems going forward and you can work around a possible food allergy, which I suspect he might have.

Those are my initial thoughts based on what you have told us so far and just what I wanted to add to Lori and Mariannes thoughts.

Welcome to the forum