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View Full Version : 8 year old pit waiting on confirmation of Cushings. What's cushings, what isn't?



LaurenKimberly
03-06-2015, 01:23 AM
Our 8 year year old blue pit, Smokey, is showing symptoms of Cushings. His bloodwork will be back Saturday AM. I'm reading online about typical Cushings symptoms, but wondering if some of his other issues are stemming from the disease. Here's a list of what we are trying to address.

Skin/coat:
We previously were, and still are, treating him for allergies. Food and environmental. He has a terrible odor, crusts on the edges of his ears, bumps and lesions on his skin, black heads (calcinosis cutis?) on his belly and privates, hard lumps and sparse hair on his tail, discolored/dark nails, and black spots on his coat. And did I mention odor?!?! Despite frequent baths with medicated shampoo, benedryl, omega 369, and limited ingredient dog food.

Body/muscular:
He has a pot bellied appearance, face seems droopy (like his skull is bony and his skin sags, and stiff hips (what we were thinking was arthritis). Despite daily walks, which we have decreased since his hips bother him more, he has little energy. He is what some would term a "Velcro dog"... Following us from room to room. But other than that, he has zero energy and not much personality. And recently (what led to a prompt vet visit) he has started bobbing his head. Not so much like a seizure, but more like you would see in someone falling asleep sitting up. Only its often and seems unrelated to his sleep patterns. I also noticed an irregular breathing pattern.

Lastly, he drinks a ton of water. He will sit by his water bowl and whine the moment it's empty. However, he is still on his bathroom schedule of morning, afternoon, evening.

Please note that this is my boyfriends dog and I've only been around the dog 1 1/2 ish years. Prior to me addressing his skin and health issues, my boyfriend seems to have chalked his appearance, odor, hips, and malaise to old age. So I can't give a detailed history prior to that. Only rough guess responses to "how long has this been going on" and "when did he start this" questions.

Between Smokeys obvious discomfort, and the fact that we are expecting a baby this fall and moving into a new home, I personally and sympathetically want to improve his health, as much as possible.

So my question is this...
How many of these issues could be symptoms of Cushings? And if they are secondary to the disease, what have others had luck with? I'm open to both medication and homeopathic treatment options. If pictures help, I'm happy to post some of those, as well.

Thanks!

Harley PoMMom
03-06-2015, 04:23 AM
Hi and welcome to you and Smokey!

First, congratulations on the new home and the baby! I bet you are so excited!!

Now, let me see if I can explain what Cushing's is and not confuse you more. :eek: When a dog has Cushing's their body is producing excessive amounts of cortisol. There are two forms of spontaneous Cushing’s, pituitary dependent hyperadrenocorticism (PDH) and adrenal-dependent hyperadrenocorticism (ADH).

The Cushing's is caused by a tumor that is located on the pituitary or the adrenal gland. Most dogs, 85% of them, have the pituitary type (PDH) while 15% have the adrenal form (ADH), and rarely some dogs do have both.

Now, Cushing's can also be caused by a overuse of a steroid, such as prednsione which is known as Iatrogenic Cushing's. With this type of Cushing's a dog can display the same symptoms as the naturally-occurring Cushing's while the only treatment for Iatrogenic that is needed is to slowly taper the steroid use.

The head bobbing sounds more like a neurological issue and generally is not attributed to Cushing's. Symptoms usually seen in dogs with Cushing's are: increased drinking/urinating, ravenous appetite, skin/hair issues, pot-bellied appearance, panting, and muscle wasting. Cortisol is the body's natural anti-inflammatory so this plethora amount of cortisol can mask the pain from arthritis.

Regarding Smokey's skin issues has the vet mentioned performing a scraping or biopsy to determine what is causing those problems?

Cushing's is one the most difficult diseases to get a confirmed diagnosis for, and unfortunately it is often misdiagnosed. Other non-adrenal illnesses, such as diabetes and thyroid problems, do share some of the same symptoms as Cushing's and should be ruled out.

Another challenging aspect of Cushing's is that there is no test that is 100% accurate in identifying the disease, and that is why symptoms are a huge part of a diagnosis for Cushing's, and perhaps even more important than a blood test when making a Cushing's diagnosis.

It would help a lot if you could get copies of the tests that were done on Smokey and post all abnormal values here along with the reference ranges and units of measurement...e.g..ALT 150 U/L (5-50)...Thanks! If any diagnostic tests for Cushing's were performed we are especially interested in the results from those tests.

The two medications generally prescribed for canine Cushing's are Lysodren/Mitotane and Vetoryl/Trilostane. They are strong drugs and one drug is no safer than the other, adverse effects are usually not seen unless the proper treatment protocols are not followed. Also, the goal of treatment is to help abate the symptoms from Cushing's and to lower that elevated cortisol to within the therapeutic ranges. The medications do not cure Cushing's, however, if an adrenal tumor is the cause for the Cushing's than surgery is a cure. Either drug can be used to treat the pituitary or adrenal type of Cushing's.

I am providing some links from our Resource Forum where we have a wealth of information regarding Cushing's. If you have any questions please do not hesitate to ask them, ok? ;)

Trilostane/Vetoryl Information and Resources (http://www.k9cushings.com/forum/showthread.php?t=185)

Lysodren loading Instructions and related tips (http://www.k9cushings.com/forum/showthread.php?t=181)

Links to Cushings Websites (especially helpful for new members!) (http://www.k9cushings.com/forum/showthread.php?t=180)

Helpful Resources for Owners of Cushing's Dogs (http://www.k9cushings.com/forum/forumdisplay.php?f=10)

Hugs, Lori

LaurenKimberly
03-07-2015, 07:40 PM
Thank you so much for the warm welcome, overview, and links. I wish I had posted here prior to hours of researching on google. You broke down in a few paragraphs what took me days to gather from various sites.

As for test results, we are still on the edge of our seats. We have to wait until Monday for the test results. In the meantime, here's a little info.

Smokey has NOT had a skin scraping or biopsy. Previous vet visits (prior to my concerns about Cushing's), my vet diagnoses him with "skin disease" and recommended a high quality and limited ingredient dog food, benedryl, omega 369 for skin AND hips, and regular baths with a medicated shampoo (for bacterial, fungal, and yeast infections of the skin). If that combination didn't show improvement, we would need to have an allergy test done. And at our last vet when he collected blood samples, he added that he isn't going to recommend anything further until he reviews the results. His skin and coat have improved slightly in the past month or two.

As for bloodwork, he did say that in additional to a regular panel, he is looking to rule out diabetes, thyroid, liver, kidney, and a few other medical conditions that can mimic Cushing's. That in the event his blood work suggests Cushing's, there is specific tests that are needed to give a conclusive diagnosis and he will then have to refer us to a specialist.

I will post his results as soon as they come in.

Blues people
03-07-2015, 11:41 PM
Hi,
Welcome and thank you for taking up the health issues of Smokey. I see so many bully breeds going through all these symptoms, including my own. We tested for thyroid first and then cushings, but my vet started Blue on homeopathic even before results were in. It took a long 12 days because of holidays , but I firmly believe the melatonin and lignans and vitamins were a huge help within 48 hrs. And so when we did start the heavy drugs, he had a good boost and he really has done well. We worried he might have side effects.
We also have small children with us daily, and his mild aggression has subsided and he is back to his sweet, passive, self. The CC. And smell is also our concern now. So I am hoping for more input for you and myself from more experienced people. I don't post often, but I do read daily, everyone is so wonderful. I think you will feel the same . Welcome from Joan . Our Blue is an 7 yr old AB. (Not old) !