PDA

View Full Version : Adrenalectomy for 11.5 year old chihuahua mix?



djndobby
01-13-2015, 11:19 PM
Hi Everyone,
Like many of you, I found this forum after doing numerous hours of research online desperately looking for information about an adrenal gland mass found on the right side of my 11.5 year old chihuahua mix, Dobby. Dobby was diagnosed with congestive heart failure based on detection of a mild to moderate heart murmur in July of 2013. Despite the CHF, his blood works showed that everything else was normal and we decided not to do any further testing/screenings until other symptoms came up. Since then he has been on 12.5 mg of Salix once a day, 1.75 mg of Enalapril once a day, fish oil and glucosamine. We also started him on a low sodium diet consisting of Primal raw food mixed with steam chicken and rice. We have been advised by the vet that his water intake and urination will increase. Since then, we have been experiencing accidental leaks here and there. Over the last year, we’ve noticed that his energy level have decreased and thought it was due to him getting older. I’ve also decreased the amount of food in hopes of controlling his weight. He was at 12lbs the same time last year! Then during mid November 2014, he was being super picky about his food and therefore not taking his meds. He appeared to be lethargic, loss of appetite, depressed and had an episode of shivering after a shower. Took him in on 11/21/14 to do blood works and x-rays. Results from the blood works indicated that his kidneys were failing.
RBC 3.98 M/µL LOW
HCT 28.9% LOW
HGB 10.3 g/dL LOW
PLT 616 K/µL HIGH
BUN 124 mg/dL HIGH
CREA 3.4 mg/dL HIGH
PHOS 6.8 mg/dL HIGH
GGT 7 U/L HIGH
AMYL 1887 U/L HIGH
LIPA 5477 U/L HIGH
X-rays results of the thorax and abdomen revealed
1. Mild diffused bronchial lung pattern
2. Narrowed thoracolumbar intervertebral disk spaces
The vet recommended an ultrasound for 11/24/14. The ultrasound indicated that the kidneys were normal and the summary:
1. Small right adrenal mass (1.3 cm thick, 1.8 cm length)
2. Mild to moderate degenerative mitral valve disease with moderate mitral regurgitation and no left atrial enlargement
3. Incidental mild gallbladder debris

Conclusion:
No cause for recent gastrointestinal signs is determined. The differential diagnosis for the small right adrenal mass includes benign and malignant neoplasia and the mass could be functional or non-functional. The mild to moderate mitral valve disease and moderate mitral regurgitation is not clinically significant since no left atrial enlargement is present at this time.

***Full report is also included in pdf

From here, we went to another vet that was able to perform the low dex test, urine analysis and more comprehensive blood works. ***The full report is included in the pdf but according to the vet, Dobby is having early stages of kidney disease and was put on a supplement called Azodyl. The low dex test shows that he is right on the border at 1.4 but because he doesn’t have any other signs such as pot belly or hair loss, it is hard to diagnose him with Cushings. They concluded that the LDDS reveals no evidence of a functional adrenal mass.
We were then referred over to 1 of the 2 board certified surgeon in the state for a consult on 12/17/14. First impression of Dr Courtney Watkins was great! She was patient and explained as much as she could in terms that I could understand. They did a blood pressure test and it was normal. They were also able to do a quick recheck of the mass that now grew to 1.5 cm thick and 1.8 cm length. She explained that the mass appeared to be hetergenous and mottled textured which they were concerned to be a more aggressive mass. Her recommendation is adrenalectomy. I expressed my concerns about his age, CHF, and kidney disease. She assured me that the findings on the ultrasound for his heart and kidney are stable enough where they are not too concerned. They are more concerned that the mass is malignant and may start to invade the vascular area or other organs in the future and removing it before it grows bigger is optimal. ***Her full report is attached that includes what we discussed in detail.
We made the decision to have the mass rechecked tomorrow and try to come up with a decision from there. At this point no medication is needed prior to surgery based on previous lab works and a CT scan will only be recommended if they find vascular invasion on the ultrasound. My concern is the high risk of this surgery. I lost my first fur baby in May 2013 and was devastated! I’m deathly afraid of losing Dobby but I know that I would really regret it if I don’t do anything now while I have the chance. Dr Watkins seems very knowledgeable and confident but I also noticed that she only got her board certification in 2012. She also mentioned that prognosis for this surgery in her experience is pretty good. Being in Hawaii, I don’t have any well-known animal hospitals that I can go to… I was hoping that you folks could take a look at the records and see if you can spot anything or give me any advice.

Thank you for reading this lengthy thread.
dj
https://docs.google.com/file/d/0B57mNZQKrU_mbFZKekpxRFV3dzA/edit?pli=1

LauraA
01-13-2015, 11:32 PM
Sorry to read about poor Dobby. Can't help you much with the Adrenal tumor I am afraid but then are a few people on this forum that have successfully had the surgery and I am sure they will give you some sound advice as soon as they can.

Harley PoMMom
01-14-2015, 10:16 PM
Hi and welcome to you and Dobby,

I have no experience with adrenal tumors either but we do have members with dogs that have had successful adrenalectomies. Trish is one of our members, whose dog, Flynn, has gone through an adrenalectomy and she made a list of questions for people who are contemplating this type of surgery for their dog, here's that list:
Part I - Questions to ask when considering if surgery is an option for your dog’s adrenal tumour:
1. What type of tumour do you suspect, ?functional, ?non-functional, pheochromocytoma, benign, metastatic
2. Expected life span for my dog in a normal situation. If your dog is close to, at or past his expected lifespan for his breed is surgery going to be of any benefit?
3. Prognosis for my dog if we treated medically i.e. with Cushings medications. AND if we do not proceed with surgery how long do you think it would be before the tumour started adversely affecting his quality of life?
4. If he is miserable now, does the benefit of potentially risky surgery outweigh his current quality of life?
5. Are there any other health problems that could impact on a positive surgical outcome, for example: if your dog is overweight or has heart, BP, liver, kidney or lung conditions
6. Is there any sign of tumour spread – imaging should be done, including ultrasound and on advice of specialists either CT or MRI to check whether there is local invasion around the tumour, into blood vessels including vena cava or spread further away in the body to lungs etc
7. Surgeon recommendations – would he/she do it for their own dog?
8. Psychological impact for the owner: It is important to understand this is risky surgery, sadly current guidelines indicate 1:5 dogs do not make it, and some recommendations are not even that high. Can you accept it if your dogs dies during or in the postoperative recovery period surgery? This is where it is important to weigh up whether the benefit of your dog being fully cured is worth the risk of possibly losing him.
9. Financially – can you afford it? Find out estimate of costs.
10. Hopefully this will not happen, but if your dog collapses, e.g his heart stops either during his surgery or afterwards what emergency measures should be undertaken, do you want your dog to have CPR, how far are you (the owner) willing to go for your dog to be saved in such circumstances

Part II - Surgery has been recommended as treatment for your dogs adrenal tumour, here are a few suggestions on what questions you should ask your surgeon:
1. Are you board certified? How many operations of this type have you done? What complications have you experienced? What were the outcomes?
2. Please explain to me how you will do the surgery, which part would likely give you the most trouble? Will you be doing the actual surgery or a resident in a teaching situation? If so, is their close supervision?
3. Will there be a specialist anaesthetist available for the surgery?
4. If it hasn’t been done, do we need a CT/MRI scan to look at the tumour more closely to check for vena cava involvement or any other tumour spread?
5. What are the risks associated with this surgery, including
• Bleeding (including trauma to blood vessels or other organs during surgery)
• clots
• Blood pressure or heart problems such as arrhythmias
• pancreatitis
• pneumonia
• kidney failure
• infection
• wound problems
• bowel problems
• anaesthetic risks
• adrenal insufficiency or electrolyte abnormalities
• death (sorry but you have to ask that risk too)
6. If we proceed with surgery does my dog need preoperative treatment with Cushing’s meds, antihypertensive if high blood pressure is a problem – phenoxybenzamine recommended preoperatively for dogs with pheochromocytoma, anticoagulants or anything else?
7. How will you treat to prevent clots postoperatively?
8. What would you do if you found anything else during the surgery i.e. nodules in other organs e.g. spleen, opposite adrenal, liver, kidney. Would you remove them and what are the risks associated when doing additional abdominal surgery together with adrenalectomy
9. How long will it take and when will you contact me so I know all is OK, when can I visit after surgery?
10. How will the postoperative period go, how long would you anticipate he would need to stay in hospital? How will we manage pain?
11. What monitoring would be needed, e.g. heart monitoring, oxygen levels in the postoperative period
12. If your dog has an adrenocortical tumour affecting cortisol production will he need to be on steroids following surgery and for how long?
13. If there are problems when I take him home, who do I contact? Hopefully the surgical team until all is stable.

I'm providing a link to their thread: Flynn 11 y/o Foxie Cross - Right adrenalectomy, 3rd Dec 2012 for Pheochromocytoma (http://www.k9cushings.com/forum/showthread.php?t=4242)

I am sure Trish will swing by soon and share her advice and knowledge. If you have any questions at all please do not hesitate to ask.

Hugs, Lori

djndobby
01-16-2015, 01:22 AM
Thank you ladies. I've already read up on Trish and Flynn's story along with the questions to ask the surgeon. It seemed like a very difficult procedure to go through for both the dog and owner. I'm very delighted to share that his ultrasound done yesterday revealed no growth or vascular invasion. We've decided to monitor every 2-3 months for now. Hope everyone else is doing well!

<3 dj n dobby

Squirt's Mom
01-16-2015, 08:44 AM
I just saw your avatar and had to do a double take! Dobby looks a great deal like my Trinket, who is maybe a Chi mix. She's a rescue and cute as a bug whatever she is! Her coloring is much like Dobby's!

Trish
01-16-2015, 03:05 PM
My apologies! I was sure I had posted on your thread a couple of days ago, but it has not shown up for some reason :rolleyes:

Yes, no doubt about it the adrenalectomy for Flynn was stressful as it is for everyone going down that path. But all that stress was worth it to have him still here with me over two years later, it is only a distant memory now!! Also keep in mind his recovery was much slower because of the swab they left in him. If that had not happened I am pretty sure he would have done very well and bounced back much quicker.

But I think I agree with your plan of watchful waiting to see what happens, have they given you any idea of prognosis on his kidney issues with his BUN, creatinine and phosphorus all raised? I was not sure what azodyl was so did a google and mainly probiotic? Wondering why they have not suggested any other form of reno-protective drugs, or something to manage the high phosphorus.

Flynn also has a 1cm nodule on his remaining adrenal. We have watched it for over two years now, it was present prior to his adrenalectomy. It has not grown and now he is 13 coming up 14 in a few months I seriously doubt we would ever do anything about it. Flynn did have kidney problem before his surgery, protein in his urine caused by the high BP due to the type of adrenal tumour he had. This has not gone away, but we manage it with medication but his blood numbers have not been out of normal range.

So pleased you got good news yesterday!
Trish

molly muffin
01-16-2015, 05:17 PM
Oh isn't he a cutie!

Nothing wrong with monitoring, especially with other things going on.