New to the group! Trilostane - sweet Simba has crossed The Bridge

[Simba's Mom]

Thank you for all the Birthday wishes, Simba is grinning from ear to ear!!
PS Marianne, thanks for changing the number to 11 :)

[Simba's Mom]

Simba has not been himself these past two day, very gassy and tummy looks bigger and gurgling, but poos seem a little better, weird.. He has been shaking and right now is running a temp, but his food intake has been good too..I'm so confused, when he was sleeping last nite he cried, makes me so worried....tomorrow I will start him on the floraflora and I got some pumpkin in the house too. He looks like he is going to throw up but doesn't so thats weird too...I wonder if he should be on something for his liver too?

[molly muffin]

Definitely start the floriflora. Hopefully that will help him out. There is also an over the counter called Gas X.
It's over the counter. Lori gave this link on another thread, which I bookmarked, so I'll pass it on to you too.
http://www.walkervalleyvet.com/otc-meds.htm

You know if he seems too off, to the vet you go. Simba has a sensitive tummy and we all know that. Also, if it looks like he is in pain, you can try the chicken and mushy rice (or turkey if that works better with him, which it might) for a few days, small meals, just like before.

hugs,
Sharlene and Molly Muffin

[Simba's Mom]

Started the florafora lastnite, does it take a few days to work? Also, how do you give it to your pups? thanku

[molly muffin]

Hi ya Letti,

For Molly I sprinkle about a half packet on some wet food in the morning. I put like a teaspoon of wet food on her dry food. When she was having diarrhea, I put half a packet on some wet food twice a day. Right now I only use it if she seems to start having problems and I haven't had to use it for awhile.

Valerie is using every day right now I think, so she can let you know how much she is using and how she is giving it too.

Hope it helps Simba out.

hugs,
Sharlene and Molly Muffin

[goldengirl88]

Hi Letti:
How is Simba doing? Hope it is a nice weekend and all the babies can get outside. God Bless You
Patti

[Simba's Mom]

Simba still has bad poos, also lots of shaking in the back legs, even when he's laying down...I feel so bad for him, he looks at me like "why am I shaking Mom?" His tummy looks bigger at different times during the day and he has fever off and on....not sure whats going on...he has been on the florafora for 3 days....

[molly muffin]

When was his last ACTH test and general blood work? I'm wondering if he is also having some problems with his pancreas again?
Is he eating alright?

hugs,
Sharlene and Molly Muffin

[Simba's Mom]

He is due for his testing again in June, and his water intake and food has been good! Should the florafora be working?

[Harley PoMMom]

Fever with diarrhea are a bit worrisome to me, it sounds like an infection of some kind going on. Simba might need antibiotics, and is he drinking enough because a fever can dehydrate a dog.

Sending healing and loving hugs, Lori

[molly muffin]

Letti, I agree with Lori.
He might have picked up a bacterial infection somewhere along the line, or something else. Either way, that fever isn't good or normal. Every time that Molly has had a fever, it's been some sort of gastro infection or crystals, UTI, something like that. I think you should get him checked out.

hugs,
Sharlene

[goldengirl88]

Lettie:
Just checking in on Simba to see how he is doing today. Hope today is a better day for him. Blessings
Patti

[Boriss McCall]

Good Morning..
HOw is Simba feeling today? I hope the fever is going down.
Boriss does the same thing with his belly. Sometimes it looks bigger. For Boriss it might just be gas.
Hope today is a better day.

[addy]

Hi Lettie,

If Simba still has a fever, he should probably be seen by a vet but I am guessing that is where you are right now.

Hugs and prayers for Simba.

[Simba's Mom]

Just got home from work, Simba is not feverish at the moment but I'm going to call in to the vet...its snowing here in good old Iowa, so I won't be able to bring him to his regular vet in South Dakota :( so hope a phone call there helps!!!
Thanks everyone for checking in on Sim, hey does anyone know how long it takes the florafora to work? thanku

[molly muffin]

Checking in on you and Simba!

hugs,
Sharlene and Molly Muffin

[molly muffin]

Snowing.. Julie mentioned snow at her place too. You guys can just keep it. I am all about spring and summer at this point. lala la a la la la al

It took us about 2 days to see an improvement. I'm wondering though if Sim has a gastrointestinal bug, that would be causing the diarrhea, loose stools and the floriflora, while it will help, is going to need an antibiotic to combat that. I'm sort of thinking Baytril. Valeries Daisy had a dickens of a time getting rid of an infection and Simba's tummy issue seem to come, then go, then come back. So....
I'd keep with the florifora and also get an antibiotic for his tummy, really thinking something along the infection lines that Lori mentioned.
Possible something the vet could call in for him to a local pharmacy till you can get Simba there (better weather).

hugs,
Sharlene and Molly Muffin

[addy]

I found my poo notes on Zoe from 4 years ago when she was on ID and Forti Flora. I had written down it took Zoe a month on the Forti Flora before I saw any improvement. She had been going through her first bout with colitis. Every time I would stop the metorindazole, it would all come back and I could not change her food from the ID to anything back then. So she had something going on and maybe Simba does too so you might not see results in a few days.

[infoviewer]

Hey Lettie: Hope Simba is better this morning. CoCo has a lot of stomach issues also. We do poop patrol every time he goes out to keep him from eating the poop or dead grass or anything he finds in the yard. I am going to start him on the fortiflora. Need to find out where to get it. CoCo also cries in his sleep, I just figure he is dreaming and I just say "its ok sweetie" and he stops. And then again he may be crying because he still has his cone on, his sore on his foreskin is about healed, but not quite, so waiting until I see nothing. Then have to start on his broken toenail or whatever else pops up. Seems like old dogs and especially cushing dogs always have something wrong. CoCo really had weak back legs and still cannot jump up on the couch, but is much stronger and I have been giving him Glucosamine for several months and think that has helped him. I also give him NuVet Plus vitamins, which are pretty expensive 90 for about 70.00 I think. You have to go through a groomer or vet to order them. Just a thought. Wish I could find something to help his hair, but have not as of yet and think it is the cushings along with the hypothyroid or maybe just dachshunds. Just thinking of you this morning. Love, JoAnne

[Trish]

Hi there, gosh I wish Simba could catch a break, poor little pup! Hope it goes well at vet today and you get some support and answers from them. Will be checking in tonight to hear the latest! Good luck! xx

[Squirt's Mom]

Hi Letti,

How is Simba today? Did he see the vet? Let us know when you can.

Hugs,
Leslie and the gang

[infoviewer]

Hope you got to see the vet and Simba is ok this morning. Watching for your post. Love, JoAnne

[Simba's Mom]

Simba is still feverish off and on, I called in and they told me to take his temp, do digital thermometers work with dogs? If it's over 102.5 he should be seen....thanku for checking in on him!! Just going to keep a watchful eye on him!!!

[molly muffin]

I think they do? but I've never tried it myself. Molly is disgusted enough when the vet has to take her temp.

I do think he has an infection. Cushings doesn't cause a fever and neither does the medication that I know of. I think he has to be seen. Maybe not tonight, but definitely as soon as you can go.

Did you get that snow?

hugs,
Sharlene and Molly Muffin

[Simba's Mom]

Hey Sharlene, yes we got the snow, but it's almost all gone already...
I tried the temp thing and Simba had a fit, I don't know if I can do it or not, but have to keep trying...he's eating and drinking ok, but yeah wish he wasn't feverish....thanku

[molly muffin]

How is Simba doing? Did you ever go the vet? Is the florifora helping at all?
We need an update. Having Simba withdrawals here. LOL

hugs,
Sharlene and Molly Muffin

[Simba's Mom]

Simba is still feverish at times and refuses to let me take his temp, it also seems like his glands are expressing alot, he just got a groom last week and they were expressed by groomer...but everyday he is licking his little rump, its confusing to me whats going on, his ears are red also so I have drops for those...thanks for checking in with us! Hope your pups are doing well too :) the florafora seems to be working yay!!

[SoggyDoggy]

It really does sound like an infection to me. If the temp has been going on this long and now you are seeing discharge :eek: (and that can't smell good either). Did the vet say anything about an infection or antibiotics at all?

Poor Simba, not nice that mommy tries to shove things up his bot.:o

[Simba's Mom]

my vet just said to bring him in if his temp gets too high, but I think I will call again tomorrow....thanku

[goldengirl88]

Letti:
I hope your precious Simba starts feeling better, it sounds like he does have an infection. God Bless You Both
Patti

[doxiesrock912]

I'd bring Simba to the vet. With Cushings messing with their immune systems, I wouldn't take the chance of waiting any longer.

Hope she feels better soon!

[Fellasmom]

Hi Letti
Just wanted to thank you for all your love and support.I'm just starting to read thru all of the threads posted here.Just wanted to say hello and big hugs to you and Simba.So unfair all these babies have to deal with this disease!Lots of love sent your way and thanks so much your kindness,especially when you are dealing with so much with Simba!
Love,
Patty

[Budsters Mom]

Hi Letti,:)
Thank you for your very sweet message. :)
How is Simba doing today? Is he still running a fever? Yes, I agree with the others, it does sound like an infection, especially with the discharge. Did you get a chance to talk to the vet today? I hope he's feeling better real soon.

Sending many hugs and wellness thoughts your way,
Kathy and Buddy:)

[Simba's Mom]

Simba's fever is gone, so thinking it might have been the ears, I have been putting drops in...and since starting the florafora his poos are better but he licks his butt all the time, so thinking his glands are expressing? Anyways, thanks for checking in....take care
Patty, you are so sweet checking in when you just lost your baby, you have helped so many so thanku for all you do for us!!!
Valerie, I always enjoy your thoughts cuz u have a doxie too, thanku....
and the rest of you angels, thanku for all your help thru this journey, I'm trying to get to know you all and your furbabies, you are all so special to me!
Hugs from me and Sim

[doxiesrock912]

Good news Letti!

[Mel-Tia]

Hey Letti

Just wondering how you and Simba are? I saw a Doxie while I was out walking and it made me think of you guys and the others we have on here!

Hope you are both doing well?

Big hug, belly rubs for Simba

Mel
Xxxx

[molly muffin]

And how is Mr. Sim doing? Has his tummy issues cleared up yet? Do you think the floriflora is helping?
I haven't asked how your husband is doing either. :( I hope that things are looking up with both him and Simba and that You are getting some rest yourself.
Don't think I have forgotten how you worry about everyone else. (and for good cause I admit) but I don't forget, so I hope you are doing fine yourself. :)

hugs Letti and an ear rub for Simba
Sharlene and Molly Muffin

[Simba's Mom]

Hey Mel and Sharlene, Simba is doing ok, thanks for checking on him..his poos are much better, he still takes the florafora stuff, weird name for poo helper :) and his tummy doesn't gurgle, so I think he feels better that way too....my hubby is doing better too, his heart is know working 35% instead of 25% so we are very thankful and praying it continues to heal....thanks again!

[doxiesrock912]

Great news Letti!

[goldengirl88]

Letti:
I am so glad to hear both your husband and Simba are improving. I bet you are happy to have some good things happen! God Bless All Of You.
Patti

[Trixie]

Yay! Sounds like Simba is doing really well! Glad to hear your husband is also doing better!! Good news all the way around. :)
Barbara

[Boriss McCall]

So glad you husband is improving & only getting better.;)

[Squirt's Mom]

More good news this morning! I am so happy things in your house are looking up at last, Letti, and I pray the trend continues for you all.

Hugs,
Leslie and the gang

[Simba's Mom]

Thank you everyone, praying for your pups too, oh to have normal days :)

[molly muffin]

Yay Letti! That is great news about husband heart And Simba. Hope they both continue to improve.

hugs,
Sharlene and Molly Muffin

[goldengirl88]

Letti:
Thinking of you, Simba, and your hubby. Hope things continue to go up hill for you all. God Bless
Patti

[infoviewer]

Yahoo Lettie, some good news for both Simba and your husband. Hope we continue to get good news down your way. Love, JoAnne

[Simba's Mom]

Happy Mother's Day Everyone!

[goldengirl88]

Letti:
Happy Mothers Day to you too! I hope Buddy and your husband are still improving. God Bless You
Patti

[molly muffin]

Happy Mothers Day Letti!

sharlene and molly muffin

[Simba's Mom]

Simba had an off day today, he woke up whining and just was not himself..I had to beg him to eat, but he drank more water then usual..His walk turned into me carrying him and his back legs are really weak and shaky, I feel so bad for him...I better get him into the vet next week.....take care and have a great memorial day weekend, praying for all of you and our pups...

[Budsters Mom]

Hi Letti,:)
I am so sorry to hear that Simba has been feeling so poorly. Please get him into the vet ASAP. Something is going on there. Yes, I feel bad for him too.:(Our babies can be so worrisome at times. Sending you big hugs, prayers and lots of love.

Kathy and Buddy:cool:

[goldengirl88]

Letti:
Sorry to hear Simba is not feeling well. How long has it been since he had an ACTH? I always am suspect of cortisol rising when Tipper starts with the excessive drinking. Maybe a trip to the Vets is in order? Tipper has had a few days like that lately. She had not been herself, but this morning she wanted up at 5:30am and I got up with her. She seemed real ready to have some fun, so maybe she wasn't feeling well prior to this. Good Luck, and tell Simba to feel better. Blessings
Patti

[molly muffin]

Oh poor Simba. How is the stools looking? I hope that Simba starts to feel better. Why do things always come up on the holiday weekends?
You know every time I've ended up with Molly at the ER it was on a holiday weekend.
Okay Simba, paws up, lets get you feeling better so momma can have a good weekend with no worries. :)

hugs,
Sharlene and Molly Muffin

[Trixie]

I hope Simba is doing okay. I hate when stuff happens on holiday weekends! :mad: Hopefully Simba is a little perkier now and you can get him in to the vet next week.
Barbara :)

[Budsters Mom]

How is Simba feeling today? I am hoping that she just had an off day? I am feeling a little bit like that today myself. ;) Please keep us posted. Thinking of you both.:p

Kathy and Buddy:cool:

[Trish]

Awwww hoping Simmy is feeling better today, poor little pup! Perk up boy!! xxxx

[DoreneT]

I agree, try to get him to the vet soon:) This group is so supportive and wise:)
xo
Dorene and Tucker

[milosmom]

hey letti i am so sorry to read that simba isn't feeling so good.i am sending you prayers and healing energy...simba reminds me so much of my milo....hang in there sweety we are all here for you !!! patty(milo)meka xoxox

[doxiesrock912]

Awww Letti,

poor Simba! Maybe he just strained somethin? I hope that's all it is.

[Simba's Mom]

Today Sim was about the same, he ate better so that was a good sign, but when he insisted on a walk he didn't make it again and this time he would walk and then his front legs would give out and he would take nose dives, this is so hard to watch, maybe the end of his walks...So I carried him home and he loved that :) His back legs are bad, usually he tries to jump off my lap then I help him down, for two days now he has whined instead of even trying to get down, good thing I know what he wants...we have to go to see our son over the weekend so I have a good friend who loves Sim as much as me, watching him...I will call the vet as on Tuesday and hopefully bring him in, today I had to get flowers ready for Memorial day, such a sad day sometimes....take care and have a great Memorial Day....also thanks for checking on Sim.....

[Tina]

Hi Letti,
Sorry to read that Simba isn't feeling the best. When was the last time you had a stim test? I am wondering about possibly low cortisol since his appetite isn't the best and he's having trouble walking. Thinking of you both and I hope he feels better.

Hugs,
Tina and Jasper

[goldengirl88]

Letti:
Sorry to hear about Sims legs. I think the day that happens to Tipper will be the most devastating event to her. She treasures her walks and lots of them, so the day she can no longer make it will be one sad day. That is about all she has to look forward to besides watching the llamas on the farm, so if that is taken away I think she will really mentally deteriorate. Try to keep exercising his legs while he is in your lap. One of the really bad aspects of this disease is the muscle wasting. After they start getting weak, then they don't want to use them anymore, which just compounds the problem. When Tipper sleeps and I look at her body I can hardly believe it is the same dog, so much of her muscle has wasted away. God Bless you and Simba and your Hubby
Patti

[Simba's Mom]

Simba is at the vet overnite, his front legs have been bothering him for 4 days in a row, since I live about an hour away, they will do the acth test tomorrow morning, then I can pick him up around 1pm or so...I took his trilostane along just in case, so glad I did....Simba cried the whole way up to the vet and would not lay down, so I'm glad he can just stay there overnite and hopefully be fine....He was settling down when I left, and his vet is the best so felt ok leaving him...I felt so dumb at the vet cuz I cried, ugh wish I was better but just the way I am I guess...I thought his fatty lumps were harder so I was worried he had cancer, the vet said she didn't feel anything bad, so I was very relieved, of course I cried when I left him...I will know results on Thursday...

[addy]

Oh Lettie,

I am so sorry Simba has to stay at the vets. I hope they can find out what is wrong. Of course you cried, I would too, how could you not?

Sending much love and saying many prayers for Simba.

[molly muffin]

Oh Simba! Is his front legs just giving out on him? What did the vet say about that?
I'm with Addy, how could you not cry. I bet they are limpoma's. Fatty, and nothing to be worried about. The vet would have opted to aspirate to check if worried I'm sure.
Hopefully the ACTH will be good results, Just have to figure this all out. Did you tell the vet about the ongoing tummy issues too? Just so they can look into that as long as he is there?
Hang in there Letti! I know it's rough. I hate nights at home without molly too.

hugs,
Sharlene and Molly Muffin

[goldengirl88]

Letti:
Don't worry about crying at the Vets office, I have become such a cry baby since Tipper got Cushings that I can do it instantly just thinking about things. There is no shame in showing your love for your sweet Simba, more people should get the message on how to treat animals. I hope Simba does well and is happy to see you today. What did the Vet say about the front legs? Blessings
Patti

[Trish]

Awww Letti, I hate hate hate saying goodbye at the vets even if I am only leaving him for a couple of hours. They always tell me he settles down pretty quick after I leave, so I have learnt to make a quick exit so not to prolong the anxiety for him and me :D:D Sounds like Simba is in good hands with your vet so that must be a relief for you.

Hope his testing goes well and they have some answers for you today!
Trish xxxx

[frijole]

Prayers sent for you and your baby. Hoping the acth tests are good. Kim

[milosmom]

awww letti,we all understand your heartbreak and tears,we unfortunately can relate to this stressful situation...sending healing thoughts,hugs and lots of love to the two of you....come on Thursday ! patty(milo)meka xoxox

[Simba's Mom]

I got my Sim back, I missed him so much and it was only one night, but he's my little buddy so life is good again!:) The vet will call me tomorrow with the acth results, hopefully it's just a med change...thanks so much for your prayers, I will post when I know more....bunches of love to all of you, couldn't do this alone!

[Budsters Mom]

Letti,
I am thrilled that Simba is back home with you!:) Saying goodbye at the vets is cruel and unusual punishment!:eek: Hopefully his meds will just need a little tweaking.

Sending love and hugs to you both,
Kathy

[molly muffin]

Yay, so glad Simba is back home with you. It is horrible when they aren't there. House feels different, empty or something.

hugs,
Sharlene and Molly Muffin

[goldengirl88]

Letti:
I am so glad your baby is back home. Tipper has never been away from home overnight. I cannot even think of her not being home with me even one day as that is how it has been for the last 11 1/2 years for us we are never separated. I hope you and Sim get good test results, and that his legs start working ok again. Blessings
Patti

[addy]

I'm so glad Simba is home, Lettie. How are his front legs?
I have not been away from Zoe overnight in five years, I probably would not sleep.:o:o:o Now that I think of it, five years ago when we were away for a week and my friend took care of her, I did not sleep the whole vacation:rolleyes::rolleyes::rolleyes:

I know every dog is different and I dont know what you currently feed Simba, but recently I switched Zoe's probiotic and took away most of her chicken treats and replaced them with small pieces of boiled skinless white potato and after two weeks of potatos, her poo firmed right up and is a nice brown. I think the potato helped her. I thought I would mention it to you. Also, my old holistic vet said green beans can firm up poo but Zoe could never tolerate them.

Have a good day with your little boy:):):):)

[Simba's Mom]

Hi Addy, Simba eats Blue Wilderness turkey and potato kibble, also some of the same flavor canned...he also takes Floraflora, seems to be helping...Simba is over weight, I'm afraid if I fed him potatoes, he would gain more weight, but I would love to try it....once I start feeding Sim 'human food', he thinks he's the king and he won't go back to "dog food" without a good old fashioned fight! Oh wait, he is the king of the forest, I always forget, but he reminds me daily....:)
His legs are about the same, but I haven't taken him for his walk yet, I do believe it's good to keep him walking, but we will go for 2 short walks instead of one long one, vets advice!

[Budsters Mom]

Of course Simba is the King!!!!:D How could you possibly forget that even for a minute. Our babies are nobility, while we are their lowly subjects, ready and willing to serve!:D;)

Hugs,
Kathy

[Simba's Mom]

True that Kathy:), I just got his results in and is number is 5.9 in range she said.....that being only one test, so kinda confused, thought they always do two blood draws....so I took Sim on a short walk and now he has the runs, so I don't know what to think, I'm totally confused today...But his front legs didn't buckle once, so to me that is good....so if he gets worse I have to bring him in, the vet said I could put him on pain pills for awhile but I opted not to...please help me understand...

[molly muffin]

hi Letti, It depends, if she just gave you the post number or if they only did a base cortisol draw. Which makes no sense, but it happens sometimes.
At 5.9 if that is the post number on the ACTH test, then he would be okay, if no symptoms. If still having symptoms, then he could go a bit lower still, to under 5.
Molly has been known the get the runs by the end of a long walk. She starts out fine, then she'll have a poop somewhere, then a ways later, do it again, only this time more runny than firm. It's strange I guess, but she's always been like that. It's like walking just loosens everything up.
Well, if his legs go out then he might need to lose weight or he could be having some arthritic issues.
Just keep an eye and see how he does.
hugs,
Sharlene and Molly muffin

[Budsters Mom]

Letti,
Buddy's front legs buckle too. :(When this happens he does a face plant. OWWWWW!!!!!!!:eek: :eek: His neuro problem are much more obvious now. Buddy's leg issues are directly related to that. Has Simba ever had any kind of neuro testing? Just a thought....

Hugs,
Kathy

[Trish]

Flynn can be like Molly and Simba too, with it getting looser on a walk. Is weird how that happens but I think of it like Sharlene does with it all getting loosened up :D:D Hope the walk when well today and the King of Jungle is doing just fine. xxxxxx

[Simba's Mom]

Hi and thanks for checking in, you gals are the best! I took Sim rather "The King of the Jungle" for a walk again today, he slowed down toward the end but no face plants...yay, seems to be better today...poo is better too, I never thought I would watch Sim poo as much as I do, seriously this cushings has done a number on me too...I need to worry less and just enjoy everyday with my Sweet Simba, easier said then done....:p
Hugs and prayers to you all and your furbabies too!

[Trixie]

So glad Simba is back home! I am with you Letti...I hate having that overnight at the vet. It always feels so good to pick them up and get them home! I didn't even like leaving Trixie for her acth test the other day and it was only a couple of hours! :rolleyes: Hope Simba is doing fine tonight. ;)
Barbara

[Trish]

Yay... good poop (tick), good walk (tick!) Sounds like a good day in the King of the Jungle's household, hoping for another one today. Have a good weekend Letti! xxx x

[Budsters Mom]

A walk without face plants is a good day! Way to go Simba!!:D

Hugs,
Kathy

[addy]

A holistic vet explained to me her some years ago with Zoe that the longer the stool stays inside of them, the firmer it will be, so if the pups go for a walk and keep smelling good smells and they keep pooping because of the great smells, it will be softer because it is coming out sooner than it should as they are marking from the smells and not to worry about it.

That was her take on it, not sure if she is right;););)

Happy Sunday!!!

[Simba's Mom]

Thanku ladies, yes face plants on walks, no fun for Simba, he's doing quite well today, just sleeping in the sun and opening his eyes once in a while, doesn't want to miss anything...and yes I bet the "The King of the Jungle" is marking his territory, some dogs pee, guess Kings poo...thanks again for the encouragement, you are all so special to Simba and me too....

[molly muffin]

Kings poo!!! ROFL! Simba! LOL
So glad he is feeling better and having a nice day in the sun.

hugs,
Sharlene and Molly Muffin

[Budsters Mom]

Of course kings poo! They have lowly servants to clean it up for them! LOL:D So glad that you both are having a great day!:D

Hugs,
Kathy

[Budsters Mom]

Dropping in to send love to you and Simba. I hope the king of the jungle is doing well today.:);)

Hugs, Kathy

[goldengirl88]

Letti:
Hoping Simba is doing well after his stint at the Vets office. Tipper is sending the King some kisses. Blessings
Patti

[Simba's Mom]

You guys are making Sim's head swell even more lol, we have to laugh or we would be crying all the time...Simba was holding his own for a few days, we went on half walks, with no face plants, then today he didn't want to go at all, but I know walks are good for him, so he went and then I carried him half of the way, he just had no bounce to his steps like normal....Even when I put him on our lawn to run up to our house he didn't want to walk, so we will see what tomorrow brings....his body has been shaking more, not sure if its the meds, just makes me sad when he's not feeling up to par....he eats fair and his poos are fair too, I so wish we didn't have to watch are precious pups struggle.....take care everyone and lets pray they find a cure soon....

[molly muffin]

Awww poor little Simba. At least he made it part of the way. Molly has been known to decide to lay down under a tree and noy want to move. Then I'll pick her up and carry her for awhile, till she gets squirmy and wants down. I'm convinced all it takes is walking past one of her trees and her sniffing a postcard left by another dog to make her find her energy real quick. I wish Simba would do the same, it's really funny when it happens.
I wish we knew what makes Simba shake like that. I have read on here of cases where the vetoryl does that.

hugs,
Sharlene and Molly Muffin

[Budsters Mom]

Letti,
We all have off days sometimes, let's hope it's just that. Yes, our babies are worrisome little critters. The shakes are really scary. I do know how you feel, because Buddy's head tremors scare me. Give the king of the jungle a belly rub for me. After all, he needs to remain strong to rule his kingdom.;)

Hugs,
Kathy

[Trixie]

Oh..sorry to hear that Simba wasn't having a great day. Hoping he is feeling better tomorrow.
Barbara

[Trish]

I too hate the ups and downs... poor wee Simba, not like him to be on a go slow... hope he has perked up tomorrow Letti. :) xx

[goldengirl88]

Letti:
Sorry to hear Sim is having some bad days. Maybe he is just going to have a few off days. When Tipper does this, I start jumping to all kinds of conclusions because this Cushings is so unpredictable. Hopefully it will pass. I think sometimes it is the affect of the physical changes in their body from this disease. Hope the king perks up! Blessings
Patti

[addy]

Hi Lettie,

They get tired out faster. Zoe went to the GP yesterday. Between the car ride and vet visit, she came home, had her dinner and just was knocked out. I had to wake her up for her snack at 8pm. I think changes in their routine that they used to take in stride really tire them out now. Their little bodies cant make the cortisol needed for stressful events.

We do the walking one day on one day off. The off days are mini walks. Even on her bath day, I cant do both the bath and a long walk. Maybe try one day on, one day off for walking for a week or two and see how it goes.

When was Simba's last ACTH test and what were the results?

Hugs and prayers

[Simba's Mom]

He just had a acth test only one draw, not so happy with vet right now... it was 5.9....sorry just having some down days, thanks everyone for checking in...

[Budsters Mom]

Letti,
Why did the vet only do only one draw? What kind of an ACTH test is that! :confused: We all feel down sometimes. It comes with the territory. Sending you and the king of the jungle, lots and lots of hugs and love.
We're here for you:)

Kathy

[goldengirl88]

Letti:
I think I would be calling back to the vets office, and wanting an answer on why only one draw. That is worthless and puts poor Sim thru the torture for nothing. There is no excuse for this, they need to be held accountable. I hope they did not charge you the full amount- I wouldn't even pay for a test that is useless! The king of the jungle deserves better than this! Blessings
Patti

[molly muffin]

1 draw is just a base cortisol reading and doesn't give you the post number. They do it without the agent being used. Some vets seem to want to do this to just monitor what the cortisol within the body is. Did they give you the base number yet by any chance? However if you wanted an ACTH test, that isn't it. ACTH specifically uses the agent to cause the body to dump and then you draw an hour later, after the dump has happened to see how much they are making and storing in the body.
If you requested an ACTH then for sure, call the vet and find out why they didn't do one. Sheezzz some vets, just make things harder for us to monitor what is going on. With the problems that Simba had had off and on, I'd have wanted to know what the post number was too, so you can make an informed decision on treatment.
Protocol vets, protocol, follow it!
Hugs Letti!
Sharlene and Molly Muffin

[Simba's Mom]

Simba's post number is 5.9 one draw...my vet uses pills, does any others use that? Thanks
They said they would only charge me for one draw.....

[Budsters Mom]

Letti,
They should be paying you for putting Simba through that and apologizing to Simba,:mad: I have never heard of pills for an ACTH test. At my vet they do a pre-draw, inject the solution and then they do a post draw one hour later. I go and stay with Buddy. They give him the pre-draw and the solution. Then they bring them out to me to sit with me for an hour. After that, they take him back for the post-draw. I always stay because I can't count on them to do it within the required time frame. I hope some of our experts can help you with that pill thing. I'm not sure what's up with that!:confused:

Great bigs hugs to you and the king,
Kathy

[Trish]

Hmmm that certainly does sound strange. Hope you have got to the bottom of it and a refund would be nice! Hope Simba is doing well this week and enjoying the summer and hope its not too hot for him!! Have a good week and get those vets sorted out on the right path as per the experts here!!

[goldengirl88]

Letti:
I agree with Kathy. I never heard of pills, and I would be wanting a refund too. This is hard enough on the poor babies, but then to not have results you can't use is terrible. I do the same thing as Kathy. I stay there with Tipper and sit with her in between for an hour to make sure they do everything on time as my vet gets busy, and really isn't efficient. I have to be the babysitter and make sure all is done correctly, as when they make mistakes at my vets, they tend to cover their butts instead of telling you. To eliminate all this, and make sure Tipper is ok I just stay, as they know I won't put up with crap from them. God Bless you and Sim you two don't need this. Patti

[molly muffin]

How is simba doing? Hope all is going well.
hugs,
Sharlene and Molly Muffin

[Simba's Mom]

Simba is doing the same, no walk today too hot for him, it's like I wonder if I should treat him, find new vet, what do I do? Just lots of things going thru my mind, thanks ladies for checking in......

[KennyJ]

Letti, you sound like me. I have been told so many different things by so many different vets that I have lost trust in all of them. Even when it comes time for me to test Gracie I still don't know who I will use.

[molly muffin]

It's hard to know what to do and who to do it. I wish your vet had done the complete ACTH test. Did you talk to her about that? Why they only did one part and not the post draw? The last result I think I have for you is from January, 2013 and then the pre was 3.1 and the post was 6.7. Which isn't bad if the symptoms are controlled. Now though if the pre number is 5.9, I'm guessing the post number has probably gone up too.

Did the vet say what she thought of the 5.9 pre number? I don't know if that is affecting how Simba is doing or not though. Could be. When was his last cbc and urinalysis? Just to know how his levels are doing.

I know you are already driving an hour to get to this vet. How comfortable are you with her? Do you feel like she is the best for Simba? I just want to get a take on your feelings about it.

Are you giving Simba any liver support supplements? How about glucosomine for joints?

Hang in there Letti. We'll get it figured out. Simba had a history of a tempermental gastric tract too, so that might play a part in this too, it's all a very fine balance and what is a good number for one dog may not be the best for another. So what I am trying to say is we want to find what works best for Simba and keeps him as king of the castle. :)

hugs,
Sharlene and Molly Muffin

[Simba's Mom]

Thanks everyone, new vet tomorrow for Simba, I just have to go somewhere different....guess we are starting over but what else can I do, I love Sim so much and only want the best for him.....

[Trixie]

Letti- Hoping the new vet works out for Simba and ends up being someone you can have some confidence in. Let us know how it goes!
Barbara :)

[molly muffin]

Take copies of tests with you. Is this one closer? Did you ask them all the questions, have they treated cushings, how many, what drugs do they use, what about the testing protocols, etc?
Hugs Letti. We all just do the best we can.
Sharlene and Molly Muffin

[goldengirl88]

Letti:
Glad to hear you are getting Sim a new vet. I think it is the best thing to do with what has happened. I would also use caution and ask about this vet and see how many times he has treated Cushings, as you don't want to repeat the last situation all over and spend more money and not be satisfied. Praying this works for Sim. Blessings
Patti

[infoviewer]

Good luck Lettie, hope you find a vet that can help Simba. These mini-doxies seem to have a lot of problems. My CoCo is so skinny and weak, but just keeps trying. I think the weakness goes along with the cushings since they lose their muscles and fat evidently. I can see CoCo's spine and feel his ribs. I know it is hard when you see Simba slowing down and not able to do what he used to, but maybe a new vet will have a better treatment for him. It would be nice if someone would find a medication to get rid of this terrible disease for dogs and humans. Love, JoAnne

[Budsters Mom]

Hi Letti,
What time is the appointment, because we're all going with you!;) I hope they have a huge waiting room!:(;):D

Love and hugs to you and the king,
Kathy

[Simba's Mom]

Thanks everyone, appt is at 4:20, I will leave now to start picking everyone up lol, you are the best, just so you know.....when I called this place I asked specifically if they treated cushings, the receptionist told me that the vets there graduated at the university of Iowa, and every vet knew about cushings, yay, and treat many dogs there for that so it already feels better to me. It's not quite an hour drive actually closer so that's nice too...she then took lots of information from me and told me to take sims records along...so I hope I have what I need...I will let you gals know, and you lucky ones that fit in Tahoe, you will know firsthand....hope they know what they are in for, feeling confident about what I know, you have all helped so much, thanks again....plz pray for sim these trips get him so worked up, thanks......

[addy]

Lettie,

I just know you will get some valuable insight for Simba.

Hugs and prayers and I bought a whole pile of Little Debbie's so we have snacks in the waiting room.:):):)

[Budsters Mom]

I'm ready now! Drop by and get me first, ok? I hope they realize that the King is on his way!;)
Hugs,
Kathy

[molly muffin]

Eeek. I'm late but in here too!! Hoping for some good news!
Hugs
Sharlene and Molly muffin

[Simba's Mom]

You guys give me happy tears, you are all the best!!!
I saw a great vet today who has ties with an ims, he told me so much about cushings and showed me signs on Sim etc...in fact Simba was content to let the vet do anything he wanted, and gave him kisses....maybe Simba knew this is what he has been waiting for and that now he would get the right help...I just cried with relief and knew Sim was in good hands......He is staying overnite and will have several tests tomorrow, including xrays, blood work and acth testing...I can pick him up tomorrow so hope he has a good nite, thanku all for the prayers...and the treats in the waiting room, unfortunately this was a much larger place so I had to share:)

[molly muffin]

Oh Letti!!! Super big hugs!!! I know how much you hate for Simba to be gone and totally get that, but I am so glad that you have found a vet who knows about cushings and that you feel comfortable with. We'll want to know all the details you know. :)
Did the vet give you any of his initial thoughts? Dosage? the chronic problems with the tummy, etc?
I know tons of questions. :)

hugs,
Sharlene and Molly Muffin

[Budsters Mom]

Letti,
I'm so thrilled that this vet seems to know what the heck he's doing!:) It is awesome that Simba was so comfortable around him! I know it's hard having him gone tonight, but it looks like he's in great hands. Finally some answers will be on the way! Such happy news for you and our king of the jungle.:D

Hugs,
Kathy

[doxiesrock912]

Letting, finding the right vet is the hardest part. I'm so glad that you are finally on the right track! Dogs can sense so much. The IMS office is the only place where Daisy doesn't shake and head straight for the door:-)

[infoviewer]

Lettie so glad you found a good vet and now you are so sad because Simba is spending the night away, but it is a good thing. Give Simba many kisses this morning when you see him. Love, JoAnne

[goldengirl88]

Letti:
Tipper and I are overjoyed for you and Sim. They say dogs can sense things so your Sim knew he was in good hands. Thank God you both will finally get the help and treatment Sim deserves. The king of the jungle is going to be back before you know it. Blessings
Patti

[Budsters Mom]

A great big hug for the king today.:) He's sure to be tired out after his busy night. I hope to docs are able to customize the perfect plan for our ruler. ;)
Hugs,
Kathy

[Simba's Mom]

Yay, I got my Simba back!!!! The blood work should be back on Monday, the vet was awesome!!!! They also have a great vet tech who went in early to give Simba a walk!!!! They did a xray of his abdomen cause its larger again, his spleen is enlarged and has classifications from the cortisol, thats where the extra is going...they also found a spot on his liver so if we can't get him to feel better we will look further at that but vet didnt think it was a concern at this time! I'm so happy with this vet, and most importantly Simba aka "King of the Jungle" is too! Thank you for your thoughts and prayers, praying for your fur babies too...
PS We will be doing a diet change, maybe more thyroid meds and prob less mg of cushing meds, see what the blood work says....feeling very positive and guilty that I didn't bring him to the right vet before, poor little guy got so run down, I just pray we can get back on the right track...

[Budsters Mom]

All hail loyal subjects. The king has returned!!!!!!! Great news Letti!:)
Hugs,
Kathy

[molly muffin]

Yay, Simba is home.
Don't be too hard on yourself Letti. It's hard to find the right vet, the one that fits with what is going on, that you feel good about and that Simba is comfortable with. Those are all criteria that doesn't sound difficult but can be very hard to find.

Sounds like a lot going on. Have a wonderful weekend. Now you can breathe a bit better. :)

hugs,
Sharlene and Molly Muffin

[goldengirl88]

Letti:
It means so much to be able to trust your vet. I am glad you made the move and got a new one as Sim will only benefit from it. I bet you are so glad to have him back home. God Bless You Both
Patti

[Trish]

Hi Letti

So pleased to read your good review on your new vet, phew what a relief. It makes such a difference to get someone that is on your side and not just for the money! Fingers crossed for good results for Simba (still think of my angel cat Simba when I read his name!) he was the kind of cats too and a great hunter!!

Have a good weekend now your baby is home in your arms! :) xx

[Budsters Mom]

What is happening with the King today? Any news on his tests?
Hugs to you both,
Kathy

[Simba's Mom]

Just got home from work and thought I better check in, anyways, my new vet called right away this am...He said the blood work looked good on Simba, he thinks the trilo is working too good, so we are going off for two weeks and taking 5mg of predisone instead..he wants to see how Simba is feeling in a week then we will go see him and talk about everything including diet...I feel very good about this vet, and seems like Simba does too....thanks for your prayers, hopefully better days ahead for Simba....and if "The King of the Jungle" is happy, everyone is!!! Thinking and praying for all your little furbabies too!!!

[Trixie]

Letti-Sounds like things are moving in the right direction with Simba! So happy you found a vet that you feel good about! :D
Barbara

[molly muffin]

Things are working too good? As in his cortisol has gone too low and now they are putting him on predinsone because he is having an Addison's crisis? That is usually when they give prednisone to a cushings pup. Did he give you the actual numbers? I'd be very interested in knowing those.
I do feel better about this vet I have to say, especially if after the blood work and ACTH test, this is what he has said.
Remember you have to wean off prednisone and can't just stop it. It has to be stepped down.

hugs,
Sharlene and Molly Muffin

[Simba's Mom]

I will call there tomorrow and have them fax me the results, he had acth test too...and then I will send them to post...you gals always have so many good ideas, thanku! Oh, and he did mention addisons, so thats why we are stopping the trilo, it went to low...

[Trish]

Good idea Letti, you know how we love numbers :D Fingers crossed Simba's new vet has got to the bottom of it all and he feels a lot better with treatment! :)

[Fellasmom]

Hi
Just wanted to pop in and say hello.Hope you and Simba are having a good day.Just catching up on the threads here and good to hear that you found a good vet that you like and trust.That's half the battle sometimes!Keep up the good work and hugs to you both.
Patty

[Budsters Mom]

Well no wonder the king has been feeling out of sorts! I'm glad the doc figured out the problem so Simba can continue to rule! The Addison's possibility is a little scary.:o Please post those ACTH number ASAP. We all do worry about our King!
Hugs to you both,
Kathy

[addy]

We will all be waiting for the test results. Hope Sim feels better real soon.

[Tina]

Hi Letti,

Were Simba's electrolytes checked also? If so, get a copy of those results too. When the cortisol goes too low, the electrolytes can get out of wack also. I will be watching for the stim tests results as well. Poor little guy, no wonder he hasn't been feeling well. How long is your vet recommending that he get the prednisone? It sounds like he is to get 5 mg daily for a week and then re-evaluate, is that correct?

(I am posting on the fly from work on my phone so may need to check in later). :rolleyes: I hope he is feeling better real soon.

Hugs,
Tina and Jasper

[goldengirl88]

Letti:
I think it is a good idea also to get the numbers on the electrolytes. That can make them feel really bad too. I am sure this new Vet will get it all worked out, as he seems to be on the ball with Cushings. God Bless
Patti

[molly muffin]

OMG Letti,
Simba is NOT Addison and not in crisis. His Pre is a bit low and stopping and lowering the dose would probably take care of it. His POST number is perfect.
The vet didn't read the notes that was written right after the results.

06/12/2013
ACTH
Pre 1.03
Post 4.2 LOW this appears to be based upon (8 - 17MG)
which is NOT low for a trilostane treated dog

On the test results it says:
POST - TRILOSTANTE: Pre & post cortisol leels between 1.5 - 9.1 ug/
optimal control

These are the items on blood and urine that are high/low
ALKP 878 (5-131U/l) HIGH
Calcium 11.8 (8.9 - 11.4mg) HIGH
Neutrophils 79 (60 - 77)HIGH
Eosinophils 1 (2 - 10) LOW


URINE DARK Yellow color
Appearance Hazy
Sepcific Gravity 1.032 (1.015 - 1.050)
Protein 3+
*urine protein:creatinine ratio testing is recommended
(if the sediment is inactive) to help determine
the significance of proteinuria.

Microalbuminuria >30 HIGH mg/dl


MA is greater than 30mg/dl indicating overt albuminuria.
A.P:Cratio suggeted to quantify the proteinuria.
Microalbuminuria (MA) usially indicates compromise of the glomerularbarrier
and is a significant finding when it is persistent (2 or more
positivet results obtained 2 or more weeks apart).
Persistent MA, in the majority of pets is due to ernal injury secondary to other
systemic disease or primary renal disease. Systemic disease associated with persistent
MA include inflammatory disease, chronic infections, metabolic disease (hypertensitons,
cushings's, diabetes, hyperthyroidism) and neoplasia. False positives results may
occur with pyuria and gross hematuria.
Suggestions for evaluatging patiens 1: check for and treat underlying
diseases indicated above 2: Recheck MA in 2 - 4 weeks 3: in the absence of underlying disease
monitor for progression of MA and development of renal failure

Post T4 6.1 (3.0 - 5.0 mg/dl) HIGH

I just got home and saw your email and so am translating this now for you.

Please call your vet asap and have them review the test results.

hugs,
sharlene and molly muffin

[Simba's Mom]

Thanku, sorry I forgot you had a funeral till after I sent it to you, I'm so sorry for your loss....

[Budsters Mom]

Hi Letti,
I can't really help you much when it comes to the test scores, so I'll just send tons of hugs instead. :)How was the king today?
Kathy

[doxiesrock912]

Letti,

Sim seems to be doing great :) So happy to hear!!!!

[Simba's Mom]

Simba seems to be doing well, not sure what all those numbers mean either, the vet did say to watch for addisons, not that he had it, sorry I didn't explain that better....I'm not sure what to ask him to do next, Simba has an appt next Monday....thanks for hugs!!!

[Trish]

Pleased to hear he is doing good! Is he still on the Prednisone with those numbers? Hope he keeps on the improve!! :)

[labblab]

Oh Letti, I had such high hopes for the new vet but I agree 100% with Sharlene that it makes no sense to be giving Simba prednisone for two weeks when the only issue is that the "pre" ACTH result is a little on the low side but the "post" ACTH result is perfect at 4.2! Not only will his Cushing's be totally uncontrolled during this time period, but adding 5 mg. of prednisone on top will likely cause a fierce rebound of symptoms. Even if Simba was truly Addisonian, 5 mg. sounds like a lot of prednisone for a mini-doxie. For instance, approx. 2.5 mg. would be the rescue dose for a dog weighing 20 pounds. Plus, you cannot give predisone daily for two weeks and then just abruptly stop it -- the dog has to be weaned slowly.

With those ACTH results, I agree with Sharlene that I believe the most that would be recommended, if anything, would be to discontinue the trilo for a couple of days and then start back at a slightly lower dose. I am also concerned that Simba's thyroid level was above normal. His dose of thyroid medication may need to be altered.

I strongly, strongly encourage you to call Dechra, the folks who make brandname Vetoryl. They have vets on staff who are very nice and who can discuss Simba's ACTH results with both you and your vet. I will be very, very surprised if they think that it is a good idea to give Simba predisone instead of trilostane for two weeks. I think it is very important that you talk this over with somebody who is an expert on the use of trilostane. Here is contact info:

http://www.dechra-us.com/Default.aspx?ID=365

Please let us know what you find out, OK?

Marianne

[goldengirl88]

Letti:
Sorry your troubles continue on, but I agree with Marianne and would suggest you call Dechra too. The number is 866-933-2472. They will keep a file on Simba, which is great. Hope you get things straightened out, and poor Sim gets fixed up. Blessings
Patti

[molly muffin]

Hi Letti, I know you might be upset to read that there is any problems with the current treatment, especially in light of really liking this new vet.

Give Dechra a call and explain it to them and get a case number that you can gie to your vet. Call your vet. Explain what it says on the test results that you have that says her post is in normal range and then discuss the prednisone issue with the vet. That it should be tappered off, that in light of this not be Addisons, should Simba even be getting prednison, as this is a steroid that can cause the same cushing symptoms and raise the cortisol levels that you are trying to maintain in a happy zone. Discuss the thyroid results, etc.

You can do this, you just have to be proactive and see what the vet says. It is possible that the vet hasn't a lot of experience with these drugs and treating cushings but is willing to work with you and learn.

So, lets see where we can go from here okay.

hugs,
Sharlene and Molly Muffin

[Simba's Mom]

I feel like Simba is a test subject, seriously what else can I do wrong, I'm so upset......this vet really seemed to know a lot about cushings...what is wrong, is cushings so new? My head is spinning, what do I do? Ugh

[addy]

Oh Sweetie, I think it is just that so many vets including IMS vets are not up to speed with Trilostane use. I cant tell you how many things our original IMS was wrong about with Trilostane use and even the new IMS said things that I new were incorrect.

I know your head is spinning. Love and hugs being sent your way.

Maybe we just need to adjust Sim's thyroid drug and maybe Sim is a pup who feels better with a bit higher cortisol. Some dogs need to be higher than 4.2. Zoe feels better when she is higher.

hugs

[molly muffin]

It's okay Lettie. You like this vet, lets see if you can work with him to get him up to speed. If a dogs cortisone drops too low and they go into Addisons then sure prednisone is what would be given, or if a macro tumor, then you would careful use both prednisone and trilostane.
However, a lot of vets just read the LOW and the normal range, and don't go into the fine details that are given afterwards and the range is different for a pup treated with Trilostane.
So, call Dechra, tell them what his dosage is, what is results of ACTH are (I printed them here) and that the doctor gave prednisone and you are confused about why and if this is correct. Go from there. Do this first and then after talking to them, either come back here and let us know what Dechra said or call vet and go over it with him.
YOU are Simba's advocate and you can do this. We'll walk you through anything you are confused about. Don't worry.
And when you talk to the vet, mention concerns that the thyroid is high again. Tell him you want to go over these results.
Okay? I know you can do this Letti :)

Super big hugs!
Sharlene and Molly Muffin

[doxiesrock912]

Letti,

I think the biggest problem is that each dog responds uniquely. There is no "one size fits all" treatment plan and that makes things very difficult.

I'm still trying to get Daisy back on track. So far, so good.

You'll get there. Call Dechra and insist that your vet speak with them. Simba depends upon your strength.

[Simba's Mom]

Pity party over, I contacted dechra on the Internet so hopefully they will get back to me soon, tomorrow I will call the vet and find out what's going on, he told me he was going to consult with an IMS in Ames, Ia....Simba is talking half a dose of his thyroid meds, cuz vet did say it was too high....thanks for the encouragement, it just seems like you take one step forward and three steps back, up and down with emotions, this is the hardest journey so thankful I'm not alone, appreciate you all so much.......

[Budsters Mom]

Oh, we love ya Letti:) I am so glad that you went ahead and contacted Dechra. I called them myself when my vet messed up. They were very nice and helpful.:) Give the king a belly rub for me;)
Hugs to you both,
Kathy

[Trixie]

Oh Letti, sorry for what you're going through. I hope it all gets figured out.
It is so upsetting, especially since you had such confidence in the new vet. Hopefully you'll be able to work together with him..and with help from Dechra it will get all sorted out I'm sure!! ;)
Barbara

[goldengirl88]

Letti:
The king deserves the best , so I am glad you contacted Dechra. It will help the other dogs in the future as they keep all this information on file. All the doggies that come after ours will benefit from Simba's information. It is discouraging when you think things are coming together, and they fall apart. Keep forging on Letti, you are Sims best chance at a long life. God Bless You and Sim.
Patti

[Simba's Mom]

Just got back from vet, I called in this morning cuz Simba seemed rounder than usual and they wanted to see him right away...they took X-rays And his spleen is larger, so different vet thought tumor? We have appt Monday for ultrasound and biopsy, so things are not looking so good right now, I'm kinda a mess actually....they sent Simba home with pain pills and keep taking prednisone and no trilo......please pray for my little king of the jungle....

[Trish]

Hi Letti

Oh no, his tummy's not bigger just because he off the Trilo and on Prednisone is it and cush symptoms are rearing up again?? Xray is not a real good test to see what is happening with the spleen. Who is doing the ultrasound on Monday, hopefully it will be an IMS with a high resolution machine. I know my local vet has an ultrasound but it is not a real good one so we have to go IMS to get any scans done so we get the best possible picture.

I cannot remember what your situation is with IMS support? Have you seen one? As I think this would be a good time to go see one.

How is Simba otherwise, any other symptoms besides the rounded tummy??

Feeling for you and sending lots of hugs, I dunno if you know this song "I get knocked down but I get up again, cos I'm never gonna let this get me down" I think of it a lot when I read some of these stories about our struggles with our babies and I am sending lots of hugs to you today and over the weekend too... I am pretty sure you and Simba will get "up again" Letti :) xxxxx

[Budsters Mom]

Hi Letti,
This will just not do for our king!! ;)I had to take Buddy to the emergency hospital for his ultrasound because his vet did not have a high-resolution machine, and he needed a specialist to do the ultra-sound. I don't see how they can see much of the spleen with a regular imaging x-ray machine. An ultrasound is definitely the test that you need. Did his tummy swell up suddenly or has it been getting rounder for some time? If it came on suddenly, it could just be some kind of bloat. The waiting is always the hardest part. We need Mel to commune with universe on Simba's behalf. Until we can get that started, I'm sending tons of love, hugs and plenty of prayers your way. :)
Kathy

[Budsters Mom]

What time is Simbas appointment on Monday, because were all going with you! I hope they have a big waiting room.;):)
Hugs,
Kathy

[Mel-Tia]

Thinking of you both, I have asked Tia to look after him.

I ask princess to look after all the sick and healthy ones often. I also ask my Nan as I think she looks after me..

Big hug to you and kisses to the King.

Mel
Xxxx

[molly muffin]

Hi Letti,

I know you're a mess right now and probably worried to death.
One thing about emailing Dechra, was I got the response that they didn't talk to owners only vets when I emailed. However, it seems that if you call, you get an immediate response and a case number to give to your vet.

Here are the symptoms of an enlarged spleen:

Signs & Symptoms of Enlarged Spleen


An enlarged spleen may lead to such symptoms as:

Diarrhea
Vomiting
Lack of appetite
Abdominal pain
Lethargy and reduced activity
Weakness and even collapse
An appearance of discomfort when attempting activities
Bloating of abdomen

An enlarged spleen is often the symptom of an underlying cause, only one of which might be a tumor. As Trish said you really do need a high resolution ultrasound machine and an IMS to interpret.

Was there any blood cells present in Simba's last urinalysis? A Coagulation profile can help to show how clotting is going. This can be directly related to one of the more common spleen tumors, hemangiosarcoma.

At the moment it sounds like they want to take a look at the spleen for tumors and send a sample of cells to cytology for evaluation. Those are both really good options and should tell you something about what is going on.

I wouldn't worry about cushings at all until this is resolved. This is definitely more important. You know parasites and infections can cause spleen enlargement too.

Hang in there!!! We'll be right with you
Hugs,
Sharlene and Molly Muffin

[Simba's Mom]

I just called Dechra and gave them Simba's info, I feel a little better just talking with someone..Sim has a case number and my vet can call there for dosage info.....today they did check Simba's electrolytes, and they were good......thank you for your encouragement and info, what would I do without you all? How would I find a IMS that is close by to where I live? Could someone help me? Thanks again!

[Harley PoMMom]

To find an IMS in your area, Click on this link: http://www.acvim.org/PetOwners/FindaSpecialist.aspx

Type in your State ONLY! When I searched for Iowa it found 15 matches, so I am hoping one is near you.

[Simba's Mom]

Thank you so much!

[Budsters Mom]

We are here for you Letti and Simba. You are never alone. We so love our King!:)
Big Hugs,
Kathy

[KennyJ]

Terry, just curious. Will vets follow this protocol to make the tests less expensive?




Here is the link regarding reducing costs - http://endocrinevet.blogspot.com/2011/03/how-to-extend-your-supply-of-cortrosyn.html

Terry

[Budsters Mom]

Some will, some won't follow those guidelines to make the ACTH test less-expensive. All you can do is try.;) My vets told me they already do that, but it's almost $300 so I bet they don't.;)
Hugs,
Kathy

[molly muffin]

Letti! I am so proud of you!!! Your vet was consulting with an IMS wasn't he about Simba? See who he has consulted with, what that IMS said and perhaps this might be one that he can refer you to, who is already familiar with Simba's test results. I think you are going in Monday right. So, give the case number that Dechra gave you to your vet also, for consulting, but for now, lets concentrate on that spleen and see what the IMS says.
If you need to find one of your own, you can do that too, but right now you are in a good place for finding one. Do you know if the IMS he is consulting with is in that practice or is at another location?

You're doing great Letti
hugs,
Sharlene and Molly Muffin

[Tina]

Letti, I just wanted to let you know that I am thinking about you and Simba. When he had the xray, did the vet say anything about his liver being enlarged? His tummy could be bigger due to the prednisone he is taking which can cause his liver to enlarge. If this has happened, it will go back down once he is tapered off the prednisone.

This happened to Jasper when he was on a higher than physiologic dose of pred to get his Addison's under control. His tummy got huge and it didn't take very long, I was scared to death. The vet said his liver was enlarged due to the steroid. Just a thought that maybe this could be contributing to Simba's issue also. Hang in there.

Hugs,
Tina and Jasper

[Trish]

Hi Letti

I see you up :) Not sleeping? How is Simba doing?

[Simba's Mom]

Simba is ok, having accidents now in the house, I just feel so bad for him...he is at my feet snoring away so that's good to hear...his tummy is so big, I worry so but taking one day at a time...thanks for checking in, can't sleep either?

[Trish]

It's only 9.30pm here! So bit early for me to be in bed :) Plus I am a night owl :eek: I am scaring myself watching the crime channel haha. Sounds like cush symptoms coming back for Simba, bet you can't wait to see an IMS, hopefully you find one asap. Are any local ones to you open 24hrs, was just thinking you could ring and get appt asap for Monday?? I am hoping it is just tied in with the cush symptoms returning Letti, IMS will get clearer view though with the scan.

[Simba's Mom]

That's so funny I watch the crime channel too, it's called ID here, so I'm an ID addict, sometimes I get so scared, makes me laugh, what a loser :). Simba has an appt Monday with the regular vet who says he has ties with an IMS, so I have a few questions for him that's for sure, thanks for checking in, your Flynny is adorable!

[addy]

Thinking of you and Sim and hoping this is all just from the prednisone. Love and hugs and prayers, Lettie for you and our Simba.

[infoviewer]

Lettie: Hope the IM will find why Simba's belly is so big. Maybe it will go down if he is off the Prednisone. Just thinking of you. Love , JoAnne

[doxiesrock912]

Letti,

I hope that you get answers soon and relief for Sim. Big bellies are not comfortable.

[Simba's Mom]

hey Tina, thinking about it his liver was larger too in xray, so yes I think too it's from the predisone, I hated giving it to him this am, but I can't just stop it either, I never wanted to give him his trilostane so badly, but can't do that either....I did give him some pumpkin with his food, and he did eat it but wasn't too sure of it...the vet did say it would help keep the poo flowing...I was wondering what I all need to ask tomorrow, his appt is at 330, my emotions are taking over my mind so could really use the help, honestly I will just start picking you all up now plz!!!!
Thanks again everyone, each of you help in a different way!

[addy]

Lettie, how is Simba acting while on the prednisone? Is Simba still having leg issues?

Have the vet tell you how prednisone can affect Simba. Ask him how it affects his interal organs as Tina explained.

What symptoms worry you the most?


We are here, sweetie, I know Sharlene will be along to prep you.:)

Holding you tight

[Budsters Mom]

Hi Letti,
I'm just popping in check on you and the king. Much love and great big hugs are headed your way. We need to get Simba fixed up so he can continue his reign. You are not alone in this Letti. We are all right there with you.:)
Kathy

[goldengirl88]

Dear Letti:
I am praying for you and Simba that you are able to get the help you need and get poor Sim back to his usual self. All this with the internal organs is scary, but I am sure you will get it straightened out. Sending some xtra special hugs from me and Tipper. God Bless You and Simba
Patti

[molly muffin]

Hi Letti,

You could ask the vet why he is on prednisone since his ACTH post number was within Dechra recommendations as noted on the lab result and the pre number only a little low.
You could ask whether the prednisone could cause the liver and the spleen to be enlarged and if not the prednisone, then having high cortisol, which we Know enlarges the liver and adrenal glands.
Those would be two of the main questions I'd want to know.
As an example.
Good luck today. Be strong, and ask questions!
hugs,
Sharlene and Molly Muffin

[Budsters Mom]

Letti, what time is Simbas appointment today? Are you going to pick us up or do you want us to meet you there?;) We will be there with you in spirit. We need to make sure that the king gets the best treatment possible! ;)
((((((((((((Hugs))))))))))
Kathy

[Simba's Mom]

Dechra just called me, they are so good......I gave them more info and my vet can call them, they thought maybe the doc is getting Simba ready for the ultrasound biospy, but again they don't know why cuz his pre number was low, a few days off his trilostane wouldv'e taken care of that, and then maybe a lower dose....thanks for your encouragement ladies, you are the best.....the limo should be there soon to pick u gals up and Sim requested all the furbabies too :) the appt is at 330...

[Budsters Mom]

We'll be ready! Buddy wants a window seat! :D
Hugs,
Kathy

[labblab]

Letti, I'm so glad you contacted Dechra and I really think you need to pin your vet down today as to exactly why the prednisone is being prescribed in place of any dose of trilostane whatsoever. I am really hoping your vet will call Dechra to get this question straightened out because it is really, really important.

Marianne

[molly muffin]

Right here with you!!
Remember, a bacterial infection or other reason could be why the spleen is enlarged, so might not be anything dire, but I think the ultrasound is a good idea. :)

scoot over! Molly and me are diving into the car. :)

hugs,
Sharlene and Molly Muffin

[addy]

You forgot me in the parking lot, I had to hitch a ride.

What's happening? Any news?

[infoviewer]

Hope your are back with good news on Simba. I will be watching for your report. Love, JoAnne

[molly muffin]

Next road trip we're going to have to do roll call. Sorry Addy. I could have sworn you and Zoe were over in the other corner. :)

Hoping to hear some good news soon Letti! Simba, rules!

hugs,
Sharlene and Molly Muffin

[Simba's Mom]

Simba is home with me, the vet went ok, he did a ultrasound with a needle biospy.....I will get a phone call tomorrow to find out if its cancer or something else...thanks for all your encouragement....

[Roxee's Dad]

Keeping fingers and all paws here crossed.

[molly muffin]

I vote for something else. :) Whatever it is though, we'll deal with it together. Just like always. :)

Hugs
Sharlene and Molly Muffin

[Budsters Mom]

I am so glad that Simba was able to come home where he belongs.:D I am so proud of you for taking care of all of this and doing such a great job being Simba's mom. Try to get some rest now my dear, you deserve it. Big hugs to both of you,
Kathy

[infoviewer]

Thinking of you and sweet Simba this morning. Hoping and praying it is something that can be treated quickly. We love our babies so much. Keep the faith Lettie, we will all be keeping it with you. Love, JoAnne

[addy]

I said a million prayers last night, hope you dont have to wait all day for the phone call.

Hugs, Lettie

[frijole]

Sending love from here as well. Fingers, toes crossed. Kim

[goldengirl88]

Letti:
Xtra special prayers for you and Simba. You are doing a wonderful job with all of this, and with keeping yourself together. Sim has a great mommy, and Sharlene is right, we are all in this together, we all need each others support. That's what keeps this forum going the kind and caring people who help a friend in need. God Bless you and Sim, we are hoping for the best.
Patti

[Squirt's Mom]

I was distracted and missed the ride too, Addy! But my prayers were with you all and remain with you. Let us know what you learn when you can and know we are all by your side.

Hugs,
Leslie and the gang

[Tina]

All fingers and paws crossed here too. And lots of prayers Letti. I will be thinking about you and your sweet boy today. We are all here with you.

Big hugs from me and Jasper

[Trixie]

Letti,
I'm just catching up on threads. I'm so sorry to hear it's been a worrisome time for you these last few days! I hope you get answers today and that nothing serious is going on.
Looking forward to hearing good news on Simba! :)
Barbara

[molly muffin]

Hey Letti,
Off work and checking in on you and Simba. Hope you heard something positive today. :)

hugs,
sharlene and molly muffin

[Budsters Mom]

Hi Letti,
I'm dropping in to check on you and the king. I hope that you've gotten some good news today. If not, we'll deal with whatever together.:) Sending you and Simba tons of love.:)
Kathy

[Simba's Mom]

Ugh, vet said tomorrow hopefully, this waiting sucks....thanks so much for your encouragement and prayers.....so much for overnighting services....

[molly muffin]

Omg, I saw you had updated and couldn't get my fingers moving fast enough to get over and check!!! arggghhh patience, give us patience. :) (really lacking in that quality)

Hang in there Letti!!
how is Simba doing?

hugs,
Sharlene and Molly Muffin

[Simba's Mom]

Simba is doing ok, I'm gone overnite so his second mommy is watching him, so thankful for her...we went up to Des Moines to see our son and his family, but home tomorrow ;)

[molly muffin]

Enjoy the break! :)
I'm sure Simba is in good hands. :)

hugs,
Sharlene and Molly Muffin

[Budsters Mom]

Okay, That vet had better have really good news or he's fired for making us all wait so long!;):D He doesn't have a clue that he's getting on the wrong side of an army of angels! Not much patience here either!:o We are still with you Letti, for whatever comes your way. Mass hugs and pats for the king,
Kathy

[Budsters Mom]

I am so glad that you took a little break.:D Simba will probably love all the attention his second mom gives him. Enjoy your visit with your son and his family.:)
Hugs,
Kathy

[goldengirl88]

Letti:
I agree this better be good news after the vet making us wait this long. I am praying for great news for the king. Blessings
Patti

[Budsters Mom]

Hi Letti,
What's happening on the news front? I hope you had a good visit with your son and his family. :) How is the king doing today?
Big Hugs,
Kathy

[Simba's Mom]

Simba's spleen is "cancer free", just got call, so plan is to start him back on trilostane and ease off of the predisone, the dose of trilo went down from 25 mg to 18.75 once a day....happy tears today finally!!!!
Thankyou everyone for so much support, me and Sim are going to celebrate!!!!!

[Roxee's Dad]

Woot Woot ... Great news :D:D:D

Sharing in your Happy Tears !!!

[Budsters Mom]

Awesome!!!!!!!!!!!!:D Okay, The doctor can stay. You don't have to fire him!:D
Big hugs all around! Happy tears flowing!
Kathy

[molly muffin]

Yay best news EVER!!!

hugs,
sharlene and molly muffin

[Trixie]

WooHoo!!! :D What great news about Simba! So happy to hear good news!! You must be so relieved Letti!! :p
Barbara

[goldengirl88]

Letti:
Tipper and I are doing the happy dance for Simba. What a relief, we are just ecstatic for you two. Now you can let your mind rest Letti and just concentrate on loving Sim. YAHOOOOOOOOOOOOOOOO!!
Blessings
Patti

[Squirt's Mom]

Oh, Letti, what great news this morning! :):cool::) I am so happy for you both! Onward and upward, Simba!

[addy]

Letti, this is great news. I am so happy to read this:D:D:D

[infoviewer]

That is so great Lettie. Happy day for you today and maybe an extra kiss for Simba. Love, JoAnne

[Simba's Mom]

Hey everyone, thanks so much for all the support through thick and thin, seriously this forum is family to me, you all are getting big hugs from me and wet kisses from Simba!!!
Last nite I gave him his old dose of trilostane, vet says every other day till new meds get here...prednisone too, every other day, hope to get him off that soon.....he seems much happier today, not as sluggish and a little skip to his step...oh wait, do kings skip? Maybe I should think of a better word :) the biggest bother right now is his tummy, it's gurgling away, so I gave him some yogurt, hope it helps....they say that it is as good as Flortaflora? Anyways, we can deal with the tummy stuff, much better day!!!

[Squirt's Mom]

"Swagger", kings swagger. :D

[Simba's Mom]

Awesome, Swagger!!!!!!!

[Budsters Mom]

I am so glad that Simba continues to do well. It won't do if the King is not able to "swagger"out and greet his lowly peasants.;) The balance of the kingdom has been restored.:D
Big hugs,
Kathy

[molly muffin]

Well and who doesn't love a Kingly swagger now and then. hehehe

hugs,
Sharlene and Molly Muffin

[Budsters Mom]

How is the king doing today? I hope you both are having an awesome start to your weekend!:)
Hugs,
Kathy

[Simba's Mom]

Simba is not as good as he was yesterday, today he has pooed every time he went out and he is shaking, I hope the meds can make him feel better and that he's off the prednisone soon....

[Budsters Mom]

Hi Letti,
Poor Simba.:( It sounds like his cortisol level might be dropping too low. Have you let the doctor know what is happening today? He might want you to temporally stop the trilostane. I probably would, until I could get hold of the doctor. Hopefully others will be along shortly to help with this. Big hugs,
Kathy

[Trish]

Ohhh so pleased to read the biopsy was not cancerous, that is such great news and such a relief. Hopefully when you get the meds sorted he will perk up. Why is he still on the Prednisone? Maybe I have missed something here with my speed reading but he is not addisons is he? Is there some other reason he is on the Pred? Sorry for my thickness :) Hope tomorrow is a better day for Simba xxxx

[Budsters Mom]

Hi Letti,
I'm bumping up your thread hoping our experts will have some thoughts for you. I am concerned about Simba's diarrhea and shaking. I'm thinking that his cortisol has dropped too low and you may need to stop the Trilostane temporarily. Others know much more than I do, so I am hoping they pop in shortly. Sending you and the king tons of healing energy.
Kathy

[Simba's Mom]

Thanku gals, Simba is still going poo every time he goes out and his tummy is gurling, just not as bad, poor Sim....He's still on predisone 5 mg every other day and trilostane every other day, a few more day and he can be off predisone vet said and start lower dose of trllostane when it comes in....I have been giving him a tablespoon of plain yogurt twice a day, his shaking is alittle better today, but still not himself.....His little boney spine is odd and then his round belly, I worry so about him....he's drinking more and then not able to hold it, so hes goes out every hour, so glad I'm home today....when will I not worry about him? Just praying for normal days.....

[Trixie]

Oh Letti,
Sorry Sim is having those awful tummy troubles. On top of everything else why, oh why, do we have to have bad poops and tummy issues to deal with too??? :(
It's just not fair. The worrying is awful isn't it? :(
Hoping Simba is feeling better real soon!!
Barbara

[infoviewer]

Lettie: Same here, CoCo will have a firm poop first thing in the morning and the mush the rest of the day. Giving him the Hill's ID, cannot tell it is helping. He is so skinny with his spine showing and his ribs, he may be a little bigger than yesterday, but the day is not over. He does not seem to be getting any nutrients at all. I am wondering if it is the trilostane that is hurting him also. I stopped it a few days, but did not seem to make any difference.Hope Simba will get over it soon. I thought the deworming would help CoCo and he does seem to look better, but still loose stools. I guess it goes along with Cushings. Maybe we will have some good news in a day or two. Always hopeful. Love, JoAnne

[molly muffin]

Good grief. Letti. No wonder Simba is pooing every time and stomach is so upset. Predinson (which he should not have been put on to begin with) is raising the cortisol (it acts just like cortisol) every other day and then every other day you are giving him trilostane which is lowering the cortisol.
You have to wean a dog off prednison, once you start it. So, what I want you to do, is to cut that 5mg pill in half and give him 2.5 every other day for about 4 days, (that would be two doses). Then I want you to give him 2.5 every 2 or 3 days. During the time that you are weaning off prednison, do not give trilostane.

Then I want to take a drive up to your vets office and slap him silly for doing this to
Simba. grrrrrrrr Once Simba is completely off the prednison, you can start back in at the lower dose of Trilostane. You cannot be giving him both every other day, this is wrecking his poor little system.

Maybe Marianne, Lori or Glynda will have a better take on how long to every other day, but we need to get him down from the 5mg, to lower doses at less frequent times.

Hang in there. We'll get this worked out.
hugs,
Sharlene

[Simba's Mom]

Thank you for your kind words everyone, and the info too Sharlene...I actually cut his prednisone in half yesterday, I just knew he shouldn't do both, ugh, why can't my new vet know what's he's doing, I feel so bad for putting Simba through this all....he said he talked to an IMS in Ames, IA, so I feel like I can trust I'm but then he puts Sim on prednisone and I start to wonder after learning what I do on this site what's right? Could someone tell me how long the trilo stays n the system? Thanks again

[Roxee's Dad]

Oh Letti, I am so sorry for what you are both going through. Trilostane works in the system about 12 hours, could be as long as 18 hours... could be a few hours less. That is why every other day dosing is so confusing and doesn't make much sense. Seems like Simba is on a high... low cortisol roller coaster.

For the hours after dosing with the Trilo, does Simba's cushings symptoms subside? Symptoms like appetite and thirst?

[Simba's Mom]

Yes John, he seems better after the trilo is given....

[labblab]

Letti, I am also beyond frustrated with your vet for putting Simba on the prednisone in the first place. And now the every other day dosing of pred and trilostane sounds totally crazy. In answer to your question, in most dogs, trilostane exits the body in 12-18 hours.

Because Simba is doing so poorly right now, I really think you need some expert guidance as to exactly how to proceed with the prednisone taper and how many days you should be dosing at each level. I don't think you can make this decision on your own. Of course, complicating everything is the addition of the trilo on alternate days, as well. That just sounds crazy and like a roller-coaster for poor Simba's system.

Letti, you have already contacted Dechra once and they have a file all made up re: Simba. I strongly encourage you to call them back first thing on Monday and tell them what your vet is asking you to do. Then, I'll bet they will ask you to have your vet call them, just like they did before. Does your vet flat-out refuse to call them, or are you perhaps feeling awkward asking him to do so? I do understand that it may feel uncomfortable pressing him to talk to them. But I think Simba is at the point where he really, really needs to have some expert guidance re: this whole prednisone/trilostane mess. Either your vet needs to talk to Dechra, or you need to request a direct consultation with the IMS at Iowa State yourself. Because the way your vet is handling this is crazy and cannot be doing Simba any good. :(

Marianne

[Simba's Mom]

The last time I has Sim at the vet, I questioned my new vet about the prednisone and how dogs with cushings make their own, he didn't really seem to hear me and at that place they were all worried about Addison's ..I also asked him to check his level when I was there but he said it wouldn't matter....seriously why don't these vets know, thanks Marianne I will call dechra...

[Roxee's Dad]

I very strongly agree with Marianne and Sharlene. Please do call Dechra and if nothing else, please have someone explain "why" the every other day dosing.

Simba's cortisol is under control for 12 hours or thereabouts. Then it returns to a higher level for about 12 hours, then it zooms up even higher after the pred dosing.

[molly muffin]

Can you call your vet and ask how long they expect this weaning off of prednisone to take? I'm unsure of how long you need to do the every other day dosing at 2.5 mg.
Also call Dechra and tell them what you are currently giving Simba and see what they say.
I really want him off the pred but I'd like to see it done safely and in the best manner possible.

This seems to be a real theme on here lately, but have you tried SEB with Simba's tummy? you give it with a bit of food, but not within 2 hours of medicine. You get some powder and make a brew of it by boiling it in water.

http://www.holvet.net/slippery_soup.html

Sharlene and Molly muffin

[Simba's Mom]

I just called Dechra and they are going to give me callback on Monday, my vet still thinks Sim is on 5mg every other day, I cut it in half yesterday.....he didn't have anything today just his thyroid med...thanks everyone for your help, my vet isn't available on weekends so I have to call an all city pet care and talk or see another vet if emergency......

[labblab]

Letti, does this mean you cut Simba back all on your own to 2 1/2 mg. when you first switched to the every other day dosing a couple of days ago? If so, I am worried that you are cutting back on his prednisone too abruptly. Even though I don't understand why your vet started him on the prednisone on the first place, I think you need to abide by your vet's instruction to begin the taper by first dosing with 5 mg. every other day. If Simba was taking 5 mg. daily for ten days, I do not think you can comfortably drop down to 2 1/2 mg. every other day right off the bat. This may be part of the reason why Simba is feeling poorly right now -- his adrenals have not had the chance to rebound cortisol production on their own, and they are additionally getting dosed with trilo on the "off" days. So I think you need to stick with the 5 mg. every other day until you can talk to Dechra on Monday. Again, I must stress I am not an expert on prednisone. But I think you need to follow your vet's instructions about the prednisone taper at least for the weekend.

Marianne

[molly muffin]

Oh I thought you had been giving him the every other day of 5mg already. If not then I agree with Marianne, continue every other day of 5mg and then eventually you will taper to 2.5. This just all has to be so gradual as prednisone basically takes over the function of the adrenal glands. Good if you are in an Addisons situation, not so good if you aren't.

I am concerned about giving the trilostane though, when what we want to have happen is the adrenal glands to start working on their own producing the cortisol instead of needing the booster of the pred. This is why it is important to speak with Dechra and your vet should be talking to to them too. That is very important, especially as he doesn't seem to be that experienced with the drug.

hugs,
Sharlene

[Budsters Mom]

Thanks angels for coming to Letti's and Simba's rescue. :)I bumped up their thread this morning hoping it would draw attention, because I knew that I was over my head! You're the best and the brightest!
Kathy

[Simba's Mom]

On June 16, Simba was started on prednisone 5mg, yesterday I gave him 2.5 for the first time, so now do I give him 5 mg tomorrow and stop the trilostane?