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View Full Version : 9 1/2 years old pug...cushing causing stroke



kat
08-16-2012, 11:41 AM
I noticed that my pug was more tired, she was resistant to go up and down the stairs. I spoke to the vet about it on our regular checkup & I was told that this was normal aging & the fact that she is overweight (the stairs). On May 28, my pug was sitting on the floor & just felt on her back-she was unable to walk, was pannicking and it seems both her rear legs were not functionnal anymore, she looked crazy & devastated. We rushed her to the vet hospital right away. The process cost a fortune-they knew she had neurological problems but could nottell if it was a stroke or a cerebral tumor-I paid for the extremly expensive IRM because I did not want her to suffer so much if it was a brain tumor-for strokes, they suggest to wait three weeks to see if the dog will improve. She had lost response of her pupil in both eyes, her back legs were non responsive, her head was tilted on the side & she was unable to drink or eat on her own-we were able to give her soft food bringing it directly to her mouth...The IRM indicated a hemmorrage in the cerrebellum, no tumor. After three weeks, she got better but she stayed hospitalized the first week because she was not urinating. They found a tumor on her adrenal gland & mentionned the possibility of cushing disease. Howerver, all the possible tests for cushing are in a grey zone-they cannot confirm the diagnosis 100% but the vet stated that given all the clinical signs (she drinks a lot, eat a lot & has a big stomach-but pugs always eat a lot & tend to be overweight), she should start treatment for cushing. She started with vetoryl, 30mg per day. She is also taking aspirin to avoid blood thikening. Ten days later, we did the test: based cortisol was 30 (N:15-120nmol/L) and the post ACTH : 273 (N:220-550nmol/L)-(I am french speaking & my vet as well, not sure if the terms are the same). She is since taking 40mg of vetoryl per day, it will be a month now that she is on this dosage & she will be going for another test next week. She will also go for an abdomen echo to see if the tumor on her adrenal gland changed size & they mentionned possible surgery. I am not sure what I will do at that point-seems that surgery will be less costly on the long run but after all she has been through, I am very reluctant to make her go through a surgery and anasthesia... She will be 10 years old in october. Now she walks, eats & drink by herself (still a lot, I do not see much change with the vetoryl honestly), her back legs will remain weak & she will never be able to go up and down stairs again, but at least, she seems OK and was able to get back a good quality of life. They say the cushing caused the stroke, I wish I knew about this disease before & we could have prevented the stroke...

Good luck to you all.

molly muffin
08-16-2012, 10:18 PM
Hello and welcome. I'm so glad you found our forum. Some of the others will be by that are more familiar with the lab results.
I'm glad to hear that she is doing so much better after the stroke. How horrible to think that cushings could have been the cause. That is very scary. Hopefully though the vetoryl will keep her in a good range and nothing like that will ever happen again.
Again welcome to the forum. We're all one big family here, going through the same thing.
Hugs,
Sharlene

lulusmom
08-16-2012, 11:20 PM
Hi and welcome to the forum.

Can you please round up copies of all testing that was done by your vet to diagnose adrenal based cushing's. I am not sure what tests were in the grey zone means but if your dog doesn't have elevated cortisol, she should not be on Vetoryl (Trilostane). Adrenal tumors have random patterns of secretion and it is not uncommon for a dog with an adrenal tumor to have an overproduction of sex hormones with normal cortisol. I spoke with an internal medicine specialist on staff with Dechra, the manufacturer of Vetoryl and he said under no circumstances should a dog with normal cortisol be given Vetoryl. I'm also wondering why your vet felt the need to treat with so few problematic symptoms. It will help us a lot if you post those test results.

Glynda

P.S. It is extremely rare that a dog with cushing's has a stroke. We've seen hundreds of case studies here and I can't recall a dog who had a stroke attributed to cushing's.

frijole
08-16-2012, 11:25 PM
Welcome from me as well... I too have never seen a case of cushings cause a stroke and I've been here over 7 years. Please let us know all tests that were done and results if you can get them. It will help us help you. Glad you found us. Kim