Corkster - adrenal tumor/3x daily trilostane (Corky has been released)

[littleone1]

Thank you so much Carrol.

Corky really liked the big hug and belly rub.

I really appreciate you thinking about Corkster.

[addy]

Hi Terri,

Thinking of you and Corkey and hope things continue to do well on the new dosing schedule.

I am glad to hear our little Trail Blazer is feeling better and sleeping through the night:) I sure wish I could take a pill at 4:30 am and go back to sleep:D:D:D I would just stay up:rolleyes::rolleyes:

Hang in there dear friend. I hope you are finding some fun things to do to help with the stress.

Many hugs and kisses to you and Corkey.

Addy

[littleone1]

Hi Addy,

Thank you for thinking about us. Our little Trail Blazer is doing pretty good.

I also wish that I could go back to sleep after I give Corky his dosage. I find myself waking up around 3 to make sure I'm up to give him his Trilo. :( He's really been good about taking his meds. His automatic alarm clock lets him know when it's time for them. :D

Corky and I are sending lots of love, hugs, and kisses to you. Give Zoe lots of belly rubs from me and kisses from Corky. I hope you will soon get answers to your questions about giving Zoe Lyso.

[apollo6]

It is so good to hear some good new. Corky is a trooper.
Hugs Sonja and Apollo

[littleone1]

Corky finished his first week on the 3x daily dosing with Trilo. He did have a few issues one night, but I didn't give him his Pepcid AC that day. Since then, he has been doing well with this dosing.

This is definitely a new experience for Corky and me.

[apollo6]

Makes me smile to hear good news about the Corkster
Hugs Sonja and Apollo

[Franklin'sMum]

Yay!!! :D Great news Terri! I am so glad the 3x dosing is working really well for you and Corky, and hope it continues to bring improvement. :D

Love and hugs,
Jane, Franklin and Angel Bailey xxx

[Bichonluver3]

Hi Terri!
So glad everything is going well. We face a great trial tomorrow when I will have my first go at taking Sparky's (my diabetic pup) first blood glucose with home testing:eek:. Sparky & I chatted this evening and he told me that if I was serious about doing this crazy testing, he was packing his bags and leaving home!
Keep the fingers, toes & paws at your house crossed for us tomorrow!
Carrol

[littleone1]

Thank you Sonja, Jane, and Carrol.

Corky and I are both keeping everything crossed that everything goes well with Sparky's testing. I hope he didn't pack his bags.:) If our furbabies could talk, we might not want to hear what they have to say!:D

[addy]

Great news Terri:D Keep it coming:):):)

Dear Friend, are you okay? I have been worried about you but I tend to be overprotective with those that mean a lot to me:rolleyes:

Love,
Addy

[Bichonluver3]

Hi Terri!
No, Sparky didn't leave home 'cause......his dad caught him at the door!!!!
The testing went great but the results are not so good. Posted info on K9diabetes.
Thanks for your good wishes. You're a sweetheart.
How are you and how is our Corkster?
Love,
Carrol

[littleone1]

Thank you for caring Addy, my very dear friend. I'm fine. I'm just a little under the weather. I thought my allergies were acting up, but I was wrong. I have a nasty cold. :( I haven't had a cold in years. This was so sweet of you to ask.

[littleone1]

I'm glad Sparky didn't leave home. I'm glad the testing went well, but I'm sorry the test results weren't good.

Our Corkster is doing good, but I have a nasty cold.

You are also very sweet Carrol.

[Bichonluver3]

Just checkin' in on Corks........
How's the cold?

[littleone1]

Thanks for checking on us Carrol.

Corky's doing good. He has been sleeping all night, and his water intake is back to normal. He's still looking for food, but not as much as he was before the increase in his dosage.

My cold is a little better. I'm getting there slowly, but surely.

Take care.

[addy]

Chicken soup!!!!!! You need chicken soup:D

Glad to hear our little boy is better and hope you are better soon.

Hugs and belly rubs,

Addy

[Bichonluver3]

Yaaaaay, Corkster!!! You know, Terri, Addy is right - chicken soup (maybe with a little schnapps??;))
Miss Chloe has been looking for a snack lately - usually in the middle of the night. Maybe I could send her to your house to keep the Corkster company. They could hunt for food together:D
Love, Carrol

[littleone1]

Thanks Addy and Carrol. I hope Corky continues to well with this dosing.

Great minds think alike. :D I have been eating chicken soup. Corky likes it, too. :)

You can Miss Chloe anytime. Corkster would love it!:D

[maish costello]

Remission.......is this possible?

[littleone1]

Hi Maish,

Corky was originally diagnosed with cushings over two years ago. He had all of the clinical signs, and we were ready to start his treatment. I even had the meds. He had developed two UTI's, and was on two ABs. We couldn't start his treatment until he was off of the ABs for at least 14 days. His clinical signs disappeared and were in remission for 7 months. When they started to resurface, he was tested again, and he did have to be treated this time. There are other members on the forum who also had cushpups whose clinical signs were in remission for several months.

Terri

[apollo6]

Dear Terry was in the middle of posting lost info.
Think you called. Will try to call back. Major harddrive crash over weekend. Had to have harddrive replaced. Won't get back until Friday. So I can't do my work , order Apollo medications. Everything is on my main computer. Glad Corky is doing better. MAY take a few days to get on line again. Won't have back until FRiday. Trying to work on laptop. Apollo just falls down all the time now. Made appointment with regular vet to restart Trilostane and pray that it will help with all of this.
Hugs Sonja and Apollo.

[littleone1]

Hi my friend.

I did call. Give me a call if you get a chance.

I'm so sorry that you and Apollo are going through all of this. My PC crashed on me twice, but the company I used actually came to my house. They had a disc that they used to to get into my hard drive and were able to restore my files. I now transfer my files to a flashdrive.

Corky is doing better, but he is still looking for more food. I might have to give him the higher dosage. I'll wait until he has his stim test.

[Bichonluver3]

Just checking in to see how everything is on the homefront:)
Hugs,

[littleone1]

Thanks for checking. I think Corky's dosage is going to have to be increased, but I'll wait until I get the results from his stim test, which is in 2 weeks.

He's here waiting for Sparky. :D

[Bichonluver3]

Ha ha! Corky might have to wait a few days for the visit - Sparky's butt is to sore to move!!

[mypuppy]

Terri,
Don't have too much time, trying to get Ariana on the bus, but was curious why his stim results are going to take 2 weeks? Wow. Sorry he may need an increase again. Does this mean you will go back to BID dosing and just increase or are you going to continue the 3xs per day? Sorry for all the questions. I love ya both. Xo

[littleone1]

Hi my dear friend.

I'm waiting 2 weeks, as Corky just had a stim done 2 weeks ago. Some of the clinical signs had improved, but I'm seeing some of the issues returning. When he has the test, the 2 or 3 times daily dosing will be left up to his IMS to decide. I went with only an 11mg a day increase, and maybe I should have gone with the 20mg a day increase.

Talk to you soon.

Luv ya bunches. (((HUGS)))

Terri and Corkster

[addy]

Hi Terri,

Just checking in as I was thinking Corlster had a stim this week but in rereading your last post I see it is later in the week.

So I will wish you lucky early:) Hope things are gong well for the cutie pie.

We were admiring the Boston Terrier shown at Westminster and I kept thinking of Corkster. Not that I am prejudice or anything but he is cuter:D They sure are a wonderful breed. It was funny, they would should a dog and I would immediately think of someone here on the forum. I also especially liked the Lhasa, she was such a pretty color. Again, not that I am prejudiced towards Lhasas:rolleyes::rolleyes:

Hope you have a wonderful day!!!!

Hugs and love,
Addy

[mypuppy]

Addy,
Sorry to chime in here.... I think we all love all breeds, but are definitely partial to our own or certain others for some special reason--(I LOVE LABS, ummm, I wonder why?)--LOL., But I must agree with you that the Corkster is one cute little fellow. What can I say, he's my nephew, and your little girl is not too shabby herself..haaaaaa...

Lots of tight hugs for both of you. xo Jeanette and Princess THE LAB...lol...

[addy]

You sure have an adorable nephew, Jeanette:D and thanks for the compliment for Zoe:)

Whenever I watch a dog show, I want one of each, LOL, I have a fondness for labs too.:D One of the pups at work is part lab and part rotty. She is smart as a whip and easy to train. If someone asked me to list my top ten favorite breeds, I could not do it;););) Now I am going to check out your lab!!!!!!!!!:)

Hey Terri, we all love the Corkster cause he is just so dang cute:D:D:D

Of course, we also have a fondness for Mom too!!!!!!!!!!!!

As you can see, I am home from work today:cool:

Love ya,
Addy

[littleone1]

Thank you my very much my very dear friends, and thank you Addy for the good wishes with Corky's stim. He's having it done on the 28th, which will be 12 years to the day that Jay and I got him.

I think your furbabies are also so cute and adoreable. I have to admit that I am a little partial to my Corkster. :D I tell him everyday that he's the cutest little boy in the whole world.

Jeanette does have a wonderful nephew, and Princess is a terrific niece. Addy, you are now Corkster's aunt, and Zoe is my niece.

Love both of you bunches. (((HUGS))) for you and belly rubs for your precious babies.

[mypuppy]

Addy,

you are so right. if I could take them all I would--they are all just so irresistible! gosh these creatures are just too darn cute all around. BTW, thanks for your picture comment of my 3 beautiful girls--that was taken on my Princess's 8th birthday so it is even extra special. My human daughters (14 and 6) just love their 4 legged sister to pieces, as it should be, and there is no sibling rivalry there--lol. I took a peek at your pics as well, and well as I said earlier, that Zoe is a little ham.. I could eat her right up. Lol. very precious. At any rate, Terri, sorry for taking up your thread--lol, but one last thing to add to Addy's comment about Corky's mom--she is a keeper---haaaaa. Love you Terri, Corky, Addyand Zoe. Xo Jeanette

[apollo6]

Just a quick hello. Will be praying about Corkey's stim test.
I think he is a cutie also. Not motivated with everything going on. Will try to call you this week. I have piles of paperwork everywhere.
Hugs Sonja and Apollo

[addy]

Jeanette does have a wonderful nephew, and Princess is a terrific niece. Addy, you are now Corkster's aunt, and Zoe is my niece.

I take that as an honor, my friend.:D

Love ya,

Addy

[littleone1]

Hi my dear friends,

Thank you for all of the compliments. You are all very special to Corky and me.

I'm looking forward to hearing from you, Sonja.

(((HUGS))) to all of you. Love ya bunches.

Terri and Corkster

[addy]

Hi Terri,

Checking to make sure Corkey's stim went okay. I will be crossing fingers and toes, arms, legs, paws, whatever I can:D hoping results come back in a good range.

Thinking of you both,

Love,
Addy

[littleone1]

Thank you so much Addy. I should get the results today.

[Bichonluver3]

Hi Terri!
Just checking in on you and the Corskster. Am anxiously awaiting your results, also.
Have not been posting as I have still not been "myself". I am going to make an appointment with the doctor as I am on thyroid medication and maybe my thyroid level has taken a nosedive:(.
I will check in periodically today to see if the stim results are in.
Love.
Carrol

[apollo6]

Praying for good news.
Hugs Sonja and Apollo
P.s. Glad I called. Enjoyed talking to you.

[littleone1]

Hi Carrol and Sonja,

Thank you for checking on us and for the prayers for good news. I didn't get the test results today. I normally get them the next day, especially since the tests were done early yesterday morning. I'll post the results as soon as I get them.

I hope you're feeling better soon Carrol. I'm glad you're going to see your doctor.

I also enjoyed talking to you Sonja. I'm so happy that you called.

Take care my friends.

[Bichonluver3]

Okey dokey. Will check back tomorrow. Have a good night, my friend.
Love & hugs,
Carrol

[littleone1]

Thank you my friend. You have a good night, too. I am calling it a night.

[littleone1]

Hi everyone,

The verdict is in. Corky will be staying on the TID, but his dosage is being increased to 60mg a day. His Pre stim was 3.2 and his Post was 9.2. Last time his Pre was 2.5 and the Post was 10.7.

Except for his BUN, BUN/Creatinine Ratio, and his platelet count which are still slightly elevated, all of the rest of his blood work was in the reference range. His Triglycerides went from 860 last time down to 159, with a ref. range of 29-291.

[lulusmom]

Hi Terry,

All in all, the results of the bloodwork seem to be pretty darn good, especially the huge drop in triglycerides. That's awesome!!! I'm sorry the stim test results were not better but I have no doubt that you'll get Corky where he needs to be.

It's interesting because we've had some recent discussions about using basal cortisol levels to monitor Vetoryl treatment but Corky's results raises some doubts for me. His basal cortisol on the last two stim tests were perfect but as far as I'm concerned, the post cortisol draws were uncomfortably out of range. Have all of Corky's symptoms resolved?

G.

[littleone1]

Hi Glynda,

All of Corky's symptoms have not been completely resolved. If they were, his IMS was going to keep him on the 51mg TID, but since they're not quite resolved, she increased his dosage.

Corky's blood test results have usually been very good, which I'm thankful for. I think his Triglycerides were really high the last time because his cortisol level was as high as it was.

If we used the baseline cortisol level with Corky on most of his previous stims, they were low, and that would have led to him being taken off of the Trilo, which would have been a disaster.

[Bichonluver3]

Way to go, Corkster. Congratulations on the drop in triglycerides! Your mom may want to attribute it to elevated cortisol last time but you and I know it was all your hard work :D You have such an amazing mom that I am sure your numbers will all be where you want them with her help.
How is your weather?? It is beautiful - sunny and warm in the California desert. Even Miss Chloe will venture out until it gets too hot and then the little princess demands A/C:rolleyes:
How is the Corks acting/feeling? You mentioned he still has some symptoms.....
So glad you can now feel at least some relief. You deserve it.
Love,
Carrol

[Harley PoMMom]

That is a significant drop in those triglycerides!!! Awesome!! What a great job you are doing, Terri!!!!

I am in total agreement with Glynda in that you will get our Corky where he needs to be!

Love and big hugs,
Lori

[littleone1]

Hi Carrol,

Corkster is a little fighter when it comes to his health. He always has been. He doesn't let anything get him down. Thank you for your very kind words. I try.

Corky still has some issues with his water intake, his hind legs, but he's getting better about not wanting my food. The issues are not extreme, but they're not where they should be. We're getting there.

The weather is beautiful here. We probably were close to 80 degrees. Corky loves the warm weather. He loves to lay in the sun. He also needs the AC on when it gets too hot.

Enjoy your evening.

[littleone1]

Thank you so much Lori. You always make me feel like I'm doing a great job.

I'm hoping we can get our Corky's cortisol level where it should be and keep it at an even keel. It's been just about 17 months since he started taking the Trilo. His level keeps going up and down with the dosage increases.

Thank you again for everything.

(((HUGS)))

[addy]

You do an amazing job, Terri, you always do with Corkey.

A little more tinkering and you will probabaly be there with his dosage.

Now to relax and enjoy your evening with your little boy.

Have a wonderful night!!!

Love,
Addy

[littleone1]

Thank you Addy. I hope we get there soon.

He's right next to me, cuddling and snuggling.:D

I hope you also have a wonderful night. :)

[frijole]

Good update! I agree that all in all it is positive and what more can we ask for right?! :D Terri keep up the great work and hug the little monster for me. Kim

[littleone1]

Thank you Kim. I'm really pleased with Corky's blood test results, especially after being on TID with the Trilo.There's been no problems with this dosing. I just gave the little monster a hug from you. :D He looked at me and went back to sleep.:D He is so much calmer.

[John II]

Terri,

Such good news about The Corkster! Well done!
Please give him a cuddle for me. :D

[gpgscott]

Glad to hear that the increase in dosing is moving numbers in the right direction Terri. Corky really does put a point on the fact that treatment can be very different pup to pup.

I am sure the slow go is tough on you.

Hugs to you both. Scott

[mypuppy]

Hello dear friend,
That is amazing with the lower triglycerides--how great for the Cork and you and us.:). Wish his cortisol would have been stabilized, but unfortunately as we have been learning, these dose adjustments seem to do the trick for them. Hoping we can talk soon but in the meantime, lots of love and hugs. ILU and Corky much. Jeanette

[labblab]

It's interesting because we've had some recent discussions about using basal cortisol levels to monitor Vetoryl treatment but Corky's results raises some doubts for me. His basal cortisol on the last two stim tests were perfect but as far as I'm concerned, the post cortisol draws were uncomfortably out of range. Have all of Corky's symptoms resolved?




All of Corky's symptoms have not been completely resolved. If they were, his IMS was going to keep him on the 51mg TID, but since they're not quite resolved, she increased his dosage.

If we used the baseline cortisol level with Corky on most of his previous stims, they were low, and that would have led to him being taken off of the Trilo, which would have been a disaster.
Terri, congratulations on the positive bloodwork results!!!! And like everybody else, I'll surely be keeping my fingers crossed for you and Corky as far as this trilo dosing change.

I apologize in advance for hijacking your thread for a moment here, but I just wanted to add a couple of additional thoughts about using baseline cortisol for monitoring purposes. First off, my understanding is that the notion is still very much in the experimental phase with much more research and substantiation needed before it could be a widely acceptable approach. But so as not to throw out the baby with the bathwater, here's how Corky's results might have been viewed using the baseline approach...

According to a recent article by Dr. Audrey Cook (who is the lead researcher in the area), baseline cortisols between 1.3 and 2.9 (or less than 50% of the pretreatment baseline) may represent a "comfort zone" in which it may be possible to assume that cortisol is being adequately controlled as long as a dog is clinically doing well with all symptoms resolved. But if symptoms remain, I believe an ACTH is recommended, regardless of the baseline result. And even if a dog is clinically doing well, if baseline cortisols fall outside of this range, I believe the recommendation is still to follow-up with a stim test to make sure that the dog is not being over-suppressed (post-ACTH less than 1.5) or under-suppressed (post-ACTH over 9.1).

So in Corky's case, I'm guessing that follow-up ACTH's would have been recommended for him, even using the baseline approach. On the face of it, his most recent baseline cortisol was too high and fell outside of the acceptable monitoring range. And his symptoms had not all resolved at the time of the previous testing. And if his earlier baselines were too low for the range, again, I'm assuming that the recommendation would have been to proceed with a stim test rather than just discontinuing his trilostane. I'm really curious, though, to start keeping better track of all our members' ACTH testing. I'm curious to see whether this baseline range between 1.3 and 2.9 (coupled with symptom resolution) really does regularly pan out in conjunction with acceptable post-ACTH results.

Here's a recent "write-up" regarding the research: http://veterinarymedicine.dvm360.com/vetmed/Medicine/A-simpler-way-to-monitor-adrenal-function-in-patie/ArticleStandard/Article/detail/698185

Marianne

[littleone1]

Thank you John, Scott, and Jeanette.

It hasn't been an easy journey, but Corky keeps hanging in there and is a real trooper.

I am very pleased with the results of his blood work.

Jeanette, my very dear friend, we will talk soon. Corky and I also love you.

[littleone1]

Hi Marianne,

Thank you, and thank you for your input. If we went by Corky's baseline level, it really would have presented a problem. The last two baselines were in the reference range, but his posts were high. Going back within the last year, his baselines were between 0.9 and 1.3, consistently. I am definitely going to keep having the full ACTH stim test done. Even when Corky's symptoms were under control, his baselines were still very low. I would rather be safe than sorry.

[lulusmom]

I'm curious to see whether this baseline range between 1.3 and 2.9 (coupled with symptom resolution) really does regularly pan out in conjunction with acceptable post-ACTH results.

Me too and that's why I asked Terry about symptoms.

[labblab]

Yes, we can create our own little research sample, here at k9cushings! ;)

And I'm afraid my original reply ended up being pretty long-winded. I was mainly just wanting to point out that Dr. Cook's baseline cortisol reference range is not the same as Dechra's post-ACTH range. It is much more restricted, and so only one of Corky's cited baselines would have been considered "OK," and even then, only so if his symptoms were resolved at the time (which they were not).

In the real world, even if accurate, I'm guessing that a baseline cortisol monitoring scheme will have pluses-and-minuses. In some instances, it has the potential to save money and time -- which could be a big benefit. But in other situations where the baseline result is out-of-range, the dog would end up having to return to the vet for a second visit in order to be stimmed. So that's an added expense and pain as opposed to having performed the stim in the first place.

Maybe it will turn out that there are different monitoring phases when baseline cortisol will be of greater or lesser value. For instance, if the reference range does turn out to accurately weed out oversuppression, then maybe it could be performed (along with an electrolyte test) at that initial 10-14 day checkpoint (at the start of treatment or after a dosing change) when the biggest concern is mainly making sure that the cortisol hasn't dropped too low. Then a full ACTH could be performed at the 30-day mark for a complete evaluation of the treatment effect. Just total mind-wandering, here...

Marianne

[littleone1]

I wish we could use the baseline results to monitor the cortisol levels. The cost of Corky's last stim went up well over $50. His IMS said that the cost of the Cortrosyn really went up and so did the lab fees.

I really wish that there could be cut and dry answers and results, but I know that will never happen. :(

Terri

[lulusmom]

Terri, how much does Corkey weigh? Do you know if your IMS is giving you a break on the cortrosyn by using only 5mcg/kg and storing the rest of the vial for future stims? I know for certain that it keeps for up to six months if stored and frozen properly but I've also heard that it's good for up to a year. Depending on how much Corkey weighs, I think you could get two to three stims from one 250mcg vial. It is definitely worth discussing this with your IMS. I'm sure he probably knows how to properly store the cortrosyn but if not, he can email Dr. Mark Peterson and he will provide instructions. I have been remiss in not passing on this tip to members with smaller dogs because it can save them hundreds of dollars.

[littleone1]

Hi Glynda,

Corky weighs 19 pounds. I know his IMS uses the right amount per weight. She told me quite awhile ago how much she uses. I have it written down, but I would have to go back through Corky's records. I was paying $250 for well over a year, but now it's over $300.

When I looked for info regarding specialists experienced in using Trilo, Corky's IMS is just about the only one in AZ. I know she's not overcharging me. She's been really good about her costs. Most of the time, she doesn't charge me anything for Corky's U/Ss.

[Buffaloe]

Hi Terri,

I know the costs for repeated ACTH tests are difficult. My surgeon's facility charges well over $300 for the ACTH now.

Another member was asking me about Internists in the Phoenix area. My girlfriend took her diabetic cat to your IMS about a year ago and I went along for the ride. Anyway, I looked at your Internist's website. The woman is incredibly smart. She received her bachelor's at MIT. Then, did her vet training at The Ohio State University. Then, she got her masters in microbiology and molecular genetics at Harvard, followed by her three year residency at Wisconsin. Give me a break, educated at both MIT and Harvard.

It is wonderful that she gives you such a huge break on ultrasounds. All the best to you and the Corkster.

Ken

[littleone1]

Hi Ken, and thank you.

I remember when your girlfriend took her cat to Corky's IMS. I know she is very knowledgeable and knows what she is doing. I have complete faith and confidence in her. She has really been good for Corky and me. She's always works with Corky's vet and me. She takes the time to go over everything with me. She never minds me bringing my list of questions and concerns.

I hope all is well with you.

[lulusmom]

Hi Terri,

Your IMS should get five stims out of one vial of cortrosyn for a 20 pound dog. If you are paying over $300 for a stim, the cost of everything must have gone up substantially. How can cortrosyn possibly get any more expensive? It's as ridiculous as the price of gas these days. :D

I found a local gp vet who gives me a rescue discount. I pay $195 for Lulu and Jojo is only $100 for a total of $295. I paid that for one at my IMS. The last one was done two months ago so I'll be curious to see if that changes when i take them back at the end of the month.

[apollo6]

Dear Terry
Better latter than not at all. You have good news with not so good news. Stim tests can be very high. I have paid $101.33 to $138.88 for the test and $40.50 for the Cortrosyn.
Will be cheering for the Corkster.:p
HUgs Sonja and Apollo

[littleone1]

Hi Glynda,

It's not only the cost of the Cortrosyn that went up, but the lab fees also went up. I just got Corky's Trilo today, and that also went up. Price increases are never ending. I hope you still get good pricing.

[littleone1]

Hi Sonja,

Not to worry. I know you have a lot on your plate right now.

[Cushpup]

I wish we could use the baseline results to monitor the cortisol levels. The cost of Corky's last stim went up well over $50. His IMS said that the cost of the Cortrosyn really went up and so did the lab fees.

I really wish that there could be cut and dry answers and results, but I know that will never happen. :(

Terri

For whatever it's worth, the IMS I had gone to a couple of weeks ago said that he uses baselines as a guide (resting Cortisol), but only after an ACTH test is done a couple of times previously. His experience is that a dog being on Trilo with a resting Cortisol of less than 3.5 (between 1-3.5) will be normal post.....meaning he'll be between 1-5. The blood drawing has to be done 3-6 hours post dosing just as if you would do the entire ACTH.
I asked him about that specifically and he was very confident about it.

I don't know if the same answer would apply for a dog being pilled
3x daily, though.

[littleone1]

I appreciate your input, but I'm afraid I disagree with the theory. Corky has had many stim tests done in the last 17 months, and until the last two stims, his baseline levels were low. If we would have gone by the baselines, it really would have caused problems for Corky. Corky started out on once daily dosing of 20mg of Trilo. He then went to BID, and now TID dosing. In Corky's case it might be because of his adrenal tumor. His stims are done between 4-6 hours after his dosage.

I just want to add that the 1-5 is for a furbaby being treated with Lyso. One that is being treated with Trilo, the range is 1.5-5.5

Terri

[AlisonandMia]

My feeling with this use of baseline testing (along with observation of symptoms) is that it is something that will work really well for some dogs and maybe not so well for others.

A lot of these protocols are devised with PDH in mind and ADH can be very different. There seems to be even more variation between how each case of ADH behaves than there is between each case of PDH (and there is a lot of difference there too.) From what I've seen here, each ADH dog seems to really write their own book!

Alison

[littleone1]

Thank you Alison. I believe that Corky is writing his own book. He is a very unique little boy. :)

Terri

[mypuppy]

hey there my friend,
I just want to agree with you on the increases of price statement. It is pretty sad because I feel with the rise of these vet bills it may steer people away (specially those on a fixed incomes or other financial circumstances) from treating their pup according to the protocol. I for one, must admit the vet bills have added up at 260.00 a pop for Princess's stims, then there's the meds ( I thought I would see a huge savings in lowering her dose, but I can't believe it is only a 10.00 difference per month). then there's food, grooming and other regular vet bills. But since I love this pooch to pieces, that good old credit card is being used a lot--I pay the minimum balance and that's all I can do, and I will continue to do everything possible for my baby. hope you and the Cork are well. Tight hugs. Jeanette

[apollo6]

Dear Terri
Just see how you and the Corkster are doing. Like everyone else the costs keep going up and in such a bad economy it is a hard pill to swallow. But like most of us I will do what I can for my Apollo.
Hugs Sonja and Apollo

[littleone1]

Hi my friends,

I know we're all facing the rising costs, not only those for our furbabies, but for everything else. We definitely do everything we can for them.

Thank you for checking on Corky, Sonja. He is adjusting well to the increase in dosage. He gave me a slight scare Sat. morning. He always eats when he gets back from his walk, but that morning he wasn't eating. I gave him a treat after 2 hours, and he ate that. Then I put something special on top of his food and he finally ate. He was just being finicky. He tried the same thing yesterday and today, but I didn't give in. He decided he'd better eat, as he wasn't getting anything else.:D He's sleeping all night once again, and he is much calmer. So far, so good.:)

[addy]

Oh, I bet that was indeed a scare for you. I am so glad Corkey decided to stop being finicky.

I always say the day Zoe throws up or does not want to eat turkey, I better run as fast as I can to the emergency room with her.

I hope Corkey continues to do well, dear friend.

Love ya,
Addy

[littleone1]

Hi everyone,

I'm sorry I haven't been posting on threads for awhile. I'm worried about Corky. He's been exhibiting some different behaviors. When I'm doing something in the kitchen, instead of watching me, he starts roaming through the house aimlessly. He started pawing at a few things, which he never did before. When I get the mail in the afternoon, he always goes with me to sniff in the yard, and then I take him for a ride. Recently, he just sniffs a little, and instead of going to the car, he goes to the door to the house. Yesterday, when I was getting our dinner ready, he was on the pool deck, with his head over the edge, looking at the water. :( He's eating, drinking, and sleeping good. He still goes for his long morning walks at a very fast pace. I don't know what to make of all of this. Has anyone else experienced this?

I have been thinking about all of you, hoping that all of your furbabies are doing well.

[labblab]

Terri, did these changes seem to begin at the same time that you shifted to dosing three times daily? I'm wondering whether Corky's cortisol level may be staying too "flat" throughout the day, so as to alter his attention level somehow. Just grasping at straws, but I thought I'd at least throw it out there. Maybe with your vet's approval, you might want to just temporarily revert to twice daily dosing again as an experiment in order to see whether that results in any improvement in his behavior.

Marianne

[littleone1]

Thanks Marianne.

He was doing good with the 51mg TID. Even though his cortisol level was higher than it should be and his dosage was increased, the 60mg might be a little too high for him. I'll be calling his IMS this morning.

[Squirt's Mom]

Hi Terri,

Just popping in to say you and Corky are on my mind, hoping things are looking much better for him today.

Keep being a great mom - like you could be anything less! :p

Huge hugs,
Leslie and the gang

[littleone1]

Thank you Leslie. You are so kind.

Corky doesn't seem as anxious today. I called his IMS yesterday, but she wasn't in. I left a message for her. They are keeping an opening for Corky, in case she wants me to bring him in. I'm also either going to call or e-mail Dr. Allen on Monday, to find out if any of these behaviors are related to TID.

(((HUGS))) to you and your babies.

[Harley PoMMom]

Hi Terri,

I sure do hope either Dr Allen or Corky's IMS will have some answers for you. Give sweet Corky some kisses and hugs from the me and my gang...BIG CYBER HUGS to his MOM!!! :)

Love ya both,
Lori

[Bichonluver3]

Hi Terri!
Just took a few moments to check in and see how everyone is doing and was sorry to hear the Corkster is having difficulties. I am sure that between the 2 docs, they will get everything sorted out.
Hugs,hugs, and more hugs,
Love ya'
Carrol

[littleone1]

Hi Lori,

I hope I can get some answers. The roller coaster ride continues. It's never ending, but we manage to get through it.

Thank you for the big cyber hugs. Corky loved his hugs and kisses from his aunt and cousins.

We love you, too my dear friend. (((HUGS))) back at all of you and belly rubs for my nephews.

Luv ya,

Terri and Corky

[littleone1]

Hi Carrol,

Thanks for checking in on us. I have a feeling that Corky's IMS and Dr. Allen will be talking with each other again. Corkster' s IMS never used TID before, and hopefully Dr. Allen will have some answers.

Thank you for all of the hugs my friend. I'm sending them back to you, and give lots of belly rubs to your precious furbabies.

[apollo6]

Dear Terry so sorry to hear about Corky.
Yes it is a roller coaster ride. It may be the effect of the higher dosage. It seems to make them more leathargic, not as energetic.
Will be praying for you and Corky.
Hugs Sonja and Apollo

[littleone1]

Thank you Sonja for your prayers.

Corky isn't really lethargic. He's just the opposite. I just need to wait to talk to his IMS and Dr. Allen to see if they have any answers as to what is going on with Corky.

I was a bad girl yesterday. I gave Corky pizza for dinner. He loves pizza and hasn't had it for a long time. He really enjoyed it. I figured he needed something special.

Take care my friend. I'm sending positive thoughts for you and Apollo.

[addy]

I think if our little trooper likes pizza, go for it:D:D:D:D Zoe would love a pizza party:D I gave her a bully stick Friday while I was cleaning. I figured, what the heck, she has the metronidazole and she LOVED IT:p:p Her poops were a bit wet and sticky one time, nothing bad. Sometimes we have to spoil them, they deserve it:)

Hoping you get some answers to put your mind at ease, dear friend.

Sending prayers and positive thoughts,

Love,
Addy

[littleone1]

Hi Addy,

Thank you my dear friend for the positive thoughts and prayers.

I agree with you that we should spoil them. Our Corkster enjoyed the pizza so much. It doesn't hurt to give them something special once in awhile. I'm glad Zoe enjoyed the bully stick. I still don't know what they are.

Take care my friend. Give Zoe lots of belly rubs from me.

[marie adams]

Hi Terri,

I hope you get wonderful answers for what ails the Corkster!! :):) A little spoiling makes everyone happy!!!

Take care!!

[littleone1]

Thank you Marie.

Corkster definitely gets spoiled. :D:D:D He deserves it.

You also take care.

[littleone1]

I just spoke to Dr. Allen. He feels that Corky's behaviorial changes are not related to his medication or cushings, unless Corky has developed a pituitary tumor, which he thinks is unlikely. He said there's a possibility that there might be something going on neurologically, since Corky has lost most of his hearing and his eye sight is getting worse. Dr. H. does wants to see him today. I have a 2 o'clock appointment.

Terri

[labblab]

Terri, good luck at your appointment today. I am really hoping that you'll be able to find an explanation that is easy to address.

Big hugs to Corky,
Marianne

[addy]

sendings healing thoughts for my sweet little nephew.

Love,
Addy

[littleone1]

Thank you Marianne and Addy.

I hope I can get some answers today. Corky loved his big hugs, Marianne. He thanks you Aunt Addy for your healing thoughts.

[littleone1]

We just got home. Corky's behavioral changes are due to Canine Cognitive Dysfunction and his adrenal tumor. The tumor is right next to the inferior vena cava. There's no space between the two of them. Dr H. had me look at the U/S results as she was doing it. She recommended giving Corky Sam-e or Anipryl to help his cognitive functions. We're going to try the SAM-e first. It had to ordered, as the kind she had is not the one to give Corky.

Terri

[mypuppy]

Hi Terri,
Do not know much on this, but glad you were able to figure this out and that medication will help him with his behavior lately. Awww poor Corky, but as with everything else he will continie to be strong for this new challenge. God Bless and I keep you both very close to my heart and in my prayers. Tight ones. Xo Jeanette and Princess

[Squirt's Mom]

Hi Terri,

I'm glad you got an answer and plan in place. The SAMe would be my first choice, too, tho Squirt didn't really have any problems with Anipryl.

Here are some links on CCS/CCD:

CCS info

http://www.thepetcenter.com/imtop/cds.html
http://www.cpvh.com/Articles/4.html
http://www.lbah.com/cds.htm *
http://www.cdsindogs.com
http://www.veterinarypartner.com/Content.plx?P=A&A=2549


Keep your chin up, sweetie!
Hugs,
Leslie and the gang

[apollo6]

Dear Terry
So sorry to hear about Corky. You are doing all you can for the little guy. On the lighter side, Apollo gets whip cream and applesauce on the weekend. With all they are dealing with a treat now and then is well deserved.
Hugs Sonja and Apollo

[littleone1]

Thank you Jeanette, Leslie, and Sonja.

Jeanette, thank you for keeping our Corkster and me in your prayers and for the tight hugs. Down deep inside, even though I know Corky has gotten through so much, I really don't know how much more he can go through. Looking at the U/S of the adrenal tumor really has me scared. He still has the mass on his liver.

Leslie, thank you for the links. Now I have more research and reading to do. Can I pull my hair out now? :D

Sonja, I agree that they should have something special to eat with everything they've been through. I'm at the point now where I'm going to give Corky something special more often. He really deserves it.

(((HUGS))) to all of you.

[apollo6]

Dear Terry
I know what you mean. Your little angel has been through so much already. All we can do is hope, pray and appreciate the time we have left with our precious angels. Each day become a gift with them now.
It is a hard pill to swallow.
Hugs Sonja and Apollo

[littleone1]

This is so true Sonja. (((HUGS))) for you and Apollo.

[Casey's Mom]

Terri I am sending you big (((hugs))) and give Corky some more pizza from Casey. You really don't know what a bully stick is? It is kind of disgusting but the dogs love them :))

Love and hugs,

[littleone1]

Thank you for the big hugs Ellen. I will definitely give Corky more pizza, as he really loves it. Corky thanks Casey. :D I really don't know what a bully stick is. The next time I go to Pet Smart, I'll check it out.

[John II]

Dear Terri,

So sorry to hear Corky is experiencing this new problem.
I'm hoping the doctors are on top of it and Corky will bounce back!
Bear hugs to you.
Ear & chest scritchies for Mr Corkster.

[littleone1]

Thank you for the bear hugs, John. Corkster thanks you so much for the ear and chest scritchies. I'm hoping the SAM-e will help him.

[sunimist]

Terri, I have been following all the latest with you and Corky both here and on FB and just want you to know my thoughts and prayers are always with you.

Love ya...Shelba

[lulusmom]

Hi Terry,

Bully sticks are 100% bull penises. I hear dogs love them but I can't see myself watching my dogs chompin on one. :D

http://www.bullysticks4dogs.com/bully_sticks_made.htm

[littleone1]

Thank you for your thoughts and prayers, Shelba. They are really appreciated.

[littleone1]

Oh Yuck! Thank you for the information Glynda. I now know that I would never get one for Corky.

[sunimist]

Double YUCK!! Couldn't stand seeing Suni with one of those yucky things in her mouth! I'm afraid her kisses would be limited too! :eek:
I sure didn't know that's what they are made of. Thanks much Glynda!

[Roxee's Dad]

Terry,

So sorry to hear the Corkster is having an additional problem, but I am sure he knows how much he is loved and enjoys all the special little meals you give him. Big Hugs from me and mine and a special little belly rub for The one and only "Corkster"

[addy]

Double YUCK!! Couldn't stand seeing Suni with one of those yucky things in her mouth! I'm afraid her kisses would be limited too!
I sure didn't know that's what they are made of. Thanks much Glynda!

Okay guys, she eats raw turkey and raw turkey organs, a dried up penis can't be that bad:rolleyes::rolleyes::p

SHHHHH, just don't tell hubby:eek::eek:

Addy

[mypuppy]

Haaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa!




Hi Terry,

Bully sticks are 100% bull penises. I hear dogs love them but I can't see myself watching my dogs chompin on one. :D

http://www.bullysticks4dogs.com/bully_sticks_made.htm

[StarDeb55]

Not to continue this threadjack, but I am always looking for some type of chew treat for both boys, especially Obi. I have read Addy's posts about how much her pups like the bullysticks, so I ordered some yesterday. I read all of this earlier today, & basically, went:

DOUBLE YUCK!!!!!!!

Oh well, they will get this order, but I may not order any more of them.

Debbie

PS- Sorry for the hijack, Terry.

[littleone1]

Thank you for your kind words and hugs, John. Corkster is indeed loved very, very, much. The one and only Corkster thanks you for the special little belly rub. In my opinion, he is one of a kind. :D

[littleone1]

I don't mind thread hijacking, but this topic is making me sick!

[addy]

awww, Terri, I'm sorry. That is why I never told you what they were.

Don't want you to be sick:o

Let's think of something nice, like Susan is almost to her destination to pick up her puppy. Did you read her thread?

Hugs and kisses and lots of sorrys

Addy

[frijole]

:eek: WOW... this wasn't the update I was expecting but it was good for a giggle... dried bull penises.. what next? For crying out loud....

[littleone1]

Not to worry Addy. I don't give Corky anything that isn't fully cooked. I know there are many people that feed their furbabies a raw diet, but it's just not for Corky and me. You don't need to be sorry my friend. I just didn't realize what they were.

I haven't read Susan's thread. I'll have to check it out. Marlene is also getting a new furbaby. She's the cutest little baby! :)

[littleone1]

I know Kim. You never know what they'll come up with next.

[Squirt's Mom]

Oh my dear.....Crys LOVED those things and she couldn't destroy them in a few minutes so she got to have them. Oh dear... I have picked up slimy pieces of bully stick that she hid all over the house I can't tell you how many time. Oh dear....I had NO idea what I was picking up! :eek::eek:

I know those things are very difficult to cut/break. The 3' pieces were cheaper than buying several of the smaller pieces so that is what I got, thinking we would just break it into pieces for the girls. They DO NOT break, cut with steak knives, carving knife (electric) hack saws, or hand saws. Jim ended up putting in on his table saw!

No wonder good breeding bulls are so prized! :D:p:eek::o:D:p:eek::o

Hugs,
Leslie and the gang - who will never touch a slimy bully stick again!

[mypuppy]

Sorry for the squeamish folks here, I hear y'all, but this topic is definitely entertaining. What will they think of next Terri, Im sure they will have bulls balls dog treats to match their other anatomy---haaaaaaa. I mean I know humans eat those. As for Princess I think she will stick to the chicken breast and venison backstrap. LOL.

Xo J.

[Squirt's Mom]

Im sure they will have bulls balls dog treats to match their other anatomy---

Uh oh...this reminded me of a story. :D

MANY years ago, I was a governess for 3 little ones. We lived in a swamp in southern ARK on a little 5 acre island. Part of my duties was to cook for the folks who worked and lived on the place.

One day, the owner/father told me there were some mountain oysters in the freezer if I were so inclined. So I pulled them out, thawed them, breaded and battered them, fried them, and served them with potatoes and corn on the cob. I was so proud of myself since cooking was relatively new to me.

I was also incredibly naive and gullible.

When they all came in and sat down to eat, MJ (owner/father) looked at the platter of mountain oysters and burst out laughing. I was so hurt! He was laughing at my hard work. :( When he told the rest of them what was on the platter, they started guffawing too.

Mountain oysters are bulls balls and they were for fish bait! :eek::eek: MJ had been joking with me when he told me they were in the freezer, thinking I knew what they were! :D:p:D:p

[littleone1]

I'm sorry, but can we please change the subject. Thanks.

[Bichonluver3]

OMG, Terri, I am so sorry I have been caught up with Sparky's problems and have neglected my friends.
I was sorry to hear the Corkster is having problems of his own :(
You know that all my love, hugs and prayers go out to you always.
I will be checking in.
Hugs, hugs and more hugs,
Carrol

[littleone1]

Not to worry, Carrol. Your main concern right now my friend is Sparky. I've been doing the same thing because I've been so worried about Corky.

I'm returning your love, hugs, and prayers. They are greatly appreciated. I hope Sparky will be okay and continue to improve.

(((((HUGS))))) for you and your furbabies.

Luv ya,

Terri and Corkster

[addy]

Okay guys, no more anatomy talk here, we are getting poor Terri upset:(

I promise, Terri, to never mention chews again!!!!!!!!!!

How is our Corky today? You have so much on your plate again dear friend. I know how worried you are.

Glad to hear about Marlene's puppy. That is good news.

Hoping you and Corkster have a good day together. I guess we all just have to make every day count some how.

Love,
Addy

[apollo6]

Dear Terry just checking in.
Hope you and your Corky are doing a little better.
Hugs Sonja and Apollo
Give the little guy a hug and kiss from me.

[littleone1]

Hi Addy and Sonja,

Corky is still the same. He's still eating, sleeping and drinking, good. He's still wandering around aimlessly. I should get the SAM-e tomorrow. I hope it helps him.

Thank you Addy for promising not to mention chews again. It's never ending my dear friend.

Thanks for checking on us, Sonja. I will definitely give Corky a hug and kiss from you.

[labblab]

Terri, I am so sorry that Corky's wandering is continuing. That sort of thing is so hard to watch. I am sending you many hugs.

And of course, there is always a special hug for Corky. I have my fingers crossed that the SAM-e will help. I am guessing it may take some time, though, before it may make a difference? (Unfortunately, patience is not one of my greatest virtues...:o)

Marianne

[littleone1]

Corky and I thank you for the hugs, Marianne.

It is hard to see Corky this way. At least if I sit on the couch, he will lay down next to me. I'm also hoping that the SAM-e works. I hope Corky will show some improvement in a short period of time.

[Bichonluver3]

Dear Terri,
I am so sad to hear Corky is under the weather. I am praying for him with all my might, my friend. Keep us updated. I hope to hear good news soon.
Tight hugs, I love ya' lots,
Carrol

[lulusmom]

Hi Terri,

I don't often post to your thread but I have been keeping close track and never miss your updates. I am so sorry that you are having to deal with the heartbreak of watching the Corkster struggle with dementia. I wish you could just wiggle your nose and figure out of the SAMe is going to work but I don't think you'll really know for a good month or two. I had never heard of using SAMe to treat doggie dementia so I did some research and found a great paper entitled "S-adenosylmethionine (SAMe) and canine dysfunction in dogs. A roundtable discussion". It's a great reference paper and in case you haven't seen it yet, I've included a link below.

So it looks like our Corky is creating history by being the first to be on TID Vetoryl dosing and now the SAMe for CD. I am keeping fingers crossed that both will prove to be positive for Corky. No matter what, I'm here for you if you need anything or just want to talk.

www.virbacvet.com/Libraries/PDFs/Novifit-roundtable-discussion.sflb.ashx

Hugs,
Glynda

[littleone1]

Carrol, thank you my friend for your prayers and tight hugs.

Luv ya bunches. (((HUGS))) for you.

Terri, and of course Corkster

[littleone1]

Hi Glynda,

Thank you so much. Thank you for the link. I hadn't read this one. I've been trying to keep my mind occupied by being on FB.

It is heartbreaking to see Corky this way. Bless his heart. I wish he could get a break for a change.

I would rather have my Corky be healthy instead of making history. Hopefully, everything will help him.

I will give you a call this weekend. Thanks again Glynda.

[littleone1]

Corky started his new meds this morning. He's actually sleeping. He's taking 100mg of Novifit S once daily for a period of 1 to 2 months. If his condition doesn't improve, or if it gets worse, I'm suppose to stop giving it to him and call Dr. H. I'm keeping everything crossed that it does help him.

Terri

[addy]

Oh Terri, I am hoping the medicine helps our little trooper.

Thinking of you and Corkster and sending love.

Addy

[Squirt's Mom]

Hi Terri,

I am so glad to hear that Corky is resting. He is probably worn out from all the pacing he has been doing. :( Poor little guy.

I looked up the Norifit S 'cause I wasn't familiar with it and found this:


NOVIFIT S is a highly pure and stable form of SAMe (NoviSAMe) presented in an enteric-coated tablet.

I hope it does the trick for him and that you start to see more of your old boy soon!

Hugs and belly rubs,
Leslie and the gang

[mypuppy]

Dearest Big sis,

I too will be keeping fingers crossed but mostly keeping my prayers going for our little boy. You are both real troopers. we love you.
Xo Jeanette and Princess

[apollo6]

Dear Terry
It breaks my heart to hear about Corky. I am praying for you. Wish you get some good news for once.
Hugs Sonja and Apollo

[littleone1]

Dearest Addy, Leslie, Lil Sis, and Sonja,

I hope the meds do help our little trooper, Addy.

Corky probably is worn out, Leslie. He sniffed around more when I got the mail, but he still didn't want to go for his ride. The Novifit is the one Dr. H. wants him to take. That's why she had to order it.

Thank you for keeping your fingers crossed and for your prayers, Lil Sis. Corky and I also love you and Princess.

Thank you for your prayers, Sonja. I hope I will have some good news to post after he's been on the meds for awhile.

(((HUGS))) for all of you and belly rubs for all of your precious furbabies.

Corky and I luv ya.

Terri

[Franklin'sMum]

Dear Terri,

I am so hoping that Corky has improvement with the Novifit, and that it helps him get back to being Corky.
Much love and many hugs,

Jane, Franklin and Angel Bailey xxx

[littleone1]

Thank you, Jane. It would be so nice to have my Corky back.

I'm sending lots of love amd hugs back to you and Franklin.

Terri

[Casey's Mom]

Terri I am so sorry to hear of Corky's new issues. Hopefully the meds will help him. A few years ago Casey would pace and pace and pace all night instead of going to sleep and I put her on melatonin at nightime and it helped. She doesn't do that anymore and I don't give it to her so I am sure its not the same issue but at the time when I asked the vet about giving her melatonin she said that it also helps with doggie dementia. Just a thought.

Casey doesn't do that anymore but she is so spoiled - she paces and goes out and comes in from about 8 oclock at night on until I go upstairs to bed with her. - she won't go alone.

Hugs to you and Corkster.

[Bichonluver3]

Oh, Terri,
I am so sorry you are having these problems. I don't like to see the Corkster under the weather. I pray that the new medication will have him feeling better soon. After this past week, I personally know the toll that this worry can take. But, you just have to hang in there as you well know. Stay strong, my friend, we are all right beside you and our Corky.
All my love and hugs to you, tummy rubs to Corky,
Carrol

[littleone1]

Thank you Ellen. I do have Melatonin that I give Corky when we have bad storms. I would have to check with his IMS to see if I can give him both of them, but I hate the thought of giving him any more meds right now, because he's also taking his allergy pills.

Corky had his second dose of SAM-e this morning. There has been some improvement. When my friend was here this morning, Corky wandered a little, and then he came in the house and layed on the couch. His wandering seemed purposeful and not aimless this morning. My friend even commented about the difference in Corky since last Sunday. So far, so good.

Thank you for the hugs.

[apollo6]

always good to hear something good. Did you consider this happening with the new dosage?
Hugs Sonja and Apollo

[Squirt's Mom]

Wonderful! So glad your friend came to visit and commented on Corky's improvement!

[littleone1]

Thank you Carrol. I'm hanging in there. Worry definitely does take its toll on us.

I posted back to Ellen a little while ago. There has been some improvement in our Corkster.

Thank you my friend for the love, hugs and prayers. Corky loved his tummy rubs.

Luv ya. (((HUGS)))

Terri and Corkster

[littleone1]

Hi Sonja and Leslie,

It is so nice to have some good news.

Sonja, I did wonder if this had anything to do with Corky's increased dosage. Both Dr. Allen and Dr. H. ruled that out. It's just one of those things. It happens to some people when they get older, and it also happens to some furbabies.

[addy]

Good news is the best.:)

I hope Corkster continues to improve dear Terri.

Worry causes us stress and then we get sick from the stress.:(


If we could only turn back time and make them all well. Sorry you have had such a time. I'm glad you had a friend visit and have positive remarks. That is always good to hear.

Keeping everything crossed for both of you.

Love,
Addy

[lulusmom]

Awesome news. We'll be keeping fingers and paws crossed that the improvements continue.

Hugs,
G.

[littleone1]

Thank you Addy and Glynda. I'm hoping to see a little improvement every day. Even if it is just a little better, it means alot.

I also wish that I could turn back the hands of time to a time when Corky didn't have all of his medical issues.

[AlisonandMia]

You mention that Corky is on allergy meds. Is that some sort of antihistamine? I ask because some antihistamines can affect behavior.

Alison

[littleone1]

It is Alison, but Corky didn't need to take them for quite awhile. It's been about 2 years since he had to take them. It's just within the past week that he's really been congested and sneezing. The behavioral changes surfaced before Corky started taking his allergy meds again. He had a total of 3 pills last week. He only gets them when he's congested. He's was taking them before, but he never had any issues with them.

Terri

[littleone1]

Corky has continued to show improvement since he started taking the SAM-e. He has not been wandering the last two days, and he even wanted to go for his ride today. He's still eating and drinking his normal amounts, and he's been sleeping more during the day. He's definitely not as restless as he was. He's back to watching me when I'm getting meals ready, instead of roaming around.

Even though his Trilo dosage was increased, since there are no signs that his Cortisol level is getting too low, he won't be getting another stim test done for another 30 days.

Terri and Corkster

[apollo6]

Dear Terry
so glad to hear the Corkster is doing better.
Hugs Sonja and Apollo

[Casey's Mom]

Great news Terri!!

Love and hugs,

[mypuppy]

Awwwwwwwwwwwwwwww, such great news first thing in the morning. So happy Corky is showing signs of his old self. Tight hugs and rubs. Xo Jeanette and your niece Princess

[Harley PoMMom]

Corky has continued to show improvement since he started taking the SAM-e.

This is wonderful, wonderful news!!! Sending big, big hugs and kisses to you both!

Love and more hugs,
Lori

[addy]

THE BEST NEWS EVER!!!!!!!!:D:D:D:D

Love,
Addy

[labblab]

YAY!!!!!!!!!!!!!!!!!!!! :) :) :) :) :) :) :) :)

Marianne

[Squirt's Mom]

Yippee!!!!!

Great news, Terri! :D

[littleone1]

Corky and I thank all of you for your prayers, love, hugs, and kisses. Thank you for being here as I share my positive news. I'm hoping the roller coaster will stop for awhile. :D

Extra hugs for all of you.

[Dollydog]

Hi you two....I'm so glad to hear that Corky is feeling more himself....what a relief!
Jo-Ann :)

[John II]

Excellent news! :D

[apollo6]

Dear Terry
It warms my heart to hear good new for our Corkster. It gives me hope for Apollo.
HUgs Sonja and Apollo

[littleone1]

Thank you John, Jo-Ann and Sonja. There's always hope.

The roller coaster ride is still going. :( Corky started having respiratory problems again Friday night. He's sleeping now, and hasn't eaten anything today. It could be due to the high temps and winds that we've been having. I'm going to let him sleep and not try to feed him right now. I'll see how he acts when gets up.

[addy]

Oh, Terri, I know how scary those respiratory problems can be from just last week with Koko.:eek:

Hopefully it is allergens and he will feel better soon. It took Koko a week to stop sneezing from swallowing or breathing in water:(

Big Hugs and MANY kisses, tummy tickles to Corkster.

Love,
Addy

[apollo6]

Dear Terry
So sorry to hear about the set back. Apollo gets very winded now , labored breathing if he walks a little. He is becoming more intolerate of heat. I am think of getting a cool it bandana for his neck to keep him cool.
Always on my prayers
Hugs Sonja and Apollo

[Dollydog]

Hi Terri.....how is he now? Did he eat?

[Squirt's Mom]

I just saw your post, Terri. How is Corky feeling today? Sending many prayers and hugs, healing white light and love to you both.

Let us hear from you when you can!
Hugs,
Leslie and the gang

[littleone1]

Hi Addy, Sonja, Jo-Ann, and Leslie,

Thank you for your concern and all of the hugs and love. I know I was very worried about Corky, since he was hospitalized in April and May two years ago with respiratory distress.

Corky's doing much better today. He finally ate yesterday afterrnoon. He was really hungry. He slept most of the day. I even had to cancel his play-date. I didn't give him most of his meds yesterday, but I did give him his allergy pills, which really helped. He's been getting very congested recently. His IMS even commented on it when Corky was there the last time.

This morning he went for a long walk, and as soon as we got home, he couldn't wait to eat.

(((HUGS))) for all of you.

[addy]

Oh Terri, I am so glad Corky is feeling better. Zoe too has been sounding "nasally" but it is off and on. Nasal conjestion may be a better term. I was starting to wonder if she had a sinus infection.

Hopefully it is all the allergens this time of year. We have had so much rain it is a wonder we have not floated away:D

I hope you can get off the roller coaster and on to the Merry Go Round:D:D

Love,
Addy

[Harley PoMMom]

I have just now seen your post about Corky's respiratory problem! So glad he is feeling so much better, sending huge, loving hugs to you both.

Love and more hugs,
Lori

[Squirt's Mom]

Glad to hear that Corky is feeling better today, Terri! :D

[littleone1]

Thank you Addy, Lori, and Leslie.

Corky has been doing so much better today. He's still a little congested, but he still has an allergy pill to take. With it being so dry and windy here, we've had high pollution advisories. I'm glad it was just his allergies and nothing else. :)

Corky and I are sending you huge hugs and lots of love. Give your furbabies lots of belly rubs from me and kisses from Corkster.

A Merry-go-Round sounds good to me Addy. :D

[Casey's Mom]

I am so glad to see that Corky is feeling better - I think the scariest thing is when they won't eat so I feel for you. Belly rubs to Corky from me and Casey.

Love and hugs,

[littleone1]

Thank you. Ellen. Corky thanks you and Casey for the belly rubs.

It is a worry when they won't eat.

Corky ate good yesterday and had a good night. His congestion was cleared-up. I have to keep him on his allergy meds for a few more days.

[apollo6]

Dear Terry
So glad to hear our little Corkster is doing better. :o
Hugs Sonja and Apollo

[addy]

Stopping in to check up on you and Corkster.

I am hoping he is still doing well and things are good at your house, Terri.:)

Hoping Corkster has a weekend filled with happy times and belly rubs along with some special treats.

And I am hoping your weekend is filled with Sonja's Special Sunday Drinks!!!! They are soooooo good:D:D

Love,
Addy

[littleone1]

Hi Addy,

Thanks for checking on Corkster and me. Corky is still doing good on the SAM-e, but he hasn't wanted to go for his afternoon rides recently. Several times during the week, he would only eat half of his morning meal, but he ate all of his dinner. He goes back for his stim and blood work a week from this coming Monday. I'm going to see if his IMS wants to take x-rays of his hind legs, especially the right one. He's been acting like it's hurting him, as he hardly puts any pressure on it. It could be a problem with the pin. He still takes off trying to run when he goes for his walks in the morning, but he's been hopping really fast.

I hope you have a great weekend my dear friend. Give Zoe and Koko lots of belly rubs from me.

[apollo6]

Dear Terry
Just checking in on you. Hope Corky gets better. I am having same problem with Apollo with the legs.
Hang in there
Sonja and Apollo

[littleone1]

Hi Sonja,

Thank you for checking on us. I'm just about positive that Corky's hind leg problem is due to the pins in his hind legs.

I hope the therapy is helping Apollo.

[marie adams]

Hi Terri,

Sounds like you have things under control with the Corkster!! It is a never ending job of watching every little thing...:o

I hope you are doing well yourself!!:):)

Have a most wonderful day!!!:D ((HUG))

[littleone1]

Hi Marie,

Thank you. I'm trying to keep things under control. You are so right. It's never ending. We do the best we can do for our furbabies.

I'm doing good. I hope all is well with you.

I hope you're having a wonderful day.

[Franklin'sMum]

Hey Terri,

Just popping in to send you and Corky love and hugs.

Jane, Franklin and Angel Bailey xxx

[littleone1]

Hi Jane,

Corky and I thank you for the love and hugs my friend. We're sending them right back to you and Franklin.

Terri and Corkster

[Bichonluver3]

Hi Terri!
Been away from the forum for a bit. Just read about Corky's respiratory scare. Am so relieved that he is feeling better. Tell Corky I only want to hear good things about him from now and give him a BIG tummy rub from us.
Love & hugs,
Carrol & Chloe

[littleone1]

Hi Carrol,

I'm glad you're back with us. I gave Corky your message. Hopefully he listens.:D He loved his big tummy rub.

[apollo6]

Dear Terry
I am glad Corky is doing better. The roller coaster ride never ends.
Hugs Sonja and Apollo
A big hug for the Corkster.

[addy]

Oh Terri,

I am glad our Corky is doing better. What a relief. We have to have some good news somewhere:)

I hope you are having sunny, relaxing days.

All our love,

Addy, Zoe and Koko

[littleone1]

Corky's day of terror is over for at least 30 days, hopefully 3 months.

There was nothing unusual that showed on the x-rays of his hind legs. Dr. H. is having a surgeon look at the x-rays on Wed. to see if she sees anything, since Dr. H. is not a surgeon, and might have missed something with Corky's hind leg pins. Once Corky's test results are back, a decision will be made as to whether or not to keep him on the SAM-e or to keep him off of it for 30 days.

[Harley PoMMom]

So happy to hear that nothing showed up in the X-rays.

If the Same-e is helping than why does your IMS want to stop it...just curious!

Sending huge and loving hugs to you and sweet Corky. :)

[addy]

T
Go Corky!!!!

That is good news but I am curious like Lori, why would he have to go off the SamE?

Love ya,
Addy

[littleone1]

Hi Lori and Addy,

The SAM-e that Corky is taking has directions on the package from the company that says to take it for 1-2 months. Since he's already taken it for one month, his IMS wants to see the results of his blood work before deciding if he should continue taking it, or if we should wait a month before he takes it again.

We love you both.

[Squirt's Mom]

Hi Teri,

I am so relieved to hear the results of Corky's Xrays on his legs. That was good news! :D Hopefully, he is experiencing nothing more than arthritis.

Hugs,
Leslie and the gang

[apollo6]

Just checking in on you.
Glad the xrays don't show anything. Any postive is helpful right now.
Hugs Sonja and Apollo

[littleone1]

Hi everyone,

I got the results from Corky's blood tests. His pre stim was 1.2, and his post was 4.0. :D His cortisol level is back in the normal range again. He will be staying on 60mg of Trilo, TID, and he doesn't have to go back for his next stim test for 3 months. All of his other blood test results, except for his BUN, which was still slightly elevated, are in the normal range.

He will be off of the SAM-e for at least 30 days, to see if this helps with his bowel movements, which did change after he was taking it for awhile, and he lost a pound in 1 month, as he wasn't eating as much in the morning, and he let his food sit for at least an hour before he would eat it. He might even be off of the SAM-e longer if he doesn't revert back to where he was before he started taking it.

The surgeon looked at his x-rays. The pins are where they should be. His knees, legs and hips looked good. It's his arthritis acting up.

I really feel relieved with all of Corky's results.

[apollo6]

Dear Terry
I am so happy for you:p:D Corky , you go little boy.
Hugs Sonja and Apollo

[littleone1]

Corky thanks you, Sonja. He's still like the Energizer Bunny. :D

[MBK]

Terri -

That is GREAT news! So happy to hear of someone having good results!! Go Corky!

I am really leaning towards starting my Alivia on Trilostane. Is the dosage usually 3 times a day? I'm not sure how I would manage this with my work schedule.

Mary Beth and Alivia

[littleone1]

Thank you Mary Beth.

Trilostane is usually given once a day with food. Corky started with once daily dosing, and then was switched to twice daily dosing, as some of his symptoms weren't being controlled for an entire day. There are very few fur babies that are on three times daily dosing, but this has really been working for Corky for three months now.

[addy]

I did the Happy Dance with Zoe and Koko last night!!!!!!

I love you both to death!!!!!

GOOD NEWS IS THE BEST


Hugs,
Addy, Zoe and Koko

[lulusmom]

How did I miss such a great report on the Corkster? I am so happy to hear that things are going much better and that all of his test results were excellent. That's pawesome!

[labblab]

I wanna join the celebration, too!!! HOORAY for Corky!!!!!!!

:) :D :) :D :) :D :) :D :) :D :)

Marianne

[Harley PoMMom]

I want to join the others in this celebration! :D Great job Terri!!! Sending huge and loving hugs for you and Corky.

[mypuppy]

:)
I am not staying out of this party either. Yehhh Corky and Terri.

We love you both dearly.

Xo Jeanette and Princess

Ps: "paw some" haaaaa. Glynda always kills me with these, in a good way...:D

[Sabre's Mum]

Fantasic news!!!!

Angela and Flynn

[mytil]

Big smiles all the way 'round.

T.

[littleone1]

Corky and I thank each and everyone of you for celebrating this good news with us. You've been with us a long time and have really helped us get through so much.

We love all of you, and we are sending huge hugs, lots of kisses, and tons of love. Thank you all so very much.

[Squirt's Mom]

Late to the party but.....


WOOHOO!!!!

[littleone1]

LOL!!! The party is still going on! :D Corky and I still love you!

[Dollydog]

That's great news....hugs for the both of you! :D :D

[littleone1]

Thank you JoAnn.

[marie adams]

yeah!!!!!:):):):)

[Maya]

That's brilliant news! I'm so pleased for you both.:)

[littleone1]

Thank you Marie and Leah.

[Franklin'sMum]

Great news Terri! :)

I'm so very happy for you both :) Hugs to you my friend, and ear scritchies for the Corkster :D

Jane, Franklin and Angel Bailey xxx

[littleone1]

Thank you my friend. I'm sending hugs back to you and lots of belly rubs for Franklin. Corky loved the ear scritchies.

[littleone1]

Corkster is at it again. He now has ear infections in both of his ears. I just started his meds.

[Roxee's Dad]

Oh no:( The poor Corkster. Hope he feels better soon.

[addy]

Oh Terri,

I am hoping our little trooper gets better real soon. Always something with our pups.

Hugs and kisses and prayers for a quick recovery.

Love,
Addy

[apollo6]

Dear Terry
sending prayers that our Corky gets better.
Hugs to you and Corky

[addy]

Hi Terri,

How is our little boy doing? Are Corkster's ears getting better?

I hope you are both okay.

Love,
Addy

[littleone1]

Hi Addy,

Thanks for checking on us. Corky's left ear is much better, but I'm still getting alot of stuff out of his right ear. Since Dr. R. knows Corky so well, instead of treating his ears for the normal 7 days, Corky has to be treated for 14 days again. Our little boy is not a happy camper, as he has to have his ears cleaned twice a day with a medicated ear cleaner, and then the medication has to be put in twice a day.

I'm doing good. The meds are wearing on me. I've had to write all of the times down again. I'm not getting old! :D:D

Also, thank you John, and thank you Sonja for your prayers.

[mypuppy]

Hello my dear and missed friend,
I'm sorry to hear the Cork's ears have been acting up lately. he and Princess must have called each other cause she is also just getting over a very nasty one. vet put her on new ear drops and they worked wonders. It is always her right ear with her, always. She doesn't enjoy getting them cleaned twice a day either but sits very still for it, thank God. I hope Corkys infection will clear up soonest. I'm sending you my warmest and most loving regards and the same for my Cork. We are long overdue to talk. hopefully soon, husband's been away on military training and have about 5 days to go still. trying to run a tight ship with the girls--lol.

love ya both dearly. Xo Jeanette

[littleone1]

Hi my dear friend,

I think Corky and Princess did talk to each other. I'm glad that Princess's infection has cleared up. Corky's is getting better.

I actually tried to call you this morning. I didn't leave a message because your answering machine never kicked in. Talk to you soon.

(((HUGS))) for you and lots of belly rubs for Princess.

Luv ya bunches.

Terri and Corkster

[mypuppy]

Hi again,
Aw, Im sorry I missed your call yesterday. I checked my machine and you were right, it was off. I can only guess my little one at work. She has become our switchboard operator lately. LOL. I actually just got back from Princess's stim, and need to run out again before kids get home. I have a gut feeling her post will be higher this time around. She has been showing those dreaded signs for a few days now, so you know how it goes...:mad: Need I say more? Will keep you posted and hopefully I can manage to return your call sometime next week. Thank you for your call.

love you tons. Xo Jeanette

[apollo6]

Dear Terry
Just checking in on you and Corky. Loved your comments.
Hugs Sonja and Apollo

[littleone1]

Thanks for checking on us Sonja.

Corky's ears are almost cleared up. He finishes his meds on Fri.

[marie adams]

Hey Terri,

So glad the Corkster's ear are all most cleared up and no more medicine. :)

I hope you are well also. Take care!! :):)

[littleone1]

Thank you Marie. He has 2 1/2 days left, and then he'll be a happy camper.

I'm doing good. I hope all is well with you.

[addy]

Hi Terri,

How is the Corkster? How are you?????

I am hoping we have no more ear problems for the little guy!!!!

Have a wonderful weekend dear friend. Happy Friday!!!!

Love,
Addy

[littleone1]

Hi Addy,

The yuks are gone!:D I'm also hoping he doesn't have anymore problems with ear infections.

I'm doing good. Corky's right hind leg is really bothering him. The last two mornings, when he tries to go fast on his walks, his right hind leg is very stiff, and goes every which way. Since the X-rays didn't show anything unusual, I'm wondering if he could possiby have a soft tissue injury, as this wouldn't show up on X-rays. Other than that, he's really doing good. His CCD seems to be under control.

I hope all is well with you and Zoe.

Take care my dear friend, and have a wonderful weekend.

[apollo6]

Glad to hear some good news about the Corkster.
Hugs Sonja and Apollo

[addy]

How is my favorite duo doing?

Happy Memorial Day Terri and Corkey.

I hope you have lots of walks and belly rubs.:D:D:D

Terri, did you start Corkey out on compounded Trilostane? we have a compounding pharmacy five blocks from my house, Pet Apothecary. I was going to order from Diamondback if whichever vet I see will write the script. I knew many of our members used them (you included) and I don't know anything about the one near my house.

What is your opinion? Dr. Allen from Dechra had told me a few months ago to do one mg per pound and round down to the nearest capsule to start Zoe. That would mean 10mgs only. Dr. Peterson said 15mgs. She weighs 18.5 pounds.

Love ya,
Addy

[littleone1]

Hi my dear friend,

Happy Memorial Day to you, too.

Corky's been a little under the weather. For a few days he didn't eat very much and got sick yesterday. I knew it wasn't due to his cortisol level. This morning, he finally ate good for me.

Corky started out with 20mg of Trilo. His IMS started him on a low dose. I think that when Dr. Allen mentioned the 10mg a day, he was probably referring to Vetoryl. The compounding pharmacies do not make 10mg of Trilo, as the name brand comes in 10mg. I personally think that with Zoe weighing 18.5 pounds, that 15mg would probably be a good place to start, as this is not quite 1mg/pound.

Since you have a compounding pharmacy near you, I would get pricing from them and Diamondback. I trust Diamondback.

Take care my friend. Give Zoe lots of belly rubs from me.

[addy]

I am so sorry to hear Corky is not feeling up to par.

He better get better really fast or how will he eat hamburgers and brats and hot dogs from the grill Monday?:D:D:D

Whenever we have a barbecue my two go starking raving NUTS over the food smell:D Koko is just as bad as Zoe and he doesn't have Cushings:eek::eek::rolleyes:

I hope my nephew gets better real soon.

Love,
Addy

[apollo6]

Sorry to hear about Corky. Hope he feels better.
Hugs Sonja and Apollo

[Harley PoMMom]

I am so sorry to hear that our dear Corky is not feeling like himself. Will be hoping and praying that this issue will resolve itself really fast.

Sending huge and loving hugs to you both, Lori

[Squirt's Mom]

Hi Terry,

Glad to hear that Corky ate well this morning and I hope he is over whatever had him off his feed. I can well imagine how worrisome that was for you. :(

Wishing you and Corky a great Memorial Day! That cookin' Addy talked about made my mouth water! :D

Hugs,
Leslie and the gang

[littleone1]

Thank you my dear friends.

Corky and I just got back from the vet's. Corky had an accident in the house last night and this morning. This morning while we were walking, Corky was dribbling after he went potty. Corky is now taking Baytril for a UTI. :( Dr. R. mentioned that dogs with cushings could suddenly develop diabetes, but he doesn't feel that this is the case with Corky. Once he gets the lab results back, we'll know if there is sugar in his urine. He doesn't think there will be, as his last labs were good. I'm so glad that Dr. R. and Dr. H. send each other information about Corky. I have the best of two worlds with them. Dr. R. did say that Corky's ear infections are cleared up. :)

I'm still looking for that Merry-Go-Round ride, Addy. :)

I hope all of you have a wonderful Memorial Day weekend. Corky's going to have his steak on Monday.

Corky and I love all of you. (((HUG))) for you, and please give your precious fur babies lots of belly rubs from me.

[MBK]

Hi, Terri.

Sorry to hear about Corky's UTI. Poor little guy! At least you were able to get him in to the vet and on an antibiotic quickly! Alivia was released from the hospital following her pancreatitis with Baytril. She did well with it, so hopefully, Corky will be good as new really soon.

I hope the rest of your weekend is happily uneventful!

[Squirt's Mom]

Hi Terri,

That Baytril is good stuff, Maynard! :p Corky will be feeling much better real soon, just in time for some of that good ole grilling!

You're such a good mom.

Hugs,
Leslie and the gang

[addy]

Geeze Louise, Terri, that Merry Go Round is something else!!!!!!!!

I don't know which ride is worse, the Merry go Round or the Roller Coaster!!!!:D:D:D

Thank goodness the antibiotic will clear things up for our little trooper. And he is such a trooper. Poor guy:(:)

Make sure to give him extra belly rubs from me and I think you are going to need a bottle of Mary Beth's Chocovine.:D:D:D

I am so sorry dear friend. I know you are worried. Hang in there.

Love and Hugs and prayers and everything good I can possible send your way.

Love,
Addy

[littleone1]

Thank you Addy, Leslie, and Mary Beth.

I'm just glad that I knew what was going on with Corky. Two years ago when he started doing this, I had no idea what it was. That's when Dr. R. found out that he had 2 UTIs. He was also put on Baytril then. One of his UTIs was a difficult one to clear up, but the Baytril worked great for Corky. I'm so thankful that Dr. R. squeezed him in today. He said that Corky is definitely high maintenance.

Our Corkster is definitely a little trooper. I definitely want to get off of the roller coaster. :D A good stiff drink sounds good to me. :D