Corkster - adrenal tumor/3x daily trilostane (Corky has been released)

[littleone1]

Thank you so much, Lori. I really appreciate your very kind words.

Most of the redness is on his front paws, but there are a couple of his hind paws that have the redness.

Luv ya.

[clydetheboosmom]

Terri -

I can't add much, but I can say that I am thinking of you guys and sending good, positive prayers and thoughts your way, always.

Love and hugs -

Lynne, Clyde & Bailey

[Casey's Mom]

Hi Terri, hope you and the Corkster are doing okay - that redness on the nail bed is a puzzler. They love to keep us on our toes don't they?

Love and hugs,

[littleone1]

Hi Louise,

Thank you for your positive thoughts. I know that when you think that everything is going well with our precious babies, there seems to be an obstruction in the way.

I'm hoping Munchie will be fine and won't have any additional issues.

I'm also thinking positive thoughts.

[littleone1]

Hi Lynne,

Thank you so much for your good positive thoughts and prayers.

I hope all is going better for you and your furbabies.

[mypuppy]

Hi my sweet friend Terri,
My thoughts and prayers, love, concern and friendship go out to you and my little nephew. You both certainly deserve a break, so I will be wishing that and all that's good so he can get back to being himself again. And remember, there's always my shoulder to cry on, no matter what, but we must remain positive and continue to keep the faith. God loves you and Corky and so do I....Take care of you both. xo and tightest hugs ever, Luv ya, Jeanette and licks from your very hungry niece, Princess--lol (after all, we've got to make time to laugh throughout all this, so shoulders back, chin up and SMILE...:):):):)

[littleone1]

Hi my dear, sweet friend, and LiL Sis.

Your nephew and I thank you so very much. I've already cried on your shoulder, and I might do it again. Please know that I'm always here for you and my niece, Princess.

God love you. You are very special in my life, as are my other special friends here.

[Roxee's Dad]

Hi Terri,
Keeping you both in my thoughts and prayers. Hope the Corkster is still having fun and enjoying himself.

[Franklin'sMum]

Hi Terri,

I'm so sorry to hear that Corky is having some extra issues for you to worry about. I've read that doggie cataracts don't cause blindness like they do in people, and Bailey has had cataracts for a few years now, and he can still see people and pups on the other side of the street when he's inside on the couch. He kindly lets Mum and Dad know, by scaring the snot out of them :D:p:D

Hope your vet can figure out the nail issue,

Love from
Jane, Franklin and Bailey xxx
________
Arizona Marijuana Dispensaries (http://arizona.dispensaries.org/)

[littleone1]

Hi John,

Thank you for your thoughts and prayers. The Corkster is still enjoying things. He loves his long morning walks, or should I say his morning runs.:D He takes off running when we go out in the morning. He goes strong for just about an hour every morning. I keep telling him that I'm too old to run!:D

[littleone1]

Hi Jane,

Thank you. I feel better knowing that cataracts won't cause blindness in our furbabies. I'm hoping we can find something out about his nails. It's back to doing more research!:(

There's always something to worry about with our guys and girls.

Take care.

[littleone1]

Hi Everyone,

I just put a picture of Corky's nails on one of his paws.

Terri

[Nathalie]

Hi Terri,

I just took a look at the nail picture - I think this just looks like what one of my Sophies nails looked like and I also had a foster girl with the same issue on all her nails. However, its a bit hard to see in the picture as I am not able to enlarge it. I would like to get a closer look at this. I am going to send you a PM.
Nathalie

[littleone1]

Hi Nathalie,

I just responded to your PM about clicking on the picture. Since it didn't enlarge for you, I'll try to enlarge it and send it to you.

Thanks for letting me know that Corky isn't the only that might have this issue.

[Nathalie]

Got the picture - way better - I was able to zoom right in.

That is exactly what one of Sophie’s nails looked like.
The foster girl, Nelle, I mentioned earlier - all her nails looked like this.

How are the Corksters liver values?

When I showed Nelle's nails to my holistic vet at the time she said, if I remember correctly, it is a symptom that can occur when the liver is in poor health or has to work extra hard.

Now I can't point you to any documentation that supports this statement. I think it is possible, after all certain deficiency’s in people manifest/health issues itself in hair/nail abnormalities.
All I know is that Sophie's nails went back to normal after her dental and being on Milk Thistle. Her liver values where slightly elevated.

Nelle's nails took more then 6 months to slowly return back to normal.
Nelle was full of toxins do to HW treatment, liver values elevated and had sever dental disease and was 'just' in overall poor health when she got here.

Terri, please let me know what you find out about this in your research - I would be very interested to know.

Nathalie

[littleone1]

Hi Nathalie,

I'm glad the picture was better. Corky had a full blood work-up done on March 17th. His liver values were all in the normal range. His kidney values were elevated, but weren't too much above the high end of the range.

It could be possible that it is some kind of disease or fungus. A very dear friend sent me a link, which I have now copied, and I'm going to take it to my IMS on Monday. I will also let her know about the information you gave me. In one of the articles I read, it could possibly be secondary to hypothyroidism and cushings. At least I now know what information I am looking for.

Thank you again.

[littleone1]

Hi everyone,

I just got a call from Corky's IMS. Besides the discoloration of his nails, Corky doesn't show any signs of having bacteria or fungus of the nails. She did say that I could give him milk thistle to see if it would help. If I see any changes, I am to give her a call. I'm back to the waiting game again.:(

Terri

[Harley PoMMom]

Hi Terri,

Oh this waiting game just...well...sucks! Alot of members use milk thistle and swear by it. I've read many articles about its benefits also, I sure hope it helps our Corky.

Love and hugs,
Lori

[forscooter]

Hi Terri,

I hope the milk thistle helps and I wish I had some thought on this nail thing, but I have no clue. So how's that for helpful??!!:o

But I did want to check in and see what the update was and I promise I will cross everything in hopes that it helps.

Lots of love and hugs to you both! Beth

[littleone1]

Hi Lori,

Bless your heart. This waiting game definitely does suck. (Are we going to be sensored?:)

I don't know how much more our Corkster has to go through. I hope the milk thistle helps.

Nathalie, thank you for mentioning the milk thistle.

[littleone1]

Hi Beth,

Thank you for checking in on us. Not to worry about being helpful about this, as I don't know if anyone has a clue as to what's causing it.:(

I am now wondering, which I just thought of, if it has anything to do with the stains he now has under his eyes from his tear glands. I have to see if I can find any information on discolorations. I wonder if it might be related to something he's eating or meds he's taking.

Love and big hugs from the Corkster and me.

Terri

[Nathalie]

Hi Terri,

I truely believe that without the Milk Thistel Phillip's liver would have gone down hill with the high dose of Lyso he is taking.

His ALT actually returned to within normal range.

My recommendation would be to use Milk thistel tincture instead of capsules. Tincture is more easily absorbed.

Best Wishes,
Nathalie

[littleone1]

Hi Nathalie,

Thank you for this information. I will get this tomorrow for Corky.

I guess it's possible that since his cortisol levels keep increasing, even though his liver enzymes were in the normal range last month, that this, along with the mass on his liver, has put an extra strain on his liver.

[frijole]

Terry, got me on the milk thistle and the nails... hope it works! I give Haley milk thistle and it did help lower her alk phos. So it can't hurt! Kim

[littleone1]

Thanks, Kim.

It's definitely worth a try. I would do anything to help Corky.

[littleone1]

Just a quick update on Corky:

Since he's been taking the milk thistle and the increased dose of Trilo, his nails are not as red, and his appetite has definitely decreased. He still eats his 2 hearty meals a day, but he is not trying to get extra food and biscuits.

[Harley PoMMom]

:)
Yaaa!! :)

[littleone1]

Thanks, Lori.

I know I've been so worried about my Corkster.

[MiniSchnauzerMom]

Terri,

Glad the Corkster has shown an improvement and hopefully you can relax a bit now. Hugs to you and Corky.

Louise

[littleone1]

Thank you so much, Louise.

I hope I can relax now. This has definitely been a long roller coaster ride. I use to love roller coasters.:D

[Nathalie]

Excellent news!:)

Nathalie

[littleone1]

Thank you, Nathalie, and thank you so very much for your help. I feel much better now. Sometimes I think I'm being over-protective of Corky.

[mypuppy]

Hi again my dear friend,
So glad Corky's nails are starting to clear up. It's definitely a big load off your mind. BTW, one can never be TOO overprotective of our babies. I'm the same way with my human ones and definitely with my 4 legged one, so do not change, ya hear. Tight hugs for both of you. xo Jeanette ps: I never liked roller coasters and never will. LOL...

[littleone1]

Hi my very dear friend,

Thank you. I do feel a sense of relief. I know we watch all of our babies very carefully.

Lol!:D I don't think I like roller coasters any more.

Luv ya bunches.

[John II]

Hi Terri,

Good news about Corky!
I think we're all sick of rollercoaters - I'd like a nice calm merry-go-round myself. :)

[Squirt's Mom]

Hey Terri,

So glad Corky's nails are improving!

One of Squirt's shattered the other nite when I was trimming them and it freaked me out! :eek: I carried her for 2 days for fear of contaminating that toe. :rolleyes:

His clinical signs are improving, too! YEAH! You are such a good mom so of course you are over-protective....it's our job. ;) We just turn around time after time and get right back on that roller coaster, don't we? :p

Hugs,
Leslie and the girls - always

[littleone1]

Hi John,

Thank you. I agree with you, it would be nice to be on a nice slow merry-go-round.:)

[littleone1]

Hi Leslie,

Thank you so much. I have a feeling the roller-coaster ride is going to continue.:( We keep trying to do the best we can possibly do.

I know we have to be protective of our babies. I understand completely how you felt when Squirt's nail shattered. I've been afraid to cut Corky's, until his nails are back to normal.

Take care. I hope all is going well.

[littleone1]

Hi everyone,

I just got Corky's 30 day stim test and senior wellness test results.

His post stim was 5.3, which is a little lower than it was last month. This is the first time in a few months that it actually went lower instead of rising. Since the 31mg a day with the twice a day dosing is working for him, Corky will be staying on the 31mg a day, getting 20mg in the A.M. and 11mg in the P.M. He doesn't have to go back for a stim for 3 months. Hopefully we can make it this time.

His electrolytes were all in the normal range. His BUN is slightly higher than the last time. It was 43, with a reference range range of 6-31mg/dl. His creatinine stayed the same at 0.8 with a range of 0.5-1.6. His BUN creatinine ratio is high - 54, with a range of 4-27. The only other thing that was high was his triglyceride level, which was 331, with a range of 29-291. For some reason, this fluctuates. The last time it was checked, it was 207, and the time before that, it was 490.

His nails look so much better. Even the tech commented on how much better they looked. He will continuing taking the Milk Thistle, as this is also working for him. Thank you so much for the information on this Nathalie.

I'm quite pleased with his results.

[Nathalie]

Hi Terri,
congrats on the good test results!!!

"P.M. He doesn't have to go back for a stim for 3 months. Hopefully we can make it this time."

Good luck ;) 2 months is the longest for us between stim's:)

I checked Sophie's nail today and we are still doing good too.

Glad things are looking good,
Nathalie

[Harley PoMMom]

Hi Terri!

I am so happy for you and Corky, and I know you are both happy and relieved that his stim test results were good and that his nails are much improved. YAAA!!!

Love and hugs,
Lori

[littleone1]

Hi Nathalie,

Thank you so much. I know the last time we were suppose to go back in 3 months, we only made it 6 weeks. I'm thinking positive thoughts this time since his cortisol level actually dropped.

I'm glad Sophie's nails are still doing good. Thank you again for the information.

[littleone1]

Hi Lori,

Thank you again my friend. We are both very happy, and I'm very relieved.

[littleone1]

I forgot to mention that Corky will not have to get any more vaccines. Due to his age and his medical issues, his IMS totally agrees that he shouldn't get any more shots. Our county animal control does grant a waiver for dogs getting rabies shots due to this. Also, I'm glad I cut back on Corky's Soloxine. His T4 improved. It was 2.1 this time, with a reference range of 1.0-4.0 ug/dL.

[Nathalie]

Good for you for getting a waiver!!!:D and good for your IMS for having educated her/himself - yeah.

Terri, is that 2.1 a T4 or Free T4?

Nathalie

[frijole]

Congrats to you and the Corkster!!! :D:D:D:D

[littleone1]

Thanks Nathalie. I really feel that I have a very special IMS. Corky has been going to her for over a year now, and she's been great.

The 2.1 is the T4. We didn't do the Free T4 this time, as he just had it done about 3 months ago.

[littleone1]

Thanks Kim. I think I'll finally be able to get a good night's sleep!:D

[gpgscott]

Hi Terri,

Sounds very good, I am glad you are suspending the vaccines, no need to stress the Cork un-necessarily.

Hope he is happy and enjoying himself.

Scott

[frijole]

Thanks Kim. I think I'll finally be able to get a good night's sleep!:D

Take every one of those you can get! Its hard I know.. but you are doing a great job. Hang in there and hug the Corkster for me!

[littleone1]

Thanks Scott.

The Corkster is really enjoying life right now. He loves his long walks in the morning and his rides in the afternoon. He's really doing good. It's great to see him this way.

Not having to have any more vaccines is definitely a plus, as he is really stressed when he has to go to his vet or his IMS.

Take care.

[littleone1]

Thank you so much. I feel so good this evening that I treated myself to salt and vinegar chips. I know it's a no-no, but I feel such a sense of relief. It's been a long, hard road, but I would do it again in a heart beat for the Corkster. He is definitely worth it and then some.

[Nathalie]

" The 2.1 is the T4. We didn't do the Free T4 this time, as he just had it done about 3 months ago. "

Terri, that 1.0-4.0 ug/dL range is for a dog not taking thyroid replacement.
When you test in that 4-6h post pill window you are testing when the Soloxine peaks after that it keeps on dropping.
Therfore ....

“Optimal therapeutic response levels should be in the upper 1/3 to 25% above the upper limits of the resting optimal ranges at 4-6 hours post-BID thyroid medication.”

So if 2.1 was a T4 I am confused why your IMS suggested lowering the Soloxine. Even with slight differances between labs ranges 2.1 is certainly not high.
These are the ranges you are looking for - for a dog receiving thyroid replacement..

TherapeuticOptimal Levels

T4 2.20 – 4.50 mg/dL FT4 0.70 - 2.00 ng/dL
T3 40 – 70 ng/dL FT3 1.6 - 3.5 pg/mL

compared to the ranges for a dog that is not on thyroid replacement for a dog approx. 8 years or older:

T4 0.80 – 3.80 mg/dL
Free T4 0.60 – 2.50 ng/dL


So the Corksters T4 is right at the bottom at the therapeutic range for T4 – I personally would not lower the dose but would check with your IMS why she does not want the Corkster in the upper 1/3 to 25% above the upper limits of the resting optimal ranges.
I really would be interested in her reasoning.



Nathalie

[littleone1]

Hi Nathalie,

Now I'm getting confused again. Corky's T4 results were above 2.1 before, but he started having issues being on 1 pill twice a day. I'm the one that made the decision to lower the dosage, and put him back on the dosage he was taking for years. His IMS agreed with it. His previous T4 was 1.3, and for Corky going back to 1/2 pill twice a day, it actually increased his thyroid level. I need to go back through my thread to see what issues he was having. My memory is not that good any more. Corky is not showing any signs that his thyroid level is too low.

Terri

[Nathalie]

Sorry, adding confusing was not my intention.

Just wanted to put the info out there.

Perhaps Corky is one of the dogs that feels best in the upper 1/3 range. After all these are just ranges.
What is Corky's weight and what was the dose before the increase and what is the decreased dose now?

If you saw definite symptoms of hyperthyroidism such as excessive drinking, restlessness etc. on the old dose then yes a decrease might be in order.
It is possible that a dog being oversupplemented to test hypothyroid because the body can increase thyroxine turnover rate and excrete it faster to avoid thyrotoxicosis.

Personally I am not putting as much value in a T4 compared to a Free T4 for monitoring as the Free T4 is more specific and tells you how the dog actually utilizes the Soloxine.
If you stick with a Free T4 you are also able to compare apples with apples.

Phillip for example is on 0.4mg and his Free T4 is slightly above the optimal therapeutic range at 2.25 ng/dL and seems to be feeling good at that number.

Nathalie

[littleone1]

Hi Nathalie,

Not a problem. Corky weighed 18.13 pounds on Tuesday.

When he originally started taking Soloxine about 10 years ago, he was taking 1 pill twice a day. Four months later, the dosage was dropped to 1/2 a pill twice a day. In January of this year, his dosage was increased to 1 pill twice a day.

Corky did start having issues after a few weeks on the increased dosage. He was drinking more water, was eating more, and was very restless. These weren't related to his cortisol level. That's when I decided that I was putting him back on the previous dosage. Since I did this, he's been doing good. I let my IMS know what was going on and what I did. She was fine with it.

In January, after taking 1 pill twice a day, his FreeT4 was 3.2, which was above the range.

Thanks again for all of your help.

[gpgscott]

Terri,

It is my understanding on this that the TSH (thyroid stimulating hormone) is important. This may be the other T number that Nathaline is referring to.

TSH is secreted to stimulate the natural production of thyroid and high TSH with a low or low 'normal' circulating thyroid is indicative of primary thyroid deficiency.

Moria was low thyroid for a while and it was not until she began to exhibit signs of laryngeal issues that we became aware of it.

Scott

Ok, Iv'e looked at this a bit, and If I am getting it right without a TSH number you really don't know much.

[SasAndYunah]

Hi Terri,

We so often look at the dog's behaviour to determine how they are doing... But when I read that you had salt and vinegar chips, that was a clear indication that Corky is doing great :p We're very happy for you and Corky!

Hugs,

Saskia and Yunah :)

[littleone1]

Thank you for this information, Scott.

When Corky goes back for his next stim test, I will definitely have his Free T4 checked again to see what his level is. I always have his electrolytes, liver enzymes, and kidney values checked. I always feel better when I know exactly what is going on with the Corkster.

[littleone1]

Hi Saskia,

LOL! I had to have a special treat for myself. Corky is really doing good.

I hope you are doing better. Give Yunah a big hug from me.

[gpgscott]

Thank you for this information, Scott.

When Corky goes back for his next stim test, I will definitely have his Free T4 checked again to see what his level is. I always have his electrolytes, liver enzymes, and kidney values checked. I always feel better when I know exactly what is going on with the Corkster.

Terri,

What I am saying is you need to ask about TSH.

Scott

[littleone1]

Hi Scott,

I will ask my IMS about it.

When I spoke with Dr.Dodds before, she recommended the T4 and the Free T4 if the whole thyroid panel wasn't done. If the base T4 level is low, the THS test can be used as a diagnostic tool to confirm hypothyroidsm. I might give Dr. Dodds a call next week and ask her about it.

Terri

[Franklin'sMum]

Hi Terri,
Wonderful news on the Corkster!! I'm so glad he's feeling better.
Love and puppy kisses,
Jane and Franklin xx
________
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[littleone1]

Hi Jane,

Thank you so much. I'm glad my Corkster is doing good.

I hope all is well with you and Franklin. Give Franklin a hug from me, and Corky is sending kisses to you both.

[Harley PoMMom]

I believe that once a pup has been diagnosed with hypothyroidism and is being treated then the only tests one needs to monitor is the T4 and the Free T4.

Thanks Nathalie for supplying these questions and answers ;):) I have them saved on my computer for my own reference.



I previously had emailed Dr. Jean Doods with some questions and thought I post my questions and Jeans responses here as well for anybody who might be interested.

“Optimal therapeutic response levels should be in the upper 1/3 to 25% above the upper limits of the resting optimal ranges at 4-6 hours post-BID thyroid medication.”
Explanation:
Geriatric Therapeutic Optimal Levels:
T4 2.20 – 4.50 ug/dL
FT4 0.70 - 2.00 ug/dL
T3 40 – 70 ug/dL
FT3 1.6 - 3.5 ug/mL

Question: How often should I have his thyroid function tested and what tests should be done?
Answer: Every 6-12 months; test T4 and freeT4.
Question: I have read that we should test not only for T4 but also Free T4 – is this correct and what does the Free T4 value in conjunction with the T4 value supposed to tell me?
Answer: Definitely, because freeT4 is the biologically active tiny fraction [0.1 %] of total T4 .
Question: How to convert T4 value from nmol/L to ug/dL
Answer: you must divide the nmol/L by 12.87 to convert it to ug/dL

Nathalie


Hi Scott,

I will ask my IMS about it.

When I spoke with Dr.Dodds before, she recommended the T4 and the Free T4 if the whole thyroid panel wasn't done. If the base T4 level is low, the THS test can be used as a diagnostic tool to confirm hypothyroidsm. I might give Dr. Dodds a call next week and ask her about it.

Terri

[littleone1]

Hi Lori,

That was my understanding, also. Thanks for this information.

[littleone1]

Hi everyone,

I know it's been awhile since I've been on the forum. I was taking a much needed break. It's going to take me awhile to catch up on all of the threads.

Corky is still doing good on the twice a day Trilo dosing. His nails are almost back to normal. Unfortunately, along with his cataracts, he is also losing his hearing. Recently, he has really been shedding. Nothing is coming out in clumps, and there are no bare spots like he had before he started his Trilo. I'm hoping we can make it the 3 months before his next Stim in August.

[sunimist]

Hi Terri!

Glad to get an update on the Corkster! So glad everything is stable, and hope it just keeps getting better!

(((HUGS)))

Shelba and Suni

[labblab]

Oh Terri, it is so good to hear from you guys!!!! I was just thinking about you both yesterday and today, and wondering how things are going. I'm sorry about Corky's hearing. This aging "stuff" is really no fun -- for humans or doggies...:o

And boy, I can sympathize with the shedding. My Peg is shedding up a storm. I keep brushing her a couple times a day, thinking that surely there CAN'T be any more loose hair. But it just keeps acomin' no matter how often I brush her. The good part is that she is looking very slim these days, after getting rid of all that hair! :)

Please give Corky some hugs for me, and it's really good to see you back here!
Marianne

[Squirt's Mom]

Hi sweetie!

Glad things are going ok for you and Corky! I agree with Marianne all the way...aging ain't fun for any of us but with your loving care Corky will manage just fine I know.

Big hugs!
Leslie and the girls - always

[littleone1]

Thanks Shelba. I also hope that things keep getting better with his treatment.

[littleone1]

Hi Marianne,

Thank you so much for thinking about us.

I know that old age doesn't come alone for any of us. I was also recently diganosed with cataracts. I'm just glad that Corky is doing as good as he is. He's still very active and goes for his 2 1/2 to 3 mile walks every morning.

His shedding might have alot to do with his age and the temperatures here.

Corky loved the hugs.:)

[littleone1]

Thanks Leslie. Corky definitely gets lost of loving care. He's always close by. He follows me everywhere. I now know it's because of his eyesight and his hearing. He needs to know where I am at all times.

Take care.

[littleone1]

Hi Everyone,

I just added a picture of Corky. Recently, Corky's white fur on his neck and chin have turned colors. The color is more on the orange side. It's not heat rash. I have no idea what it might be. If anyone has any ideas or thoughts, I would really appreciate the input. It doesn't bother him, but it bothers me. If it doesn't start clearing up, or if it gets worse, I am going to make an appointment with his IMS.

Thanks for your help.

[Roxee's Dad]

Hi Terri,
Does the Corkster wear a collar? Is it possibly the die from the collar bleeding off?

[lulusmom]

Hey Terri,

I was going to ask the same thing....does the Corkster wear a collar? I have two very white Maltese dogs and their orange stains are due to tearing and their saliva from licking their feet and smacking their lips.

[littleone1]

Hi John,

Corky does wear a collar, but his is black. He only wears it when we go for our morning walk. That was my first thought, that the collar might have caused it, but it's also under his chin and his collar doesn't touch his chin. There is no discoloration on the collar.

Terri

[littleone1]

Hi Glynda,

Corky also now has stains under his eyes from his tearing. He's had them for over two months now. His are more on the brown side.

[mypuppy]

Hi my friend,
I really wish I had anything to help out with this, but do you think this could this be related to the nail discoloration issue he had a while ago? Don't know, but I understand how it could drive you bonkers not knowing what it actually is. Let me know what your IMS says if and when you bring Corky in. Hang in there, and I'm sure it will be nothing. Luv you both bunches. xo. J.

[BestBuddy]

Hi Terri,

I noticed you said that Corky had been shedding so I wonder if the orange color is new hair growth. Buddy's new hair after the Trilo came back a rather pretty orange color. He had it pretty much all over and I thought it was quite nice but after a few haircuts it reverted back to the normal white color. Neither the specialist or our local vet could tell me why, it seems it is just another one of those things that make you go hmmm.

Jenny

[littleone1]

Hi my dear friend,

It's possible it could be related to the nail issue. I just have to wait and see what happens. I'll let you know if I take him to his IMS.

Luv ya bunches. Give Princess a big hug from me.

[littleone1]

Hi Jenny,

Thank you for this information. This could be the reason for the orange color. Corky has just about stopped shedding, and it could very well be new hair growth. I know that when Corky's nails got so discolored, his IMS hadn't seen this before, and didn't know what it was. Thanks to Nathalie and her advice, they are just about back to normal.

I know that there are so many things that make us go hmm with Cushings. You helped put my mind at ease. Thank you.

[Harley PoMMom]

Hi Terri,

I've been goggling like crazy and can't find an answer for you. :( Altho Jenny's post about Buddy's hair changing color after the Trilo, I believe, could be what is happening to Corky also. Please keep us updated and keeping you and Corky in my thoughts and prayers.

Love and hugs,
Lori

[littleone1]

Thanks my dear friend. I appreciate your trying to find information about it. I've been searching on ask.com. I'm going to try the Mar Vista library. I hate the thought of putting Corky through extra stress by taking him to see his IMS now, as he has to go next month for his stim test and bloodwork. It could very easily be from the Trilo, as Jenny posted.

Thank you for keeping us in your thoughts and prayers.

Give Harley and Bear a big hug from me.

[littleone1]

Corky has to see his IMS next Friday. He now has a brownish-orange spot that fills in the whole area between his yes.:( She wants him to come in when the dermatologist is there. If anything more happens before then, I'm to bring him in sooner.

Terri

[littleone1]

We just got back from an hour long visit with Corky's IMS. His discoloraton spread. It is on the top of his head and going down his chest and stomach. There is now a brownish color. When I called this morning, his IMS wanted me to bring him in. She doesn't know what's causing it, but she will be talking to the dermatologist to discuss her observations. Corky might still have to see the dermatologist on Friday.

She did a complete blood chemistry panel and CBC on Corky. When she gets the results back, we'll proceed from there with any other tests. She also did an U/S. Corky's adrenal tumor has increased in size. When he had the U/S done in May, it was 3x2cm. Today, it was 3.5x2.1cm. It was 2.4x1.3 in Nov. There's a slight possibiity that Corky might eventually have to be switched to Lyso, since he is not able to have the surgery.:(

She also removed the cyst on his back as it had also grown in size.

There's never a dull moment.

[Squirt's Mom]

Hey Terri,

That discoloration is strange...I was hoping to hear there was a simple explanation...as I'm sure you were, too. Let us know what the IMS figures out. Any suspicion it could be a result of the tumor?

Does Corky still seem to be feeling well? Any resurgence of signs?

Let us know what the blood work shows and if they decide to switch him to the Lyso.

Hang in there, Mom, you're doing GREAT!

Hugs,
Leslie and the girls - always

[littleone1]

Thanks Leslie for your very kind words.

I was hoping that it would be something simple, but I guess it isn't. She doesn't feel that it is due to the tumor or his intermediate hormones, even though the tumor is definitely infringing on his blood vessels. Surgery is still the best option, but not for Corky. When I get his test results back, I will post the ones, if any, that are out of line. Hopefully, his blood work will continue to be good.

So far, he is not showing any of the clinical signs. There doesn't seem to be anything bothering him. He still loves his long morning walks, even in the heat. He'll roll in wet grass and run under the sprinklers when people are watering their grass. I always carry a bottle of water for him to drink and to cool him down. His IMS called him the Little Energizer Bunny today.:D

Thank you again Leslie.

[Casey's Mom]

Hi Terri, the best news is that he feels great and that's all that really matters right? Hope it all turns out well for you and the Corkster, he is such a cutie.

Love and hugs,

[littleone1]

Thanks Ellen. I know that I'm glad my Corkster feels good. He doesn't let too many things bother him. I'm hoping that this too will pass. I think he's a little cutie, too, but I could be just a little prejudiced!:D

[Bichonluver3]

Nope, terri, you are not prejudiced. He IS a cutie. So glad to hear that the Corkster is feeling fine.
Carrol & Chloe:)

[marie adams]

Hi Terri,

Not sure exactly where Corky's reddish fur comes from, but I know Maddie's fur has turned a reddish color and isn't black any longer. I also noticed the black on her face is going away and the tan color is taking over even on top of her head. Last Sunday I combed her before giving her a bath and her white collar of fur is now sooooo thin it is almost gone. I guess she is finally blowing her coat. I have finally noticed she is getting baby fine fur starting to grow on her belly--good thing because there isn't much left.:o:o

I think I read on some sight that their fur will change colors, but I cannot remember why they said this happens other than because they are a cushings dog--so maybe the medicine causes it--Maddie is on Lyso. I so long for her beautiful coat of fur, but I would give that up for more muscle in her hind legs.:D

Take care and I am glad everything else is going good for the both of you!!:)

[littleone1]

Thanks Carrol.

I'm glad the Corkster is feeling good other than the discoloration. I'll get the results of his blood work this morning. Then we'll take if from there.

[littleone1]

Hi Marie,

I'm not sure if Corky had blown his coat. Before he was diagnosed with Cushings, he lost alot of his fur. After he started taking the Trilo, his fur grew back in. It was also very fine and soft. The muscle weakness in his hind legs also went away. I hope that Maddie Girl's hind legs will also get stronger.

I guess it's possible that the discoloration could be due to the medication, but I don't know why it would happen so suddenly after his taking the Trilo for a little over nine months. We learn something new every day. Hopefully we'll be able to find out for sure what is causing it.

[Boxer_lover]

My Ben's fur changed from tan to black on the top of his head. His skin as also turned dark on his belly where they shaved him for is ultrasound. His fur hasn't grown back yet so I am not sure if that will effect the color or not.

Wendy

[marie adams]

I noticed Maddie's belly and skin where the dark fur is has gotten darker also. It seems like at first when we noticed the under fur was gone it was more pink or just lighter color and now dark, but then maybe it is the fine fur starting to come in and it is so fine it is hard to tell.

So true about learning something new with them everyday--You think you know most of it and something throws a wrench in it as they say.

Maddie has the sneezes right now--the vet's office says not to worry it could be allergies with the weather being so weird out here these last 2 weeks. She has never had allergies so the sneezing is new, but as long as nothing of odd coloring comes out of the nose and it is just clear they said don't worry for the time being--eating, drinking and everything else is good. :confused:

Have a great day!!!:)

[littleone1]

Hi Marie,

Isn't it amazing what we notice about our furbabies once they have Cushings, along with different things they get, such as allergies. Even arthritis can surface or get worse once the cortisol level is lowered.

I'm hoping that Maddie has a short allergy season.

You have a great day, also.

[littleone1]

I just got a copy of Corky's test results. There were only a few things that weren't in the reference range:

BUN - 40 Range - 6-31 mg/dl This was better than the last result, which was 43.
BUN/Creatinine Ratio - 40 Range - 4-27 This was also better than the last one which was 54.
Platelet Count - 415 Range - 170-415 10(3)/uL.

There is nothing in his blood test results that point to anything that caused the discoloration. Therefore, Corky does have to see the dermatologist on Friday.

[marie adams]

Hi Terri,

Well it is good on the test results; so maybe it does have something to do with the medicine over time that causes it, but you should know on Friday with the derm dr. Stupid side effects of medicine!!!:p

[littleone1]

Thanks Maria. I feel good about his test results.

I contacted Dr. Oliver to inquire about the possibility of increased intermediate hormones having anything to do with the discoloration. He responded very promptly, and recommended that I contact Dechra, as it could be due to the Trilo, although it is not something that is commonly seen. I just spoke with Dr. Allen at Dechra, and he didn't remember anything like this off the top of his head. He's going to research their data base to see if there were any other reports of discolorations.

[SasAndYunah]

Hi Terri and Corky :)

I was so pleased to see the results of Corky's test. The ones that were elevated, had come down even some more, so that's good news :) It must be strange to see the coatcolour change...but then again, we love them no matter what colour their coat changes into ;) My Yunah is becoming pretty grey around her muzzle ( I know, just a "natural" colour change and nothing to worry or wonder about) but I think she is even more adorable with her greying face :D And...she now better matches my haircolour :p

Give Corky some big hugs from us overhere and all the best to you both,

Sas and Yunah :)

[Bichonluver3]

Hi Terri!!
Good news on the test results:). Glad you contacted Doc Oliver. he has been very good with our questions also. What a man! Will be waiting to here what the dermatologist has to say.
Marie - we are in the California desert and my 3 are sneezing, coughing and hacking up a storm!
Terri - give the Corkster a big hug from us.
Love and tail wags,
Carrol & Chloe

[littleone1]

Hi Sas and Yunah,

I'm very pleased with Corky's test results.

I know what you are saying about the gray hair.:) Corky's been turning gray for awhile. I keep teling him that he's catching up to me.:D We do love them no matter what color their hair is. They're just so precious and such a big part of our lives.

I hope that all is going well with you and Yunah.

Sending special hugs for both of you. Take care.

[littleone1]

Hi Carrol,

Corky's test results were really good.

Both Dr. Oliver and Dr. Allen have really been good about getting back to me. I know that they are both very busy, but they have always responded very quickly by phone and e-mail.

I know that Jenny said that her dogs had the discoloration which was probably due to the Trilo. A member on another forum also had the same problem with one of her dogs that had been on Trilo for 11 months. Once her dog was switched to Lyso, the fur cleared up. Hopefully I will definitely know more tomorrow. Corky loved his big hug and is sending you a big wet kiss.

[lulusmom]

I have never heard that Trilostane could cause the coat to change color. :eek: Lulu is pretty bald so it's understandable that I never noticed a problem. :D

[frijole]

Hmmm... if it makes your hair darker I might just try some myself to see if it eliminates gray? :D:p

[littleone1]

H Glynda.,

I guess anything is possible.:( You just never know. I will be glad when Corky sees the dermatologist tomorrow. Something is causing it.

Even though Lulu is mostly bald, she is still so adorable.

[littleone1]

LOL Kim. :D If that were the case, I just might try it too.:D The only thing is that I wouldn't want the orange color!:rolleyes:

[Franklin'sMum]

Hi Terri,

I'm very happy Corky's fur discolouration seems to be accounted for, and nothing serious :)
Has Corky had a urine protein creatinine test run? It's just a pee test that the vet sends off. BUN is a kidney function value, as is creatinine.
Did your vet/IMS mention the results, or suggest further testing? Some elevations in these can be explained due to dehydration (even panting can cause dehydration) and high protein meals. I'm guessing Corky was fasted for the test, but apparently feeding a raw diet can cause elevations in BUN/Creatinine (Dr Jean Dodds).
What's the Corkster eating these days?

Hugs to you and Corky, my friend,
Jane, Franklin and Bailey xxx

[QUOTE=littleone1;36039]I just got a copy of Corky's test results. There were only a few things that weren't in the reference range:

BUN - 40 Range - 6-31 mg/dl This was better than the last result, which was 43.
BUN/Creatinine Ratio - 40 Range - 4-27 This was also better than the last one which was 54.
Platelet Count - 415 Range - 170-415 10(3)/uL.[QUOTE]

[littleone1]

Hi Jane,

Thanks my friend. Corky's IMS isn't concerned with his BUN and BUN/Creatinine test results, as his creatinine level is in the normal range. These results are better than the last ones. His creatinine level has been in the normal range for quite a few tests.

Corky has never eaten a raw diet. I personally don't believe in them. This is just my opinion. He eats low fat boiled chicken, ground beef, and ground turkey, which are rinsed after they are cooked, rice, sweet potatoes, and green beans, with a special meal every so often.

I'm waiting for the results from the dermatologist. As soon as I get them, I will post them.

Big hugs for you and Franklin.

[littleone1]

Corky's hair discoloration wasn't caused by the Trilo. He has a yeast infection which has to be treated with a medicated shampoo twice a week. When I get the shampoo, I'll post the name of it to see if anyone has ever used it.

Terri

[mypuppy]

OMG Terri,
As sorry as I am he has an infection I feel you must be a bit relieved it's only this and not something worse and that they figured out what it was. So glad the treatment is only shampooing. I think you can handle that and so can Corky. Lots of love for both. Xo Jeanette

[littleone1]

Hi my dear friend,

I actually wish I was able to give Corky an antibiotic instead of the shampooing! He does not like to get baths. Having to have one twice a week, for I don't know how long until I get the remaining information, is going to make me a lot grayer, if that's possible!:D I might wind up losing my hair from pulling it out!!!:D:D:D

Hugs to Princess. Luv ya bunches.

[mypuppy]

Oh no! I'm sorry. I thought it would be a simple fix. I guess having to shampoo a baby that doesn't enjoy bathing could be no simple task for mommy. Hang in there maybe now he'll get used to the idea. Don't worry about your hair. Xo J

[lulusmom]

Hi Terri,

I've been stymied with Corkey's change in coat color so I took advantage of the time I spent at home yesterday after oral surgery to do a little research. Lo and behold, I found a paper entitled Sex Hormone Dermatosis by William H. Miller, Jr., VMD, DACVD
College of Veterinary Medicine, Cornell University, that links coat color change to sex hormones. Adrenal tumors usually secrete an excess of sex hormones, then throw a drug into the mix that is known to elevate the sex hormones (Trilostane) and I think you may have your answer.

You can find the following excerpt at http://www.vin.com/proceedings/Proceedings.plx?CID=WSAVA2004&PID=8630&O=Generic


Adrenal Neoplasia

With a slow growing adrenal adenoma, the constitutional and cutaneous signs of Cushing's disease can mimic those seen with adrenal hyperplasia. With a rapidly growing adenoma or an adenocarcinoma, the clinical course and cutaneous signs usually are different. Constitutional signs and coat changes often are recognized simultaneously and the coat changes mimic those seen in gonadal sex hormone imbalance. Skin and coat changes seen include numerous comedones, coat color change, loss of primary but retention of secondary hairs on the trunk, and a patterned (focal and persistent) alopecia. The nature of the patterned hair loss depends on the animal's gender and the hormone in excess Females tend to develop flank and saddle hair loss while males have hair loss in the collar region, thighs, and ventrum.

[littleone1]

Thank you so much for this information Glynda. I know I've been trying to find any information I can about this.

First of all, I hope everything went well with your oral surgery.

I guess I will really need to see what happens with the medicated shampoo. I am making a copy of this link for my IMS and the dermatologist, the latter of which I have my doubts. Since there is a yeast infection, we'll try to clear that up.

I'm surprised that Dr. Oliver didn't mention this. I just feel so bad for my little Corkster. He's been through too much in his lifetime.

Thank you again so much for finding this information.

[lulusmom]

Terri,

The oral surgery went well and thanks to strong meds, I am relatively comfortable. I take advantage of times like this to milk it for all it's worth. I've got Gil waiting on me hand and foot. :D:p:D

I realize that Corky has been through an awful lot but if the coat discoloration is due to sex hormones, I honestly believe that it's simply a cosmetic issue that isn't causing him any discomfort or pain.

[littleone1]

Bless your heart.

I'm glad you are being pampered!:D You deserve it, and I really do mean that.

As long as Corky isn't hurting, I can deal with this. I don't care what Corky looks like as long as he is not in pain. He's still and always will be my precious, special, little angel.

[littleone1]

The shampoo that Corky is suppose to use is KetoChlor, but I lucked out and probably won't have to give him two baths a week, as my vet actually has the KetoChlor in a leave on lotion. It's suppose to work the same way. I know the Corkster will be a happy camper.:)

Dena asked me to say hi to everyone from her and Simon. She hopes to be back on the forum soon.

Terri

[mypuppy]

Thank goodness my dear friend,
The less stress for our Corky the better. Just the same let us know how it all goes for both of you. Warmest regards and much love always. Xo J.

[littleone1]

Thank you my very dear friend.

I feel better about this now. Corky's IMS called me a little earlier and told me that there was an antibiotic that can be given for this, but due to Corky's adrenal tumor, it would add more stress on the adrenal glands. We're going to try the lotion first.

Take care. Talk to you soon.

Luv ya bunches as always.

[marie adams]

Hi Terri,

Our poor babies it seems like this wonderful disease just keeps on giving--haha!!! Well I hope Corky takes well to the lotion. I would hate to have to give Maddie a bath twice a week--she so loves them--not. I use to take her to a place I could use a tub that was elevated so easier on me, but she just cannot get in the tub from the steps we used. So it has become a family affair to bath her in the backyard with warm water and her cute blowup pool which she hates, but will get in it with the famous COOKIES bribe.:D:D

I wonder if something more involved has been causing Maddie's fur to be redder (the black fur) in color. She has lost tons of fur all over in the last couple of weeks. She does have the original loss of fur under/behind her front legs (kinda like armpit area), belly, back of hind legs, and under fur. The only place I see re-growth so far is her belly---cute soft fur and possibly the under fur coming back.

Take care!!!

[Franklin'sMum]

Hi Terri,

Great news on the lotion front :):), less stress for Corky :) YAY!! (And less back pain for you :D) Did the derm vet say how long it might be before the infection clears up?
Hey, if memory serves, didn't Corky have a yeast infection on one of his feet? That turned his foot fur reddy/brown? Terri, I really hope that the KetoChlor works wonders, and quickly!
Please give the Corkster belly rubs from us,

Jane, Franklin and Bailey xxx

Side note: Marie- this is from Monica Segal's book, K9 Kitchen, pg 80,
Tyrosine is an amino acid. It's available in good supply in meats. skipping a little- Without enough tyrosine, a black coat can start to fade or take on a red/orange cast

Sorry for the slight side-tracking of Corky's thread, Terri :o

[littleone1]

Hi Marie,

Thank you. I hope Corky does well on the lotion. It is definitely less stressful for both of us.

When Corky originally lost his hair, it grew back in very soft and very fine. Eventually it all grew back in. You never know what's going to happen next with our furbabies.

Hugs,

Terri and Corky

[littleone1]

Hi Jane,

I am also hoping the lotion works well. I don't know how long it will take to clear up. I'm hoping it won't take too long. I just put some on Corky, and he didn't mind it. I have to wet his fur first and then massage it in. I'm not using it on his entire body. I'm just putting it on localized areas. I'll be putting it on 3 times a week.

Corky, as far as we know didn't have a yeast infection on his paws. The redness was actually under his nails. This is when I started giving him Milk Thistle, and it really worked to clear it up, whatever it was. Most of his nails are back to their normal color.

I don't mind the sidetracking on Corky's thread.

Give Franklin and Bailey lots of belly rubs from me.

[addy]

Interesting, Zoe had pinkish brown staining on her feet, I thought it was mineral spit from holding her Kong. Last week it dawned on me, she did not have the the stains any more. I wonder if the metronidazole got rid of it because it was red yeast?

At any rate, I am glad the discoloration did not have to do with Corkster's meds:)

Addy

[littleone1]

Thanks Addy. So am I.

I have a friend that has a Boston Terrier that had the same thing happen to her furbaby's nails. She is on Denamarin now, and since she's been taking that, her nails also cleared up. It's a mystery.

Take care, and I hope everything goes well with Zoe. I know I don't really post very much on other threads where our furbabies are not on Trilo, as I really don't have any experience with the other medications.

Take care.

Hugs,

Terri

[sunimist]

Just thinking bout you and Corky and sending some (((HUGS))). :)
Sure am learning something new about yeast infection from the Corkster, bless his little heart. Hope the topical works magic for the little guy.

Shelba and Suni~~

[Harley PoMMom]

Sending big hugs and kisses to you and Corky.

Love you both,
Lori

[littleone1]

Thanks for the hugs Shelba. They are greatly appreciated.

I'm also hoping the topical treatment works. I know I keep learning something new every day. I can't believe all of the different things our furbabies get.

The Corkster is such a little trooper. I'm hoping he doesn't get anything else.

[littleone1]

Thank you for the big hugs and kisses my dear friend. Corky and I really appreciate them. Just when you think that everything is getting under control, someone throws in a big monkey wrench.

We're sending big hugs and kisses back to you. We love you bunches. Please give Harley and Bear lots of belly rubs from me.

[marie adams]

Hi Terri,

We just learn more and more visiting here on this forum. I started reading up on yeast infection and it makes a lot more sense about why I would see reddish coloring on Maddie's paws between the toes. I just recently wondered why her one ear had more waxy looking stuff in it, and she continually had a reddish patch on her front leg on her white--this I thought was from rubbing her one eye that had a scratch on it, but I think all of this might have been a darn yeast infection. It all seems to have gone away so I think feeding her a much better diet (cannot believe it is that much better, but...) all the supplements and no grains might have been the answer. There was one site that suggested coconut oil. I will try to remember to cut and paste it later.

Here's hoping it all goes away for the Corkster!!!:D:D

[littleone1]

Hi Marie,

It's very possible that Maddie might have had a yeast infection. I hope it doesn't return.

Corky use to get yeast and bacteria infections in his ears. He hasn't had any infections in his ears since January. It's hard to tell what causes them. Most of Corky's infections in his ears were mostly due to his hypothyroidism.

I'd be very interested in the article you read. I know I have once again been doing a lot of research on the web.

Terri

[addy]

Addy's input:)

I did read grain feeds yeast so maybe if you omit grain from their diet, you are not feeding the yeast anymore, so less infections. Could make sense!!!!

I agree with Marie, every day we keep learning. Thank you Corkster!!!! But sorry you had to go through it:(

Addy

[littleone1]

Thanks for the information Addy. I'm going to check with Corky's IMS, as both his vet and IMS recommended rice as part of Corky's diet due the problem he was having with his bowel movements.

The Corkster says you are very welcome. He's glad that he can help others that might have the same issues. To him, this is a minor issue.

Terri

[marie adams]

Hi Terri and Addy,

Here is a link about natural ways to cure yeast infection--I am not advocating the product line, but it makes sense what they are saying. This is a different link than the one I saw the other day--was going to print the other one, but got side tracked with--darn, work--it was saying the same thing about the coconut oil and such, though.

http://www.natural-dog-health-remedies.com/dog-candida-remedies.html

If I find the other one I will post it also.

[marie adams]

This is another one I came across---not sure if it is advertising for the product or a little of both info and product--it is addressing humans not canines, but interesting. Didn't know this was a big problem in humans the way they explain it. I wonder if this might be an underlying problem to what ails our little ones when there is no explanation...just a thought!!

http://www.candidasupport.org/RESOURCES/comparing-candida-products/?gclid=COK_mdn0kKMCFRk6agod0znvtw

[littleone1]

Thanks for the links Marie. There are so many possibilities and theories for treatment. I know we sometimes get overwhelmed with all of the information we have to digest. It's always good to have all of the options available to us.

Terri

[littleone1]

Corky has an appointment with his vet tomorrow morning, as the discoloration is getting worse after two treatments. I would much rather that he went to his vet, who knows his medical history, instead of a dermatologist that I really don't have much faith in. He never even discussed Corky with me.

I know it has to be bothering Corky, as he is now rolling and crawling in the grass much more than he normally does. I used Relief Shampoo on him today. The poor little guy, as soon as I mentioned the word bath, he made a bee-line for the door.

Marie, thanks again for the links. I have a list of questions written down to ask the vet in the morning.

Terri

[mypuppy]

Oh no Terri,
Im sorry the treatment doesnt seem to be working and making it worse. geez. I hope you get some answers tomorrow. Do let us know how Corkys visit goes. hang in there. tight hugs. Xo

[Harley PoMMom]

I, too, am sorry the treatments don't seem to be working. :( Give Corky some hugs from Harley and me and I hope and pray that the vet can find him some relief.

Love and more hugs,
Lori

[frijole]

Thinking of you and Corkster and hoping tomorrow goes well for you. Kim

[AlisonandMia]

What sort of shampoo/wash was prescribed? Was it one containing an anti-fungal (like Malaseb (http://www.malaseb.net/)) because that is what you need to treat a yeast infection. It can be difficult as bathing (getting wet) actually makes the yeast happy so if the shampoo isn't pretty strongly anti-fungal it could actually make things worse!

Alison

[littleone1]

Thank you my friends for your thoughts, wishes and hugs. I hope I will be able to get answers tomorrow as to what I can do to help Corky.

Alison, the shampoo and the leave on lotion is KetoChlor. It is suppose to to be for the management of conditions responsive to ketoconazole or chlorhexidine and is suppose to reduce bacterial and yeast adhesions. Thank you for the information about the Malaseb and anti-fungals. I now have that on my list to ask the vet about.

I just want Corky to be able to enjoy his life without having all of his issues to deal with.

[AlisonandMia]

KetoChlor sounds like a good one - pretty much the same as Malaseb just a slightly different fungicide (Ketoconazole instead of Miconazole Nitrate I think).

Yeasts seem to be pretty resistant these days so can take a while to clear. Another good treatment is Lamisil (completely different chemical and there isn't so much resistance to it, yet). Don't know if it comes in a form that would be suitable for a dog for all over use though - you'd have to ask the vet about that. It does come as a spray on lotion thingy for feet I think which could work (could also sting and be unsuitable if alcohol based???). It can be expensive - but could be worth it.

[BestBuddy]

Buddy used Malseb for his flaky itchy skin but this was before the orange color started to happen. I had to bath him every two days for two weeks then weekly for another couple of months. He hated it and as soon as he heard the running water he found a place to hide.

I did notice the first few weeks that he seemed more itchy and flaky but I think it was the shampoo doing its job getting rid of the bad skin. I worry about these treatment for our dogs that say you should wear gloves to apply:( because if it too harsh for my hands then I really don't want to be putting it on my dog.

Jenny

[littleone1]

I added that to my list, Alison. Thank you. I don't care if it's expensive, if it is something that would help Corky.

When I used the Relief Shampoo today, it seemed to help him, at least from not itching, as it is oatmeal based. I'm wondering if he might be having an allergic reaction to the KetoChlor.

I've been going on different web sites to try to find as much information as I can.

I really appreciate your help.

[AlisonandMia]

Here's some info on Lamisil (terbinafine): http://en.wikipedia.org/wiki/Terbinafine

Don't let the list of possible side effects worry you unduly - I think side effects are far more likely when it is used as an oral medication.

Alison

[Franklin'sMum]

Hi Terri,

Just wanting to wish you and Corky good luck at the vets tomorrow and send you both big hugs :). Hope the derm vet can reduce Corky's itching.
Love,
Jane, Franklin and Bailey xxx

[littleone1]

We just got back from Corky's vet. Corky has both bacteria and yeasts infections in both of his ears. He definitely has a yeast infection.

He will be continuing to use the KetoChlor, as his vet doesn't think that Corky had an allergic reaction to it. I'm to use it 2-3 times a week, leave it on for twenty minutes, rinse it off, and then put Comfort Conditioner on the affected areas. I have to use an anti-fungal ear cleaner and Otomax twice daily for 14 days. He will be taking Simplicef-Cefpodoxime, an antibiotic, and Fluconazole for the yeast infection. His vet made sure that these can be taken with cushpups who are taking Trilostane.

I asked him about the Malaseb and the Lamisil, Alison. He said the Malaseb and KetoChlor were about the same. The Lamisil is used to treat a different kind of fungus from what Corky has.

Thank God for Corky's regular vet who really knows him. I feel so much better now.

Thank you all for your well wishes. They really helped.

[Harley PoMMom]

Poor Corky! :( He's got yeast coming out of his ears, literally! :eek: Sending tons of healing energy your way for a speedy recovery for our Corky. Give sweet Corky some gentle hugs from his Auntie Lori and tell him that Harley and I hope that he is feeling better real soon.

Love and hugs,
Lori

[sunimist]

Poor baby! Love and (((hugs))) to you both. Praying for relief and improvement real soon for the little guy.

Shelba and Suni~~

[littleone1]

Thank you my dear friend for the healing energy.

Corky wants me to thank his Auntie Lori for the gentle hugs and you and Harley for hoping he feels better soon.

My poor little Corkster. I think he could probably dislike me very much right now for all of the things I've been putting him through, but he is so loving and forgiving.

I did find out from Corky's vet that his liver could have been secreting a substance which could have caused the discoloration in his nails, even if his liver enzymes weren't elevated. He told me that this does happen to birds and some other animals.

[littleone1]

Thank you Shelba for the love, hugs and prayers. They are greatly appreciated. Corky is a tough little guy, and I know everything will be better soon.

[spiritdog6]

I have been in my own whirlwind of "dog gone bad", but I did want to wish Corkster a speedy recovery, and less worry for you.

[littleone1]

Thank you so much Spiritdog6. The Corkster and I really appreciate it.

I totally understand that we can get into whirlwinds with our furbabies, but we do have a very wonderful group here who help us to get through it.

Terri

[Squirt's Mom]

Hey Terri,

Have you considered buttermilk or yogurt for Corky's yeast? They both have natural cultures that combat yeast. If he can tolerate the lactose, it might be worth a try along with the meds. Just wool-gathering again...:p

Hugs to both of you!
Leslie and the girls - always

[littleone1]

Hi Leslie,

Thank you for this information. Corky use to have fat free cottage cheese and plain low fat yogurt as part of his diet a while back. He's never had any problems with dairy products. He still gets some of his meds with light mayo, as this is the only way I can get him to take them when they are not being taken with his meals. I will get some yogurt for him when I go to shopping.

[Squirt's Mom]

Hope it helps. Several times when I have been on antibiotics I have had to use buttermilk or yogurt to counteract the yeast the ABs caused. Can't stand either one but they did work!

Hugs!

[SasAndYunah]

Hi Terri and Corky,

We're so sorry to read about the yeast plaguing Corky :( But I couldn't agree more with Leslie about the yoghurt/buttermilk. It wouldn't hurt either to keep Corky on it, also after the yeast has gone since it also works preventative and it's very good for an intestinal balance :) I always add a tablespoon of yoghurt to Yunah's diet :)

And perhaps, to make the bathing a bit more comfortable/pleasurable to Corky, you could give him some (T-Touch) massages during the 20 minute soaking period....I'm pretty sure he'll love it :p He might even start to love bathingtime, looking forward to his massages :D Do you know some of the T-Touch techniques? If not, there are plenty of books that have detailed drawings and explanaitions...but I also could forward you some by mail if you wish?

Give Corky a big hug from us here and all our best to you,

Sas and Yunah :)

[littleone1]

That's a good idea Leslie. It's easy to give him the yogurt mixed in with his chicken and rice.

[littleone1]

Thanks Sas,

Since he is not able to fight off things like he use to, I will keep the yogurt as part of his diet.

I never heard of the T-Touch massages before, but I am definitely going to look into them.

Luckily, Corky won't have to be in the tub. With the KetoChlor leave on lotion, I just need to wet the areas being treated. It gets massaged in. When I have to rinse it off, I have a washbasin that I can take outside, since it's so hot here, and I keep using a wet washcloth until it's rinsed off.

Corky thanks you for the hugs, and thank you for your wishes. Give Yunah a big hug from me.

Take care.

[SasAndYunah]

Hi Terri.

here's a link about T-Touch if you are interested. I did a T-Touch seminar and use it lots! :D When I had Panda (the Turkish stray I fostered last year) I used it very often for several reasons and occassions. To make him more selfassured but also in the waiting room of the vets office to calm and relax him. It works wonders :) And I use it with Yunah just for fun, relaxation and bonding purposses...:)

Hugs,

Sas and Yunah :)

http://www.lindatellingtonjones.com/howtodoTTouch.shtml

[littleone1]

Hi Sas,

Thank you. I just watched the short video on it. I'm going to try this on Corky when we have storms, and when he has to see his vet and his IMS. He gets so scared anymore. He shakes and pants terribly.

I will let you know how it works, as we're suppose to have another storm tonight.

Thanks again.

[SasAndYunah]

And here's a link to an example to 4 kinds of Touches:

http://www.ttouch.com/examplesTTouch.shtml

I'll go through my T-Touch book and see what kind of touches would be used for fear of thunder/storms/loud noises... I'll let you know what I have come up with for Corky...and you :D

Sas and Yunah :)

[littleone1]

This is so great. I really appreciate it Sas.:)

[SasAndYunah]

Okay, here's one specifically for letting go of fear - acute, chronic or longstanding fear...the Tail Touch. With Corky's short tail I would use the Raccoon Touch (was in the example list in the link above) on the tail. And you can also circle the tail in both directions, that will release both physical and emotional stress. Use one hand to stabilize Corky and (if possible with the docked tail, depends how short it is) lift the tail near the base and move it around in a circle, go both directions.

There are more but I need to make sure I explain them to you in the right way so you understand how to do them. But for today, do the tail (Raccoon Touches) and if possible the circling of the tail and some general T-Touches over his body (the one and a quarter circles) :)

Sas and Yunah :)

[SasAndYunah]

Okay, and then there's the Ear Touch. A stroking or circular TTouch on the ear. This stimulates the accupressure points on the ear and has a positive effect on the whole body...

And the Mouth Touch. TTouches on and around the muzzle and on the lips and gums. The Mouth TTouch stimulates the limbic system in the brain, which controls the emotions. (Yunah loves this one :D )

Of course, if you notice that Corky doesn't like them, then leave it :) For example Yunah loves her muzzle and gums "TTouched, but not her lips, so I just don't do the lips.

Just experiment some, see what Corky likes and if nothing else, Corky had a great time being "massaged" by his mom ;) But these three (tail, mouth and ear) are especially used in case of fear for thunder/loud noises.

Have fun and hopefully just minor storms,

Sas and Yunah :)

[littleone1]

Thank you so much for taking the time to get this information for me. I will try all of them to see which ones Corky likes. It will be fun trying these and getting Corky to relax during storms instead of having to him give Melatonin. Sometimes it works, and sometimes it doesn't. I tried EFT, but that didn't work.

I already printed the information and bookmarked the links. :)

Give Yunah hugs from me.

[littleone1]

Corky's 3 month stim test had to be postponed because of the oral meds he's taking for his yeast infection. He has to be off of any oral meds for 7 days before he can have the test done. He won't be able to have it done until the end of the month. The infection is starting to get better. It is much lighter in color now. The bacteria and yeast infections in his ears are just about all cleared up.

Terri

[Roxee's Dad]

Hi Terri,
So glad to hear the Corkster is doing better and the meds are working :D

[Squirt's Mom]

Hey Terri,

I hope those nasty ole bugs and yeasties are gone for good real soon!

Hugs to you and belly rubs to Corky,
Leslie and the girls - always

[littleone1]

Thanks John and Leslie.

I'm glad they're working. I know his ears will be okay. I'm hoping that when he finishes the treatments and the oral meds that the other yeast infection will also be gone. He still has well over a week to take them.

Give both of your furbabies hugs and belly rubs from me.

[mypuppy]

Hi my dear friend,
Glad to hear our little guy's improving a bit, and I bet he would be thrilled to know he has an extra couple of weeks before his next dreaded stim, even though we know how important they are and our most reliable source aside from the babies themselves. it has been quite crazy with personal issues and why I have not been very available. I am hoping to wrap up some things this week and hopefully we can try to communicate some time next week. thinking of you and Corky always and sending all our love. Xo

[littleone1]

Hi to you my dear friend,

I'm sure you've been busy, especially with the girls being home and everything else that happens.

Our little Corkster is doing better. Thank God he only has 3 more days with the ear meds. I feel so bad for him. As soon as he sees the two bottles, his ears go back and his head goes down. His ears have really cleared up. He's been fine with the topical and oral meds, which he still needs to be on.

I hope Princess is still doing good. Give her a big hug and belly rubs from me.

Corky and I luv ya bunches.

[addy]

Hi,

Glad to here Corkster is "getting the red out" ( I think I borrowed that from an eye drop commercial) and feeling better. It is always something, isn't it?

Let me know how the T Touch goes. I was at a dog fair last year and
watched a dog getting a T Touch Massage. Boy, he sure looked happy!!!!

Zoe is afraid of thunderstorms too. So far the melatonin seems to help a bit.

Thanks for the advice the other day:)

Addy

[littleone1]

Thank you Addy and you are very welcome. You are so right. There is always something going on with our precious furbabies. They definitely keep us going.

Corky really likes the TTouch massages. The other night we had storms around us and Corky started shaking and panting. I took him back to the bedroom and used the TTouch massages on his body and ears. He calmed down after a few minutes. He really likes those. He doesn't like the ones on his lips or gums. I feel better about using these than I do with giving him Melatonin. Before he was diagnosed with Cushings, I was giving him Acepromazine, which is a no-no now.

Take care.

Terri

[littleone1]

Corky's ear infections have cleared up, but his other yeast infection is still there. It's not as bad as it was. He's probably going to have to go back on the oral meds, but I have to wait until he has his stim test done. He's starting to show signs that his cortisol level is on the rise. He's going to have the test done on Tuesday. Once that's done, he'll be going back to his vet so we can figure out what's going on with the yeast infection. I started using an elimination diet to see if it might be food related. I know this takes time. Hopefully it will go away soon.

[addy]

Wishing you good luck on the stim test. I read yeast can be hard to get rid of and that grain feeds yeast so maybe a new diet could help.

Zoe had stains on her paws from holding her Kong, I thought it was mineral spit and worried it was yeast. Once I stopped her armour thyroid supplement, it went away. Not sure why a glandular product would do that but it did.

Have a great weekend!!!!

Addy

[Franklin'sMum]

Woo Hoo Terri and Corky!!! :):):)
So glad to hear that Corky's ears have cleared up :D:D:D. Don't they just hate the ear liquids?? With any luck, the buttermilk/yoghurt will keep those nasties away. Hoping Corky's stim test goes well, and that his other yeast infection will clear up very soon.
Hugs to you Terri, and belly rubs to our sweet boy :)
Jane, Franklin and Bailey xxx

[apollo6]

Glad to hear Corky's ear infection is better. I have to once a week clean out Apollo's ear from brown stuff.
Good luck on the stim test. WE are cheering for you.
Love Sonja and Apollo

[littleone1]

Thank you for your wishes Sonja, Jane and Addy.

I was doing research on yeast infections, and read that they can take weeks or even months to clear up. Hopefully, it will be sooner than later. I'll keep trying to pinpoint what caused it.

Give Apollo, Franklin, Bailey, and Zoe belly rubs from me.

[frijole]

Well its mostly good news! Fingers crossed on the test. Hugs, Kim

[littleone1]

Thanks, Kim. We're getting there slowly but surely. I'll definitely take one problem solved at a time.

[littleone1]

I'm doing the waiting game again. Corky was finally able to have his stim test done yesterday, but I still didn't get the results. He also had a full blood chemistry panel done along with checking to see if he has another UTI. Another T4 test was also done. His yeast infection still has not cleared up, and based on the results of his tests, he might still have to go back on the oral meds. :(

Terri

[frijole]

So sorry Terri.. waiting for results is the hardest part... and the worry. I've got everything crossed in hopes of great results. Hugs, Kim

[littleone1]

Thank you, Kim.

I know I've been a little pre-occupied with Corky and what's been going on with him.

I hope that Annie is doing better.

[Harley PoMMom]

Hi Terri,

Me and my gang have everything crossed for great results on all tests too. Give sweet Corky some hugs and kisses from Harley and me.

Love and hugs,
Lori

[frijole]

I know I've been a little pre-occupied with Corky and what's been going on with him.



That's your "job" as mom - to worry. Hang in there and keep the faith. Corky is lucky. Hugs

[Marlene]

Terri,
I hope, hope that Corky has good results from the blood tests. I will be checking and keeping my fingers and toes crossed, too!!:):)
Love and hugs from Marlene and Lacey

[mypuppy]

That's goes double for us my dear friend and Corky.

Luv ya. Xo

[Squirt's Mom]

And triple for us, honey!

Hugs,
Leslie and the girls - always

[littleone1]

Thank you everyone for your good wishes and hugs and kisses.

Unfortunately, I just got Corky's test results, and his cortisol level is up as I suspected. The signs were there. The last time his post stim was 5.3. This time it is up to 7.4. He is now going to be taking 40mg of Trilo with twice a day dosing. He will be taking 20mg in the A.M. and 20 in the P.M. He has to go back for his next stim in 30 days.

The only other results that were high were the BUN which was 48 with a reference range of 6-31 mg/dl and the BUN/Creatinine Ratio which was 60, with a ref. range of 4-27. All of his other test results were in the normal range.

Corky has to see his vet tomorrow afternoon about his yeast infection. He most likely is going to have to take the oral meds again. He will be totally freaked out.

[SasAndYunah]

Hi Terri,

I am sorry to read that the results were up :( But hopefully, when Corky's Cushings is better controlled, it will be easier for him to overcome the yeast infection. And....think TTouch tomorrow, it may help Corky with the vet visit :)

All our best and hugs,

Sas and Yunah :)

[littleone1]

Thank you Sas.

I did use TTouch on Corky when he went for his blood work. It did help calm him down. When we went back for the second blood draw, he was much calmer. Thank you so much for sending me the info on TTouch.

Big hugs and lots of belly rubs for Yunah.

[apollo6]

I am so sorry to hear about Corky. Will be praying for you

[Squirt's Mom]

Hi Terri,

Well, I wish you had been wrong and his numbers were still good but you know your baby!

I hope the increase will help bring him back in line and his signs will go away again.

Keeping you in my thoughts and prayers,
Hugs,
Leslie and the girls - always

[addy]

Hi Teri,

Hopefully the dose bump will help and that will also get the infection under control.

Give the Corkster a big hug from me and Zoe.

Glad the T Touch helps.:)

Hugs,
Addy

[littleone1]

We're back from the vet. There was no evidence of any infection on his skin like there was before. His vet said that's it's probably the pigmentation of his white fur at this time. He wants me to keep using the KetoChlor twice a week. He also said that I could still give Corky rice, but no breads or anything with wheat. He will be staying on a high protein diet.

I love the great communication between my IMS and vet. They always fax the information about Corky to each other.


Thank you Sonja, Leslie and Addy. Corkster thanks you for the hugs. Thank you for keeping us in your thoughts and prayers.

[Franklin'sMum]

Hi Terri,

I'm sorry Corky's results weren't better :(. Hoping the twice daily dosing does the trick for him. If you're concerned about the BUN and BUN/Creatinine ratio, (being the worry-wort you are ;)) they can rise with a high protein diet. It's great that your vet and IMS keep in constant communication though :)
Love to you and Corky,
Jane, Franklin and Bailey xxx

[littleone1]

Thanks Jane.

I'm hoping the increased dosage and continuing the twice daily dosing will help Corky's cortisol level. He does seem to have improved a little after being on this dosage for 2 days now.

You're right!:) I was a little concerned about the BUN and BUN/Creatinine ratio, so I also asked my vet about it yesterday. He didn't feel that it was anything to worry about. He also told me that since Corky ate that this would cause these levels to be increased.

Take care.

(((HUGS))) for all of you.

[Harley PoMMom]

Hi Terri,

While searching omega 3 fatty acids I came across this article and thought I'd share a quote from it:
Yeast Infections: Fatty acids have been shown to slow down the growth of Malassezia pachydermatis, a common yeast infection in dogs and cats, in the laboratory. It is thought, these fatty acids may play a beneficial role in the treatment of this yeast infection on the skin and ears in dogs and cats. http://www.peteducation.com/article.cfm?c=2&aid=666

Don't know if this will help our sweet Corky or not...then maybe you are already giving him the omega 3??? Give Corky some hugs and kisses from Harley and me and big hugs to you too!

Love and more hugs,
Lori

[littleone1]

Hi Lori,

Thank you for this information my dear friend. I read the article. Corky gets Omega 3 and 6 fatty acids in his Science Diet treats for the skin and coat. The comfort conditioner I have to use after I put the KetoChlor has Omega 6, and the TRA + Keto that I now have to use to clean his ears twice a week is for antifungal and antibacterial use.

I'll look into other ways of getting more Omega 3 in him. I'll check with his IMS and his vet to see if they might suggest specific things that I can use with Corky.

It's back to the rollercoaster ride!:(

Corky and I thank you and Harley for the big hugs and kisses. We're sending them right back to you, Harley and Bear.

As always.

[Franklin'sMum]

i'm hoping the increased dosage and continuing the twice daily dosing will help corky's cortisol level. He does seem to have improved a little after being on this dosage for 2 days now.

YAY!!! Woo Hoo! :)

[mypuppy]

Hi there dear friend,
Sorry to hear Corkys levels were elevated but glad you have seen a little improvement in just 2 days. I hope the stubborn yeast infection clears up soon for him. Ugh. Hang in there and always thinking of you and the Corkster with love. Tight hugs. Xo

[littleone1]

Thank you my dear friends, Jeanette and Jane.

I just put a new picture of Corky's fur discoloration in his album. I feel so sorry for my little boy.

As always,

[Marlene]

I hope you and Corky are doing OK and Corky is doing better with his new dosage. I saw the pictures of Corky's coat. Lacey is getting the same pattern. Lacey has been having skin problems the last two weeks, too, so I took her to the dermatologist at CU today. She said it is a proliferation of mites!!! They are normally there, and on all people,too, eewwww, but when the immune system is compromised with Cushing's they really multiply and start causing problems. She has prescribed Interceptor on a daily basis to get them under control. She said starting the Trilostane will also help keep them in check. As a precaution, she is checking to make sure it does not interact with Trilostane. The pharmacist is supposed to give me a call to tell me if it is OK to use it with Trilostane. The vet said she is pretty sure it won't be a problem. I hope not.
Does Corky scratch at the patches? Do you have any suggestions for something that eases the itching and burning of skin problems? I was using a product from PetMart, but it is gooey and icky. Someone had mentioned oatmeal baths. I thought I would give that a try. Have you tried anything that seems to work? Lacey used to be all snowy white. She has a lot of staining now. I agree with you that it is sad. Her whole face is brown from the eyes tearing up and the medicine. :( I'm afraid to use the stain removing product because I don't want to get anything in her eyes to irritate them more.
Hope you and Corky are having a good day!
Hugs from,
Marlene and Lacey

[littleone1]

Hi Marlene,

Both the dermatologist and Corky's vet did a scraping and a culture, and both of them said it was due to a yeast infection. Neither one of them mentioned mites. When he was to the vet last Friday, the yeast infection was gone, but the discoloration started getting worse again. I really believe that Corky is having an allergic reaction to the KetoChlor. When I first started using it, the discoloration seemed to spread. When I used it on Corky Tuesday, the same thing happened. I called the company and spoke to a tech there. She was going to give their vets all of the information. I'm not going to use it anymore. If I don't see any improvement by Monday, I'll be taking Corky to the vet. Corky never had anything like this before.

Corky hasn't been scratching. It doesn't seem to bother him. I've been using Comfort Conditioner on him, which his vet suggested to use after I rinsed off the KetoChlor. You wet the fur and leave it on for 5-10 minutes and then rinse it off. It's an anti-itch conditioner with Omega-6 Fatty Acids and Oatmeal. A few years ago I use to use Relief Shampoo which contained the same ingredients.

Corky and I are doing good. He's actually been leaving some of his morning meal on his plate. The last two nights he slept all night.

I hope Lacey's condition improves. I know they don't understand what's happening to them. Did the dermatologist give you anything else to use? Keeping everything crossed that it clears up soon.

Have a good rest of the day. Give Lacey hugs and belly rubs from me.

[Squirt's Mom]

Hey Terri,


He's actually been leaving some of his morning meal on his plate. The last two nights he slept all night.

This sounds like improvement to me! :) Does he seem to be feeling good? I bet you both enjoyed a full nite's rest or two and I hope it continues!

Are you sure that after his baths Corky isn't dropping and dragging across something that leaves a dye behind? :p;) I had a dog that would do that - drop her chest on the floor with her front legs out behind her and push herself across the carpet for a bit after every bath! It was funny to watch! :D

Hope things continue to improve for Corky!
Hugs,
Leslie and the girls :D - always

[sunimist]

This may be a stupid thing to say, but gonna say it anyway. :) Suni had terrible tear stains causing horrible yeast discoloration around her eyes and even spread up toward the front of her head. Some poodle folks told me to use Angel's Eyes and it has worked perfectly for her. She still has some tears, but no more yeast discoloration. So I was just wondering if it might be effective for other areas of the skin.
I may be way off in left field, but just had a light bulb moment. :o

[littleone1]

Thanks, Leslie.

Corky feels good. It was cooler here this morning, and he took off running during our morning walk. He went like a bat out of h_ _ _ !:D
He walked for an hour and 10 minutes.

The KetoChlor I am using on him is the stay on lotion, which gets rinsed off after 20 minutes. The white fur on the back of his neck has not changed colors. The discoloration is only where I was putting the KetoChlor. He doesn't rub his underside on anything while it's on, as I will do something in the kitchen for that time period, and he stands between the family room and kitchen watching me. It's another waiting game to see what happens.

[littleone1]

Hi Shelba,

I don't think this is off the wall, as Corky had the tear stains a while back, and I was told that I could use Angels' Eyes, but it wasn't really necessary, as the tear staining was only cosmetic. Since the Angels' Eyes is put in food, it could very possibly help. Thank you. I didn't even think about this until you mentioned it.

P.S. I just looked up some information on the web, and it is also used for pet coat stains.

[sunimist]

Well, there you go! Might be worth a try. It's a bit pricey, but well worth it I think.

[Sabre's Mum]

Hi Terri

I see that KetoChlor is a shampoo containinc Chlorhexidine. When Sabre had his skin issues we used a shampoo called Pyophex - it contains Chlorhexidine. The vet warned us that some dogs could not tolerate it and Sabre was one of those. It made his skin issue more reddened and it appeared to irritate him .... can't comment on the hair colour change as he was ..... "russet gold"!!! We changed to an oatmeal based shampoo which worked much better - not sure whether you can get it in the US it was Aloveen.

Angela and Flynn

[littleone1]

Thank you Shelba and Angela.

I don't care what it costs, as long as I know there is something that can help Corky.

I'll do some checking to see if I can find the Aloveen here in the states.

Thank you both for the information.

[sunimist]

Terri, when you have time, go look at the latest pictures I just put up of Suni and notice that her face is as it should be now. I kid you not, it was awful before and I was worried to death about her.

[Harley PoMMom]

Tylosin is what is in Angel Eyes and this you can get compounded thru Diamondback Pharm. as I did this for Harley. Check pricing with Diamondback first because they may be cheaper. :)

Love and hugs,
Lori

[addy]

Hi Terri,

The Angel Eyes has tylan in it which is what I believe helps the staining. My Koko has the eye staining too and I have been told to ignore it but sometimes that is hard to do. :(

I guess if the staining was caused by yeast then I could see why the tylan would help, right? At least seems likely to me, what do you think? But then, could you just buy tylan? I guess we would not know the dose if we did that. Can you tell I am thinking out loud?:o

Hoping Corkster runs circle around you tomorrow:D:D

Hugs,
Addy

[littleone1]

There is a big difference. I just got off of the phone with the vet and they don't recommend it, but Corky's IMS said I could use it. I'm going to try it.

[littleone1]

Thanks Lori and Addy.

I will give Diamondback a call, as I do have to get a refill on Corky's 20mg capsules.

I need this ride to stop for awhile!

[BestBuddy]

Just some comments on the red staining.

Luke is quite white all over except for the red/brown stripes that run down his face from his eyes.

I didn't want anything harsh so I am trialing Optrex which is a human eyewash. About 3 weeks ago I trimmed all the colored hair from Luke's face and I have been wiping the area with a cotton ball soaked with Optrex. I did it 3 times a day for the first week and then twice and now I am doing it once a day. I have to say the area looks so much better and I think it is working.

Because the Optrex is meant to go in the eyes I am not concerned that it will cause any problems. I guess it would be available in the US and maybe it would be something to consider for any areas of the coat. I got a 110ml bottle for around $10 AUD and in three weeks or so it is still half full.

Jenny

[littleone1]

Thanks for the information, Jenny. I'll check my local pharmicies to see if they have it.

Lori, I just got off of the the phone with Diamondback, and I can actually get the Angels' Eyes at a lower price from another website instead of getting the Tylosin compounded. They were great. They did alot of research for me.

[frijole]

Did you buy it yet?!!! We sell Tylan where I work and I have 1000 empty capsules and most of a container in my shelf!!! It is the SAME thing as Pretty Eyes. PM me if you want mine! Free to good home :D

[littleone1]

Thank you Kim. Bless your heart. I'll PM you.

[mypuppy]

Oh Terri,
I wish I had something valuable to say to help Corky. So sorry he's still fighting this stubborn infection. Iwillbe saying my prayers tonight for some healing. I know he will answer them. I miss ya dearly and love ya both bunches. Xo

[gpgscott]

Hi Terri,

Sorry I have nothing to add but I was looking in tonight and wanted to wish you both well.

Scott

[littleone1]

Thank you for your prayers my very dear friend.

I know Corky will overcome this, as he's overcome so much in his life.

We luv ya and miss you bunches, also.

Hugs and belly rubs for Princess. (((((HUGS))))) for you.

[littleone1]

Thank you, Scott. I appreciate your well wishes.

Terri and Corkster

[Casey's Mom]

Hi Terri - just a thought about the tear staining. My cream coloured Havanese Desi gets tear staining and was I was about to try Angel Eyes when a groomer told me wheat causes the staining. I checked her food and there is no wheat listed but it was in her Old Mother Hubbard cookies that she gets as a treat. I have since changed her treats to wheat free cookies and no more tear staining!!

Best luck to you and the Corkster,

Love and hugs,

[littleone1]

Thanks, Ellen.

I'm not concerned with the tear staining as much as I am with the fur discoloration. I haven't been giving him anything that has wheat in it since his vet told me not to. There has to be some underlying problem that hasn't been brought to the surface yet. I'm hoping that the Tylan will help him.

I have a strong feeling that Corky had an allergic reaction to the KetoChlor and might have to take Prednisone for it, which would really play havoc with his cortisol level. He had to take Pred several years ago when he had mastacatory muscle myositis. After he was weened off of it, his allergies really acted up, and he had to be put back on it. I'm hoping it might just be a matter of giving him his allergy meds.

I'm exploring every avenue that I possibly can.

[addy]

Hi Terri,

A few months back I was speaking with the owner of our holistic pet store. She had her pup on Angel Eyes for quite a while and noticed a change in the color of her pup's fur. She had honey colored spots and off white fur and the fur started to bleach out its color. She thought perhaps it was just her pup getting older but when she stopped the Angel Eyes she noticed the fur's color starting to come back. Last time I saw her baby, her color was fine.

Now I can't say for sure it was the tylan but thought I would mention what she thought had happened. Her pup has allergies too.

I am really hoping the Tylan helps Corkster. Prednisone would not be a good thing:(

Addy

[apollo6]

twice daily
as quoted by manufacturer
27. Twice daily means increase dosage by 1/3 or ½ only > Which would be 10 +5=15mg divide in two, would be 7.5 mg in morning and 7.5 mg in evening(18hr difference) Dr. Allen said I could do 10mg in morning and 5mg. in evening (compounded) because Apollo is so little would not want to go any higher.

I use Ark natural
http://www.amazon.com/Ark-Naturals-Bright-4-Ounce-Bottle/dp/B00014TQWI/ref=sr_1_1?ie=UTF8&s=home-garden&qid=1284321538&sr=8-1

but I don't know if this for stains.
Apollo is going up to 12.5 mg. because he has had good results , but like Corky his readings are starting to go up just a little, still good range, but the gait is very stiff, hope the minor increase will help the muscle weakness.
Hope this helps.
hugs from Sonja and Apollo

[littleone1]

Hi Addy,

Thank you for this information. Corky's fur is starting to get darker again. He's due for another stim test in 2 weeks. If he would have to go back on the oral meds, he would have to be on them for 3 weeks and then couldn't have the stim test done for 7 days after he was off of the oral meds. Since he's on a higher dosage now, I am really inclined to have the test done first before I take him back to the vet. Being on the 40mg vs the 31mg for another 6 weeks has me a little concerned.

I'm going to try the Tylan to see if it helps.

Terri

[littleone1]

Thanks Sonja, and thanks for the link.

When Corky's dosage was increased from 25-31mg, his IMS said that we could do it in twice daily dosing instead of once a day. Because I had so many 20mg capsules left, Corky was taking 20mg in the morning and 11mg in the evening. He was taking them 12 hours apart. Now he's getting 20 and 20.

I hope Apollo's muscle weakness improves. Corky's legs get stiff when he's resting. He'll walk a little slower at first, but once he starts moving, he goes very fast. His stiffness is due to his arthritis.

[addy]

It sounds like a good plan to me!:)


FYI, I was on the Angel Eyes website looking at their photos and the site had a photo of a white dog with half it's body discolored, the after photo should no discoloration at all. It also talks about the yeast and bacterial infections, etc, did you check out the photos? I think they are real.

Zoe had the staining on paws, mouth and a little around the eyes but it went away after I took her off the thyroid natural supplement or so I thought. Now I wonder if it went away because the metronidazole she was on for a month got rid of the yeast:confused:

Hugs,
Addy

[littleone1]

Thanks, Addy.

I haven't checked their website. I'll check it now.

I just looked at alot of the pictures and the discolorations are about the same color as most of Corky's white fur. Unbelievable!

[Franklin'sMum]

Hi Terri,
Just looking in and sending you and Corky healing thougts. I really hope you get some answers soon.
Jane, Franklin and Bailey xxx

[littleone1]

Thank you so much for checking on us and for the healing thoughts, Jane. I'll definitely keep you posted on what happens.

Hugs and belly rubs for Franklin and Bailey.

[frijole]

I'm checking in too! Did the package arrive? Sending best wishes. xoxo, Kim and Annie

[littleone1]

Thank you Kim for checking on us.

The package didn't arrive yet, but I'm sure it will be here shortly. I have to find my UPS account information to check the tracking no. I have so many user accounts and passwords that I can't remember anymore unless I write them down.:D Another senior moment!:D

I hope Annie is doing better. Please give her a bunch of hugs , belly rubs, and ear scratches from me.

Thank you so very much. (((HUGS)))

[apollo6]

Sorry haven't checked in with you lately.
Hope you and the Corkster are doing better.
Hugs Sonja and Apollo

[littleone1]

Thank you for checking on us, Sonja. Corky has been taking the Tylan for 3 days now, and it looks like there might be a little of his white fur returning. I'm going to stop giving it to him on Monday, as he has to have his stim done next Tuesday. Once he has that, I'll start giving it to him again. I don't want his stim or blood tests results to be skewed if he's taking the Tylan.

I hope Apollo is doing better.

[apollo6]

Dear Terri
Know what you mean. Hope the little guy gets better.
Still dealing with the hind leg weakness. I just wonder is it the Trilostane, arthritis, or degenerate joint disease. IMO want me to go from 10mg to 12.5mg compounded. Need the courage to do.
Hugs Sonja and Apollo

[frijole]

Terry, I did quite a bit of reading on the tylan and those using it for stain purposes said it is the NEW hair that comes in stain free so it takes a while to see a total change. They also said once the dog is taken off of tylan the staining returns. Alot of them leave their dogs on it permanently at a very low dose for this reason.

[littleone1]

Thanks for this information, Kim. Once Corky has his stim and blood work done next week, I'll start giving him the Tylan again. I know that when he had his last stim done, he had to be off of the oral meds for 7 days before he could have it done. I still gave him the Tylan today.

Thank you so much for your help. I really do appreciate it.

[apollo6]

Hope things improve.
Hugs Sonja and Apollo

[addy]

Hi Teri,

Hope Corky is doing well on the Tylan. I bought a giant bottle of Angel Eyes for my Koko:) I couldn't figure out how much I would need so hubby said "get the big one". OMG you should see the size of that bottle!!!! We'll compare notes after Corkster's stim.:)

Hoping everything goes well with the stim. I'll be thinking of you both.

Paws and fingers crossed
Addy

[littleone1]

Hi Addy,

I thank you both so much.

It's been a little hectic the last few days, and I'm trying to catch up on the threads. I'll try to read your thread in a little while. I hope things are improving.

I haven't given Corky the Tylan since Monday, as he has his stim test on Tuesday. He will be getting the U/S done this time along with the full blood chem panel that I always have done when he has his stim test. Once he has his stim, I will be putting him back on the Tylan. I actually think I'm seeing a little of his white fur returning.

I hope the Angel's Eyes help. The bottle of Tylan is also quite large.

Take care.

[apollo6]

Hard to keep up with each other.
Apollo goes for his next STIM test next week. When does it end.:eek:

[littleone1]

It is hard to keep up on everything. I know there are new threads that I haven't read yet.

I hope you get good results on Apollo's stim.