Help Pug 6 Years UCCR Test [Archive] - Canine Cushing's Information and Support Forums

tpirovol

12-07-2011, 06:23 PM

Hi Everyone

My name is Terry and I live in Toronto Canada. My 6 year old Pug Boo has suffered for years with allergies, Arthritis and on/off skin infections. We originally thought it might have been diabities or thyroid but we did both test and they came back negative. She also suffered from ear infections and a blackened belly. About the same time as running these tests she suffered a UTI infection and during the xray for stones they found an enlarged liver. We decided to wait until the infections was gone for 3 weeks and go back to complete a UCCR. I brought Boo in last week but was not told that the sample should be taken from home and she had it removed from her bladder instead of collected from home. Boo's UCCR came back with a ratio of 23 from a baseline of 13. Our doctor feels that we should do a LDDST to rule out cushing disease.

I am hoping you can guide me as what to do next and how we can help out little Boo. I appreciate any advice you can give me and really really appreciate your time.

Below are my questions
1) Should we redo the UCCR with a sample from home
2) Is the LDDST better then the ACTH (I want to prevent the possibility of treating her for something she may not have)
3) If she is diagnosed with Cushings since she has allegies and Arthritis should we not treat her since I have read it might make her worse off.

--------------------
Timelines
1) October Boo suffered from a flea bit and had a huge staph infection. She was treated with Hexadine and Clavamox
2) November Boo suffered from UTI and was getting sick from a batch of food. She was placed on Batrel and her food was changed to The Honest Kitchen with Boiled Venison Shoulder (She eats better then I do). She also had an Xray to see if she had stones and was diagnosed with an enlarged liver
3) December Boo had the UCCR test with a ratio of 23 out of 13

Symptoms
1) Blackened Belly (This has gotten better since we changed her food)
2) Thinned Hear (Same better with the food)
3) Looks older (Mkght be becuase she is a pug)
4) Increased appitite (Might be a pug thing)
5) Decreased water intake (She has not touched water since her UTI. We feed her 1.5 cups of water with her food now)(she was getting very sick from her food and it was found that the food made many dogs sick and also killed some)
6) Uriniation (She uriniates about 6 times a day not sure if this is much more then normal)

Health Problems
1) Allergies to Chicken, Beef, Wheat, Milk and assuming dust mites
2) On and off staph infections
3) Calcification of the spin causing sever pain when walking
4) Arthritis of the front legs
5) Chronic ear infections

Here are the results from the UCCR
Her Levels = 23
Normal =<13

UASG = 1.022
Blood = +1
RBC = 21-50

Thank you everyone for your help. I almost cried when I heard she might have cushings.

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Harley PoMMom

12-07-2011, 07:41 PM

Hi Terry,

Welcome to you and Boo! I am sorry for the circumstances that brought you here but so very happy you found us.

Please know that Cushing's is NOT a death sentence, and when properly treated, dogs can live out their normal life spans.

Strong symptoms are a huge part of the Cushing diagnosis and a cushing's savvy vet will not initiate any treatment without strong symptoms and a confirmed diagnosis.

The UCCR test for Cushing's is useful only when the sample is taken at home because any kind of stress can cause the cortisol to elevate.

Not one test for Cushing's is 100% accurate and all Cushing tests can cause false positive results when a non-adrenal illness is present.

It would help us to provide you with more meaningful feedback if you could give us additional information about Boo such as getting copies of all test/s that were done and posting the abnormal levels here. Also how much does Boo weigh and is she taking any other herbs/supplements/medicines?

Please know we are here for you and Boo and will help in any way we can.

Love and hugs,
Lori

BestBuddy

12-07-2011, 07:45 PM

Hi Terry and welcome to you and Boo.

Lori is so right that cushings is not a death sentence. I know it is so scary when first considered but so many here are going or have gone through what you may be dealing with so there is a lot of support.

Jenny

labblab

12-07-2011, 08:01 PM

Welcome from me, as well!

Some of Boo's symptoms do correspond with a Cushing's diagnosis, but some things do not. As Lori has said, it can take some detective work to sort through symptoms and test results in order to arrive at a diagnosis that warrants treatment. And as you have already pointed out yourself, Boo suffers from some other conditions that may actually benefit from elevated levels of cortisol. So that makes a treatment decision even more complicated.

However, as far as your next step...I agree that I would start with a UCCR performed on a urine sample obtained at home. You really have nothing to lose, and it will be interesting to see if the second UCCR corresponds to the result of the first testing. As I understand it, you should catch a urine sample from the first pee in the morning. Further, a noted veterinary endocrinologist who was briefly a member here has suggested that the accuracy of the results can be increased if you pool urine samples taken on three successive mornings. I don't beiieve that is the "norm" among vets performing the test, but if you don't mind trying to get three samples, once again, you probably have nothing to lose.

If this second UCCR also is elevated, you may want to talk with your vet about proceeding first with the ACTH rather than the LDDS if your greater concern is falsely diagnosing Cushing's when it is not really present. The LDDS is more likely to give you a "false positive" in the face of other nonadrenal illnesses. Therefore, a "positive" on the ACTH is a more trustworthy indicator of the actual presence of Cushing's. The downside to the ACTH is that it is a lot more likely to miss making a Cushing's diagnosis ("false negative") in a dog that does have the disease, especially if the dog suffers from the adrenal form rather than the pituitary form.

Most importantly, Cushing's is a slowly progressing disease. So you have plenty of time to proceed with a thorough and accurate diagnosis. Once again, I'm really glad you have found us!

Marianne

tpirovol

12-07-2011, 08:37 PM

Hi Everyone,

Thank you so much for all of your replies an kind words. I was devastated when I was told cushings but I have faith with everyones help Boo and I will get through this. Boo is currenly 20pds and has rermainded within 2pds of this weight for the past couple of years. The main thing that has changed is her appetite but this has only happened in the last few months since we started feeding her THK and Venison. Her water intake is actually gone since switching her food and now we feed her with her food. I have only seen her drink water 2 times in the past 2 months. This is obviously bad but the Dr thinks she is getting enough water in her new food and is not thirsty since the food is not dry.

I have attached all of the test done in the past 3 months please let me know you thoughts. I think we are going to do the UCCR again and do the LDDS as well. This way we will know if it was the stress and ensure she does not have cushings and if she does we will just need to deal with it and ensure she has the best life possible. What are the side affects of doing the LDDS test if any? I want to do the UCCR test becuase I took her right from bed and put her in the car. She was shaking and scared and cried when they took her urine so that could be the reason of the high test results.

Currently she is eating the honest kitchen preference formula with the protien being cooked at home and it is vension shoulder. We give her, her food two times a day and a little more when she begs which is often.

http://postimage.org/image/cjwjxkv2x/
or
http://postimage.org/image/4gydm9ahl/

Please let me know your thoughts.
Thanks Terry

tpirovol

12-07-2011, 09:11 PM

Hi everyone sorry for my terrible grammar I was typing the last post from my Phone )

lulusmom

12-07-2011, 11:33 PM

Hi Terry and welcome to you and your precious Boo.

I just looked at Boo's bloodwork and urinalysis and cushing's is just not jumping out at me. The usual suspects on blood work, like high ALKP, ALT, Cholesterol, Triglycerides and a few others aren't there. The urinalysis looks like a dog with a UTI and I wouldn't trust the results of the UC:CR. As one of my favorite endocrine specialists says, "One would have to expect an abnormal UC:CR if a dog is already stressed at a vet's office and you roll them over on their back and stick a needle into their abdomen.

I believe that changing foods can change a dog's appetite. We switched my mom's dog to another food after a bout with pancreatitis and she loves it and has become a begger for the first time. Is it possible that Boo's increase in appetite is the result of her new diet?

With respect to the enlarged liver, was that observed on xray or an abdominal ultrasound? If they were looking for stones, I would think they would have done an ultrasound and if so, the adrenal glands should have been able to be seen. Was there any mention of the adrenal glands by your vet? The enlarged liver is common in cushing's but that enlargement is usually steroid induced and Boo's liver enzymes were normal so that doesn't add up either.

A dog with typical cushing's produces too much cortisol which is the body's natural anti-inflammatory. If an uncontrolled cushdog has arthritis or allergies, they are self medicating themselves. A lot of pet owners are surprised to learn that their dog has arthritis or allergies once the aches, pains and itchiness are unmasked once cushing's treatment reduces cortisol levels to a therapeutic level.

Aside from the allergies, which are at the top of the list of Pug health problems, and UTI's which are not exclusive to cushing's, do you know what your vet is seeing in the screening tests and physical symptoms that is driving him/her to pursue a cushing's diagnosis?

Glynda

Skye

12-08-2011, 12:07 AM

Hello Terri and Boo!!!!!
I adore pugs!!!!! i have been blessed in my life with being a pet parent to 3 in previous years.
On allergies.....have you tried to desensitize them? we did that for our pet son and he responded very well, also might ask if otc benendryl might be option? it would be 1 mg per pound...BUT dont give them if there are other meds involved be sure to check it out and make sure it is okay to give.
on the joints and muscles issues, i have heard and seen remarkable results with the adquin injections for dogs.
amazing diet your boo is on........Wonderful wonderful company and matter of fact i have a friend who knows the owner of the company and has toured the entire place.....amazing high quality feed. Good for Boo!!!! yeah!!!!! Your pet momma rocks! lol
on the liver.........did they ever figure out why it was enlarged? and how was that determined? by chance do you have a the CBC, biochemcial lab results?
My min pin just went through adrenal tumor surgery.....found by double cavity ultrasound........have you had one of these? In urine testing........does it indicate levels that would cause stones or abnormal amounts of crystals?
sorry for all the questions........you have found an amazing forum to be family with. The people here are truly angels, so if you here fluttering around you....no worries.....that is the angels from this forum. LOTS of knowledge here and lots of experiences. You will not walk this alone as you carry your boo to improved health.
love and paw hugs

tpirovol

12-08-2011, 12:47 AM

Hi Glynda & Skye,

Thank you both for your replies. I should have explained a little better that the first one is Boo's full Thyroid panel done around Aug/Sept. The second one is the CBC done around the same time. The third one is the UA when Boo had the urinary infection back in Nov. And the last one us the UA and UCCR done last week.

When my vet did the X-Ray they found the enlarged liver. There was no mention of any tumors just that an ultrasound should be done and further tests. The Xray was sent some where for a consult. He then recommend that once she got better we should do the UCCR and then go from there. Now that the UCCR came back high/grey area he is recommending we do the LDDS to find out if it is cushing or not. He does not think/believe it is but wants to do his due diligence especially now that the UCCR came back a bit high.

I think what got him believing she might be cushinoid is when Boo got a Flea bite a few months ago and had a huge staph infection. Her hair then started to thin due to the pyben shampoo. About a month after that she got the urinary tract infection which we believe was from a bad batch of food we use to feed her. She has had a lot of allergy and skin infections over the years.

Glynda: I also did a lot of research and did not see anything unusual with her blood and urine results that would indicate cushings. One question on her last test she had elevated RBC what could that be from.

http://postimage.org/image/cjwjxkv2x/
or
http://postimage.org/image/4gydm9ahl/

Do you think I should do the UCCR and LDDS? If I do go ahead with the LDDS besides the cost are there any concerns? Is the LDDS dangerous?

Again thank you for everyone replies Boo and I really appreciate it.

Harley PoMMom

12-08-2011, 01:33 AM

Do you think I should do the UCCR and LDDS? If I do go ahead with the LDDS besides the cost are there any concerns? Is the LDDS dangerous?

Neither the ACTH stimulation or the LDDS test are dangerous. With the LDDS test, plasma samples for cortisol are obtained before and 4 and 8 hours after I.V. administration of a low dose of dexamethasone.

If this were my furbaby, I would have an UC:CR redone after knowing that the UTI is completely gone.

Here are some links about the Cushing diagnostic tests: Selecting the Most Appropriate Test for Hyperadrenocorticism (http://www.vin.com/proceedings/Proceedings.plx?CID=WSAVA2007&Category=&PID=18195&O=Generic) and Diagnostic Testing for Hyperadrenocorticism (http://www.vin.com/proceedings/Proceedings.plx?CID=WSAVA2002&PID=2552)

Love and hugs,
Lori

tpirovol

12-08-2011, 02:24 AM

Hi Lori,

Thank you for your reply. I have done lots of research and some Dr like to use the ACTH first and others the LDDS. There is so much information out there I am in information overload. We believe her UTI is gone for over 3 weeks and the last UA shows no bacteria so I think we are good in that respect. The UCCR I will definitely redo and go with what tre DR recommends and do a LDDS as well.

Just wondering how much urine I need to collect for the UCCR? Can she eat or drink before collection? His do you normally collect urine from a dog? I was thinking of collecting the UCCR urine the day of the LDDS before I bring her in.

Last two questions has anyone had a dog with allergies actually gotten better after treating cushings? Boo has always had bad allergies and was hoping they might get better. When dogs are on cushings treatment do infections become less?

Again Thank you Terry and Boo

Skye

12-08-2011, 04:04 AM

i would def have ultra sound done. and maybe the acth test. along with the uccr test.
thing is....cushings.......or other issues that can be difficult to pin down.....these tests will sure help start leading you in the right direction.
Take notes of behavior, alert, eat, drink, energy, restless, interest, everything every detail you can of daily behavior.....see if you notice changes or least then you will have notes to reflect back on if changes occur.....watch for even increased shedding, etc.
amazing little details make us incredible advocates for our pet children.

tpirovol

12-08-2011, 10:21 AM

Hi Skye,

I think we will be re-doing the UCCR today or tomorrow. If that comes back high then I will recommend the ACTH and an ultrasound. As for the changes the only real change with Boo is that she does not want to drink water and loves her food way more. She always loved food and ever since we moved into our new home where the living room/kitchen are in the same room she begged for food more often.

Restlessness is about the same has not changed neither has her activity level which has always been LAZY :).

Just so I am clear if the UCCR comes back low then she most likely does not have cushings. Also how do you collect the urine sample from home?

Thank you again
Terry

Harley PoMMom

12-08-2011, 11:09 AM

Hi Skye,
Just so I am clear if the UCCR comes back low then she most likely does not have cushings. Also how do you collect the urine sample from home?

If the UC:CR results are under the normal limits for the lab you are using, which I believe is 13, then a Cushing's diagnosis is highly unlikely.

Collecting a free catch urine sample from a female dog is harder than a male dog but it is possible. One only needs a small amount of urine and I think some members have used aluminum pie plates/pans to catch urine. Since females squat so low to the ground to urinate the pie plate/pan can be slid under her while she is doing her business. Another suggestion is to use a pee pad which is flipped over and allowing her to urinate on the plastic side which then you can put the pee in a container. My vet gives me the pee containers and maybe your vet will too.

A dog need not be fasted and can have water for the UC:CR test and the first morning pee is recommended.

Hope this helps.

Love and hugs,
Lori

Skye

12-10-2011, 05:25 AM

i use plastic lids like from butter containers, sherbert containers, etc. right when i see them start to squat i slid the lid down and its in place before their even fully squatted, lol! its perfect size, some lids are deeper and smaller, they slide on ground quietly, fit between their quarters so they dont notice them so much. have never missed, knock on wood. :)

tpirovol

12-13-2011, 05:43 PM

Hi Everyone,

Just got back Boo's 2nd UCCR and to be honest I am disappointed and a bit sad! I thought for sure since the test was done in the office it would have been much higher. In the end the office test was 23 and the one at home was 22. The base line for the lab we sent it to is 13.

My Dr recommends the LDDS test and that is what we will be doing either tomorrow or Thursday. If our little Boo has Cushings I will not know what to do. She has sever arthritis of the legs and spinal calcification so she might be worse of with lower Creatine levels.

Does anyone have a dog that had arthritis before knowing about cushings? If so when you treated your dog did it get worse?

Also what is the most popular drug used currently for cushings. I was reading that some drugs destroy the glands and as such the levels stay low. My concern is if I do that and Boo's level drop and she is in pain that there is no going back.

Thank you everyone for your help.
Terry

tpirovol

12-14-2011, 12:50 AM

Hi Everyone,

Boo is going in for her LDDS test and I was just wondering if she needs to be fasted. Also during the 8hrs of the test is she allowed to eat or does she need to be fasted?

Thanks Terry

Moderator's Note: I have merged your latest post on Boo into Boo's original thread. We, normally, like to keep all posts on a pup in a single thread, so other members can refer back to the pup"s history, if needed.

Skye

12-14-2011, 03:15 AM

Terry
are they thinking adrenal gland cushings or pituitary?
drugs used are lysodren, trilo and Vetrol spelling is wrong on all those i am certain. sorry.
Adrenal tumor if not surgically removed can be treated with lysodren or trilostane
some think lysodren might be better if nearly 100% certain tumor is canersous. but it probably wouldnt help the tumor shrink any. and it takes higher doese to control cortisal. with trilostane its a good choice but works differently and no increase in dosage is needed but i dont know if it shrinks tumor either...i thought it did but i dont know. One is NOT easier on pet than the other though some think it is. When there are alot of different issues going on lysodren might be better because i think it helps with the over production of cortisol from OVER dosing. You would be surprised at how often you read of general vets and such perscribing dosages to high. Trilo make sure you get a hormone panel done. least then you got a base from where you started. then get a second panel done in couple of months to compare
all the medications are going to do is treat sypmtons.
Trilo blocks hormones so i think they just build up and not released
Lyso lowers cortisol, progtestorne and androstonedione and the 17 hydroxyprogesterone BUT not the hormone estradiol and i dont know why.
I think but again not certain that Trilo and Vetoryl are same but mfg in different countries from each other???? not sure.
Please make sure you vet starts on LOW LOW side of dosing. and a good source i believe i have in my notes is University of california at Davis and that will give different medication levels than Dechras which make the drugs that tend to always over dose animals. This is all from my notes that i have taken so please please please have cush angels confirm as i DO NOT want to mislead or guide you.
With Trilo ALWAYS ALWAYS ALWAYS have prednisone on hand in case dose is to much. DO NOT accept no for an answer if declined. GET SOME.
give trilo with food, its fast acting but short action where other takes longer and last longer.
example on dosing if my notes are correct trilo 20 pounds dose is according to Dechra is 20mg BUT UC Davis suggest 9.36 over half.
things to watch out for strange behavior like slow, not eating, fever, loose pooh, trembling.
as far as joint issues, have you looked into adquin injections.....i have heard remarkable things about them and my min pin is on desquinn chewable, (prescription) that work great as well.....she has back injury and slight back feet drag. you can hear it on carpet or concrete.
also have heard of water tread mills.
hope this helps. and sorry for all the misspellings. i am terrible at spelling.
So hopefully angels will be along soon and help more and verify or correct what i have given.
(((((((((((((((((((((hugs))))))))))))))))))))))))) ))

Squirt's Mom

12-14-2011, 09:38 AM

Hi Terry,

It isn't necessary to fast Boo for the LDDS. As for feeding between draws, you will need to talk to the vet about that. I am sure a treat would be just fine. ;)

Let us hear from you when it's over!
Hugs,
Leslie and the gang

tpirovol

12-14-2011, 11:52 AM

Hi Leslie and Skye,

Thank you so much for you info. They dont think Boo has either but since her liver is enlarged and she has had a lot of infections over the years they think she might. The only symptoms she has is hunger but I think that might be a Pug thing since she has always been hungry. She also does get infections easily and does look older then she really is. She also pee's maybe 5 times a day which is not that much I dont think. The last thing is that she has actually stopped drinking water since changing her food from dry to dehydrated. Now she gets 1.5cups of water with her food.

She just came back from the first LDDS blood sample and injection lets see what they say tomorrow.

Thanks Terry

addy

12-14-2011, 08:08 PM

Hi Terri,

A dog will drink less water when you take them off dry food.

Part of diagnosing Cushings is a pup having strong symptoms. The biggest part of the diagnostic tools is the pup's history since no one test is perfect and non adrenal illness can result in false positives.

I waited a year to treat my Zoe because her symptoms were not strong. Except for hair coat issues and hind leg weakness that was about it for a year.

Take your time and don't rush. Cushings is seldom an emergency.

hugs,
addy

tpirovol

12-15-2011, 05:38 PM

Hi Everyone,

I just got back news from the Dr that Boo does not have cushings. This is obviously good news but now brings more questions and more test to find the answers. Her test came back as below but she still has an elarged liver and will need to have an ultrasound and possibly biopsy of the liver.

One quesitons I had in regards to Boo's test is why did she have a high initial 0hr number? Also her level stayed low for the 4hr and 8hr I am assuming this is good can someone confirm.

http://postimage.org/image/ffvvko0nr/ ---Test Results---

Test Results
0hr = 98nmol/L
4hr = <27.7nmol/L
8hr = <27.7nmol/L

Normal: less than 40nmol/L
Hyperadrenocortisim: Greater than 40nmol/

I will be opening a site in the near future to help people with there dogs food allergies so keep an eye out at caninefoodallergies.com. Everyone's help her has been amazing. You honestly helped me more then any other forum I have ever belonged to and as a Server admin I have been a part of many.

I wish everyone on this forum health and happiness not just this year but in all of yours and your pets years! Merry Christmas and a Happy New Year

Thank you Terry

lulusmom

12-15-2011, 06:21 PM

Hi Terry,

Congratulations on the negative LDDS. The normal range you posted is for the blood that was drawn after the dexamethasone injection. The 0 hour number you are seeing is the cortisol level before the injection and you'll be happy to know that Boo's number is within the normal reference range. We're used to seeing things in ug/dl so if I did the math right, the range is something like 28 nmol to 166 nmol so it's all good!

I recently rescued a cute little Maltese mix male who has horrible skin issues and nasty yeast infection in his ears. We are having a heck of a time getting the upper hand on it but he is a bit better after a cortisone shot and one week into Simplicef antibiotic treatment. It's too soon to tell if it is a bacterial infection that has been allowed to spread unabated by his stupid owner, food allergies or inhalent allergies. Hopefully, we can figure it out by process of elimination. I shall look forward to visiting your new site.

Glynda

Skye

12-15-2011, 09:56 PM

I am wondering what the ultrasound is going to reveal......i would recommend double cavity u/s that way if surgery is done for anything they have more thoroughly check heart and lung. they will be checking adrenals glands as well on u/s right?

tpirovol

12-16-2011, 01:02 AM

I am going to have them check everything. Do they need to sedate her. Also do they shave her a lot?

Thanks Terry

tpirovol

12-16-2011, 01:04 AM

Let me know if I can help. I have been down that road often. I would recommend trying The Honest Kitchen maybe fish forumula. If that is still an issue then do THK preference and try Venison boiled at home.

Let me know if I can help
Terry

Hi Terry,

Congratulations on the negative LDDS. The normal range you posted is for the blood that was drawn after the dexamethasone injection. The 0 hour number you are seeing is the cortisol level before the injection and you'll be happy to know that Boo's number is within the normal reference range. We're used to seeing things in ug/dl so if I did the math right, the range is something like 28 nmol to 166 nmol so it's all good!

I recently rescued a cute little Maltese mix male who has horrible skin issues and nasty yeast infection in his ears. We are having a heck of a time getting the upper hand on it but he is a bit better after a cortisone shot and one week into Simplicef antibiotic treatment. It's too soon to tell if it is a bacterial infection that has been allowed to spread unabated by his stupid owner, food allergies or inhalent allergies. Hopefully, we can figure it out by process of elimination. I shall look forward to visiting your new site.

Glynda

addy

12-16-2011, 08:33 AM

I would recommend trying The Honest Kitchen maybe fish forumula

Hi Terry,

I have started my Zoe on this for her IBD as well. I was a bit worried would the sweet potato cause yeast but the IMS told me to go ahead and increase the amount she eats if I want to. I will say it helped firm up Zoe's poos right away:)

Will check out your allergy site for sure.

Best of luck,
addy

Squirt's Mom

12-16-2011, 10:04 AM

So glad the LDDS was normal! :)

I, too, will be checking out your allergy site for my Trinket. She has some sort of seasonal allergy(ies) that make her back oily and itchy so we will be seeing what we can learn from your site that may help! Wishing you the best of luck with it!

Hugs,
Leslie and the gang

tpirovol

12-16-2011, 08:15 PM

Hi Everyone,

I just want to confirm the below is a negative (ie. No Cushings) results. Someone said this is a positive result for cushing and kinda freaking me out. Doesn't this look like a negative diagnoises for Cushings?

http://postimage.org/image/ffvvko0nr/ --Test--
Test Results0hr = 98nmol/L
4hr = <27.7nmol/L
8hr = <27.7nmol/L

Normal: less than 40nmol/L
Hyperadrenocortisim: Greater than 40nmol/

-----------------------------------------
Below is a preliminary database I made for the site. Hope this helps some people until the site goes up. Let me know what you think.
http://www.filedropper.com/complete_1

Harley PoMMom

12-16-2011, 09:19 PM

Hi Everyone,

I just want to confirm the below is a negative (ie. No Cushings) results. Someone said this is a positive result for cushing and kinda freaking me out. Doesn't this look like a negative diagnoises for Cushings?

http://postimage.org/image/ffvvko0nr/ --Test--
Test Results0hr = 98nmol/L
4hr = <27.7nmol/L
8hr = <27.7nmol/L

Normal: less than 40nmol/L
Hyperadrenocortisim: Greater than 40nmol/

According to the IDEXX Laboratories chart, you are correct that the results do NOT show cushing's : http://www.idexx.com/pubwebresources/pdf/en_us/smallanimal/snap/cortisol/cortisol-low-dose-dexamethasone-protocol.pdf