PDA

View Full Version : Jodie's initial bloods suggest Cushings (Yorkshire Terrier almost 14 y/o)



debbielou
02-02-2011, 05:54 PM
Hi

This is my first time here and I'm in need of some support as I am a bit shell shocked at the moment.

I have suspected that my Yorkshire Terrier aged almost 14 years has had something wrong with her for some time although we put it down to the aging process. However over the last few months she has become increasingly more hyperactive and restless and yaps almost continuously - even though she is a terrier she was never a yapper in her younger days. She continuously begs for food, licks the kitchen floor, the carpets, bedding etc although she doesn't seem in any way senile. I have also noticed that her fur is very dry and lifeless and is becoming thinner and thinner and doesn't seem to be growing back as it should between grooming sessions. There are large patches of hyperpigmented skin in different parts of her body which I'm sure weren't there when she was younger. She also suffered a cruciate ligament rupture nearly two years ago which was repaired surgically very successfully. I finally went to the vets last week to request that some test be done to try and determine what is wrong with her as my gut feeling tells me something is clearly not right. Blood tests have come back with elevated Alk Phos, Alt Spgt, Gamma GT, high monocytes, bile acids high, cholesterol high, triglycerides high, sodium potassium ratio low and calcium levels low. They don't appear to have done any kidney function tests or glucose test for diabetes. Initially the vet said that she had a problem with her liver but now says that there is a possibility that she has Cushings disease. They have arranged an ACTH stimulation test to take place in two weeks time. She doesn't show any of the classic signs of liver disease as far as I can see. I am at this stage not sure what the future holds for her - she's already an old dog even though she does appear very physically fit but not sure whether old age has been masked by excess hormones and that she may be burning herself out. I just wish that they would do the ACTH test as soon as possible as I need to know for sure (although in my heart I'm sure she has cushing's). Obviously the two week interval gives me a little time to find out more about suitable and effective treatments should she be diagnosed. I would be grateful if someone could give some ideas of questions that I need to ask the vet with regard to the treatments and follow ups and anything else important.

Many thanks in anticipation of your replies

Debbielou

Harley PoMMom
02-02-2011, 06:30 PM
Hi Debbielou and Jodie,

Welcome from me and my boy Harley! I am so sorry for the circumstances that brought you here but glad you found this forum, as we are very good at hand-holding and support. ;):)

Cushing's can be a very hard disease to get diagnosed properly so it is very important that any non-adrenal illnesses, like diabetes or thyroid problems, be ruled out first.

You see, elevated liver enzymes, hyperpigmented skin and high triglycerides can be attributed to hypothyroidism as well as Cushing's.

Also, non-adrenal illnesses can create false positives on Cushing diagnostic tests.

Was an ultrasound done on Jodie?

Is Jodie drinking and urinating normally? Is she taking any other herbs or supplements?

We are here to help you in any way we can so ask all the questions you want, ok! :)

Love and hugs,
Lori

StarDeb55
02-02-2011, 06:55 PM
Debbielou, welcome to both you & Jodie! I know it's a very hard decision about treating our senior pups as I have been there. My 2nd cushpup, Harley, was diagnosed at 13. I did choose to treat him. Harley had a few small bumps in his treatment road, nothing super major, but he got 2 1/2 years longer. He passed at 15 1/2 in early October from cause unrelated to his Cushing's. Please keep us posted as to how you proceed.

Debbie

Bichonluver3
02-02-2011, 09:38 PM
A welcome from Chloe and me. We have some real experts here who can ease your fears and help you through any hurdles. They will ask you, however, to post here ALL of any tests results you have for Jodie so they can see what is happening. Try to relax - you have come to exactly the right place.
Carrol & Chloe

debbielou
02-03-2011, 07:02 AM
No Jodie hasn't had an ultrasound scan yet. As far as I can understand the blood tests have been done - they don't appear to have checked for thyroid problems, nor have they checked her kidneys nor glucose levels. The main symptoms that she has are severe restlessness, can't sit still for 2 minutes and constant yapping when she wants something - either us or more usually food. She no longer sleeps through the night wanting everybody up no matter what the time and it's impossible to settle her down again. She has a voracious appetite although I have not overfed her and she is a normal weight for her size but she constantly demands food, licks the kitchen floor etc. When out walking her she will even eat animal excrement so has to be closed watched at all times. I'm not sure about the excessive drinking but I don't think it's a problem although she does urinate in the kitchen quite frequently.

Her ACTH stimulation test is booked for 16 Feb.

Many thanks for your caring advice and support

Franklin'sMum
02-05-2011, 10:24 AM
Hi Debbielou,

Welcome to you and Jodie :) When you say she no longer sleeps through the night, does she need to pee? Peeing on the kitchen floor- was she previously house trained? Or does this happen when you're out (if the kitchen is the room you leave her in)?
My understanding (from reading here), is that licking the floor can be a sign of nausea.

Personally I would ask the vet to perform a full blood screen at the same appointment as her ACTH stim test. They usually have to send out the stim tests to an independant lab. Independant labs are usually more comprehensive than in-house testing for regular blood work as well.
It might also be an idea to take in a urine sample, so the vet can do a dipstick analysis on the spot, and they can also send that to the lab to have a UC:CR performed. The uc:cr is not a diagnostic test in and of itself, but it can rule out the possibility of cushing's.

Advice from the forum of how to obtain a urine sample from a girl, is to use something like a soup ladle or a foil pie dish taped to a ruler or something. Since Jodie is low to the ground, I wish you the best of luck :p

Hope some of that is helpful to you.

Jane, Franklin and Angel Bailey xxx