Trilostane, new tx for dogs with cushings

[sallen]

Hi,

My mom's dog probably has cushings, we are waiting for the results of all the tests. I read that Trilostane is a promising new drug, with less side effects than Lysodren. I welcome any feed back from vets and pet owners alike.

Rgds,
Sallen

[littleone1]

Hi Sallen,

Corky and I want to welcome you to a wonderful group.

As far as Trilo having less side effects, if the treatment as with Lysodren is not monitored and started at a proper dosge, both of the drugs can cause dogs to have problems. Your mom needs to make sure that she is seeing a vet or IMS that is experienced in treating Cushings.

Corky has been taking Trilostane for just about 10 months now, and has had no problems with it. His IMS started him on a lower dose and increased it as was necessary.

Others will be along that also have experience using Trilo.

We would appreciate it if you would give us some information about your mom's dog. It is helpful to know the weight and age of the dog. Also, if you can, please post the symptoms that led to the testing, the tests that were done, and when you get the results of the tests, please post them along with the reference ranges.

Terri

[Harley PoMMom]

Hi Sallen,

Welcome to you and your mom's pup from me and my boy Harley. I am sorry for the circumstances that brought you here but very glad you found this forum.

First and most important is a proper diagnosis of Cushing's. Other non-adrenal illnesses do share some of the same symptoms as Cushing's which can make this disease very hard to diagnose. Also non-adrenal illnesses can create false positives on any Cushing's tests which makes this disease misdiagnosed in many dogs. What tests are being done on your mom's pup? Could you post the results of all tests here?

IMO, either medication is safe when monitored appropriately and with owner observation and each med can have similar adverse effects. So "owner observation" is always a crucial component of treatment.

Each has it's pros and cons, they work differently, they are both safe when monitored appropriately, yet they both can have the same and serious risks and adverse effects.

One or the other may work better for an individual dog.

Another important consideration is the degree of experience one's vet has with whatever treatment he/she chooses. Cushing's requires a good partnership with one's vet.

Here are some links from our Resource Thread with info about Trilostane/Vetoryl and Lysodren/Mitotane.

Trilostane/Vetoryl Information and Resources
http://www.k9cushings.com/forum/showthread.php?t=185

Lysodren loading Instructions and related tips
http://www.k9cushings.com/forum/showthread.php?t=181

Please know you and your mom are not alone on this journey, we will help you both in any way we can.

Love and hugs,
Lori

[apollo6]

Hi Sallen,
Apollo has been on Trilostane since June 23rd and is doing well. But like everyone says before your mother starts your dog on Trilostane, make sure you have the right diagnose , there are 3 kinds: pituitary, Adrenal gland and atypical.
This is very important that you have had the tests done first: ultrasound of abdomen to see if one or both adrenal glands are enlarged, full blood panel, and then an ACHT stim test.
If it is pituitary then trilostane is a choose. It is important to know his weight also as to dosage. Don't just jump at what the specialist says.If I had listened to the specialist Apollo would have been on too high a dosage. He weighs 10lb and is on 10mg. Other will give input.
Hang in there.